San Diego Padres vs Colorado Rockies Prediction, 9/16/2026 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Colorado Rockies

Date: Wednesday, September 16, 2026

Location: Coors Field in Denver, CO

TV: Rockies.TV

Odds/Point Spread: San Diego (-122) Colorado (+102)

The San Diego Padres (82-68) are headed to Coors Field on Wednesday where they will play the Colorado Rockies (55-95). The moneyline on this game has the Padres at -122 and the Rockies are coming in at +102. The total is set at 8.5. The expected starting pitchers will be Robbie Ray and Mason Adams.

As a team, the San Diego Padres are putting up 4.3 runs per game, which ranks them 21st in the league. They have accumulated 647 runs scored and have an on-base percentage of .316. The Padres have accrued 218 two-baggers as a unit and have knocked 166 baseballs out of the park. They have 623 runs batted in and 1,189 hits so far this year, and their average at the plate sits at .240. San Diego has a slugging rate of .392 and have been rung up 1,208 times, while drawing a walk on 519 occasions.

Get all of our MLB Betting Picks

Their strikeout to walk ratio is 2.40 and their pitching staff has recorded a WHIP of 1.28. Padres pitchers have given up 167 long balls and 624 runs (8th in baseball). San Diego has allowed 1,199 base hits (8.1 per 9 innings) as well as 580 earned runs. The Padres have compiled a team earned run average of 3.93 for the season (10th in MLB), and the staff has rung up 1,219 batters. They have walked 507 players from the other team and their FIP is 4.18 as a squad on the year.

The Padres relief pitchers have a save rate of 72.3% and have entered the game in 167 save situations. They have recorded 47 saves so far this season and have blown 18 out of their 65 save opportunities. The relievers have inherited 235 base runners on the campaign with 31.5% of those runners ended up scoring. Padres relief pitchers have entered the game with runners on base 144 times and also have had 179 appearances in high leverage situations. The Padres have sent 510 relievers to the hill for the year. The relievers have earned 98 holds so far this year (4th in MLB).

The Padres have turned 70.8% of baseballs in play into outs out of 11,964 innings on the diamond, which ranks them 9th in baseball. The San Diego Padres have amassed 3,988 putouts at this point in the season, as well as 1,333 assists and 63 errors. Their fielding percentage is holding steady at .988 which has them ranked 5th in the majors, and have a total of 118 double plays.

Ray (90-83 career record) sits with a FIP of 3.91 while facing 6,246 opposing hitters during his time in the majors. He has conceded 1,279 hits (7.8 hits per nine innings) and has 632 free passes. His ERA is 3.97 (651 earned runs allowed) and he has a career WHIP of 1.296. Ray has pitched in 1,474 innings and is sitting with 1,759 strikeouts so far in his career.

Colorado has a total of 166 home runs on the season as well as 673 runs batted in. They have hit 268 doubles, while walking 474 times as well as earning 703 runs. The Colorado Rockies have an on-base percentage of .323 in addition to a batting average of .253 so far this year. The Rockies have a slugging percentage of .417 and they score 4.69 runs per game (6th in the league). They have struck out on 1,309 occasions (8th in the league) and have recorded 1,293 hits.

The Rockies have a WHIP of 1.532 and have a FIP of 4.85 as a pitching staff on the campaign. They come in at 30th in baseball as a staff in total hits surrendered with 1,510. The Colorado pitching staff have conceded 873 runs on the campaign while having a team ERA of 5.59 (817 earned runs relinquished). They currently have a strikeout to walk ratio of 7.00 (1,027 strikeouts against 505 bases on balls). They have conceded 205 homers and they concede 5.97 runs per 9 innings (30th in baseball).

Sitting with 120 save situations, the Rockies have tallied 60 holds in addition to 24 blown saves. Colorado has called on relievers to enter the game in 56 save opportunities and they have come away with 32 saves. Colorado relievers hold an inherited score percentage of 31.5% out of 235 inherited runners. Their relievers have come in 144 times in high leverage situations and also on 153 occasions with runners on. They are ranked 23rd in the league holding a save rate of 57.1%, and they have sent 466 relievers to the mound for the year.

In 11,841 innings on the diamond, the Rockies are sitting with a defensive efficiency of 66.8% (30th in baseball). The Colorado Rockies have turned 120 double plays and own a fielding percentage of .982 (28th in baseball). The Rockies have accrued 1,253 assists, 94 errors and have accumulated 3,947 putouts during this campaign.

Adams (0-0 career mark) has a 3.46 ERA while allowing 8.9 hits per nine innings. His K/BB ratio is 2.44 and he has gone up against 77 opposing hitters so far in his pro baseball career. He has allowed a total of 7 earned runs while earning a WHIP of 1.484 and a FIP of 3.4. During his MLB career, Adams has allowed 18 hits while totaling 22 strikeouts in 18 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take San Diego (-122)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.