San Diego Padres vs Arizona Diamondbacks Prediction, 8/4/2026 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Arizona Diamondbacks

Date: Tuesday, August 4, 2026

Location: Chase Field in Phoenix, AZ

TV: DBACKS.TV

Odds/Point Spread: San Diego (-182) Arizona (+150)

Chase Field is the site where the Arizona Diamondbacks (59-53) will attempt to defeat the San Diego Padres (58-54) on Tuesday. The moneyline on this game has San Diego at -182 and Arizona is sitting at +150. The total is 8. The pitchers who are expected to start are JP Sears and Eduardo Rodriguez.

The Padres have compiled 165 two-baggers as a team and have hit 121 baseballs out of the park. San Diego has a slugging % of .384 and have been called out on strikes 924 times, while being walked on 383 occasions. As a team, the San Diego Padres are earning 4.2 runs per outing, which ranks them 21st in the league. They have compiled 458 RBI's in addition to 866 base knocks on the season, and their team batting average is sitting at .235. They have notched a total of 472 runs scored while having a team OBP of .312.

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They have earned a strikeout to walk ratio of 2.35 and the pitching staff holds a WHIP of 1.32. Padres pitchers have relinquished 125 long balls and 484 total runs (13th in the league). San Diego has given up 919 base hits (8.4 per 9 innings) as well as 455 earned runs. The Padres have a team ERA of 4.14 so far this season (15th in MLB), and the staff has rung up 915 hitters. They have walked 389 opposing batters and their FIP comes in at 4.22 as a unit this year.

The Padres have dispatched 382 relief pitchers to the hill so far this season. The relievers have inherited 192 runners so far this season and 31.8% of those runners earned a run for their team. The relievers are sitting with 69 holds this season (9th in the league). Padres relief pitchers have stepped onto the hill with runners on base 113 times and also have had 132 appearances in high leverage situations. They have accumulated 34 saves so far this year and have blown 15 of their 49 save opportunities. The Padres relief pitchers have recorded a save rate of 69.4% and have come into the game in 121 save situations.

The San Diego Padres have a total of 2,967 putouts thus far, as well as 985 assists and 45 errors. Their fielding percentage is at .989 which is 4th in professional baseball, and have earned 92 double plays. The Padres have converted 70.0% of balls hit into play into outs out of their 8,901 innings, which ranks them 13th in baseball.

Sears has taken the hill for 590 innings and has earned 491 K's in his career. His ERA is 4.54 (298 ER's allowed) and he has a WHIP of 1.274. He has surrendered 580 base hits (8.8 hits per nine innings) and has 172 free passes. Sears (34-45 record in his career) is the owner of a FIP of 4.47 and he has gone up against 2,507 batters in the major leagues.

The Arizona Diamondbacks have accumulated an OBP of .313 and a team batting average of .241 so far this year. They have struck out on 817 occasions (28th in baseball) and have recorded 907 hits. Arizona has accounted for 107 home runs on the campaign as well as 482 runs batted in. The Diamondbacks have a SLG% of .392 and they earn 4.54 runs per game (12th in the league). They have put up 194 two-baggers, while walking 369 times and recording 508 runs.

The Diamondbacks hold a team WHIP of 1.297 with a FIP of 4.44 as a pitching staff this year. Their strikeout to walk ratio comes in at 6.90 (760 strikeouts vs 327 walks). They come in at 22nd in the league as a staff in total hits allowed with 961. They have allowed 134 long balls and they surrender 4.59 runs per 9 innings (17th in the league). The Arizona pitching staff have given up 506 runs on the season while holding a team ERA of 4.21 (465 earned runs relinquished).

Arizona relief pitchers hold an inherited score rate of 26.1% out of 142 inherited runners. Their relief pitchers have stepped onto the hill 121 times in high leverage situations and also on 97 occasions with runners on. With 111 save situations, the Diamondbacks have recorded 67 holds in addition to 14 blown saves. They rank 13th in baseball holding a save rate of 67.4%, and they have dispatched 374 bullpen pitchers to the mound this season.

In 8,937 innings on the diamond, the Diamondbacks have a defensive efficiency of 71.0% (8th in MLB). The Arizona Diamondbacks have turned 98 double plays and have notched a fielding percentage of .990 (1st in the majors). The Diamondbacks have 983 assists, 42 errors and have accumulated 2,979 putouts so far this year.

Rodriguez (104-69 career mark) has earned a 4.03 ERA while allowing 8.7 hits per 9 innings. He has a K/BB ratio of 2.77 and he has gone up against 6,112 batters in his career. He has conceded 643 earned runs while holding a WHIP of 1.320 and being the owner of a FIP of 4.0. In his pro baseball career, Rodriguez has surrendered 1,393 hits while accumulating 1,385 strikeouts in 1,434 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Arizona (+150)

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