San Diego Padres vs Boston Red Sox Prediction, 4/5/2026 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Boston Red Sox

Date: Sunday, April 5, 2026

Location: Fenway Park in Boston, MA

TV: NESN

Odds/Point Spread: San Diego (-182) Boston (+150)

Fenway Park is where the Boston Red Sox (1-5) will meet the San Diego Padres (2-4) on Sunday. The odds on this game have San Diego at -182 and Boston is priced at +150. The total is 9. The men taking the mound will be Walker Buehler and Ranger Suarez.

The Padres have tallied 10 doubles as a team and have hit 3 balls out of the stadium. San Diego has a slugging % of .301 and have struck out 51 times, while taking a walk on 21 occasions. As a squad, the San Diego Padres are notching 3.2 runs per game, which has them at 25th in the league. They have earned 16 RBI's in addition to 39 base knocks for the season, while their average at the plate is sitting at .202. They have 19 runs scored while having a team on-base percentage of .280.

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The Padres have a team ERA of 4.00 so far this year (17th in baseball), and they have struck out 60 hitters. Padres pitchers have relinquished 4 home runs and also 26 total runs (12th in the league). Their pitching staff has walked 24 opposing batters and their FIP is 3.33 as a unit over the course of the season. San Diego has conceded 46 base hits (7.7 per 9 innings) and 24 earned runs. They have a K/BB ratio of 2.50 and their pitching staff has a team WHIP of 1.30.

The relief pitchers have inherited 8 runners on the campaign with 87.5% of them ended up crossing the plate. Padres pitchers have stepped onto the hill with runners on 4 times in addition to having 4 appearances in high leverage situations. The Padres have sent 20 relief pitchers to the mound over the course of the season. The relievers have a total of 3 holds so far this year (19th in the league).

The San Diego Padres have notched a total of 162 putouts over the course of the season, as well as 46 assists and 2 errors. Their fielding rate is at .990 which is 10th in the majors, and have accumulated 4 double plays. The Padres have converted 69.0% of baseballs in play into outs in their 486 innings on the field, which has them ranked 21st in baseball.

Buehler (57-30 career record) has a FIP of 3.48 while he has gone up against 3,486 opposing hitters during his time in the major leagues. He has given up 723 base knocks (7.7 hits per nine innings) with 253 free passes. His earned run average is 3.53 (331 earned runs allowed) and he has a WHIP of 1.157. Buehler has thrown 843 innings and has racked up 849 strikeouts so far in his pro baseball career.

The Red Sox have a team slugging percentage of .347 and they score 2.83 runs per outing (28th in the league). They have 10 doubles, while taking a walk 22 times as well as scoring 17 runs. Boston is sitting with 6 home runs so far this year as well as 16 RBIs. They have been rung up on 67 instances (6th in the league) and have accounted for 42 base hits. The Boston Red Sox have compiled a team on-base percentage of .295 and a team batting average of .208 this year.

The Red Sox have a team WHIP of 1.487 with a FIP of 5.35 as a team this season. They have a ranking of 23rd in the league as a pitching staff in total hits relinquished with 53. The Boston pitching staff have surrendered 32 runs so far this season and come in with a team ERA of 4.93 (28 earned runs surrendered). They currently have a strikeout to walk ratio of 9.50 (54 strikeouts vs 23 bases on balls). They have yielded 11 long balls and they concede 5.64 runs per 9 innings (26th in baseball).

Their relief pitchers have come in 6 times in high leverage situations and on 6 occasions with runners on. They rank 19th in the league holding a save percentage of 50.0%, and they have dispatched 17 bullpen pitchers to the mound on the campaign.

Out of their 462 innings played, the Red Sox have earned a defensive efficiency of 67.2% (25th in MLB). The Boston Red Sox have turned 4 double plays and own a fielding percentage of .972 (25th in baseball). The Red Sox have racked up 51 assists, 6 errors and have 154 putouts on the season.

Suarez (53-38 win-loss record in his career) is the owner of a 3.41 earned run average and has surrendered 8.6 hits per 9 innings. His strikeout to walk ratio is 2.94 and he has gone up against 3,217 opposing batters in his career. He has allowed a total of 290 ER's while holding a WHIP of 1.274 and having a FIP of 3.4. During his pro baseball career, Suarez has surrendered 735 hits while he has accumulated 708 K's in 766 frames.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-182)

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