San Diego Padres vs Miami Marlins Prediction, 7/25/2026 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Miami Marlins

Date: Saturday, July 25, 2026

Location: LoanDepot Park in Miami, FL

TV: MLB.TV

Odds/Point Spread: San Diego (-128) Miami (+106)

The Miami Marlins (52-51) will take on the San Diego Padres (50-53) at LoanDepot Park on Saturday. The odds on this game have San Diego at -128 while Miami is coming in at +106. The over/under is 8.5. The pitchers taking the mound are JP Sears and Eury Perez.

The Padres have accumulated 152 two-baggers as a squad and have smacked 115 balls out of the stadium. San Diego has a slugging percentage of .383 and have struck out 860 times, while taking a walk on 350 occasions. As a squad, the San Diego Padres are knocking in 4.1 runs per game, which has them sitting at 25th in the league. They have earned 415 RBI's and 779 hits for the year, while their average at the plate comes in at .230. They have racked up 426 runs scored while holding a team on-base percentage of .307.

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The Padres hold a team earned run average of 4.25 for the year (17th in MLB), and the staff has struck out 837 batters. Padres pitchers have given up 116 home runs and 456 total runs (13th in MLB). They have walked 367 batters and their FIP is 4.27 as a squad this season. San Diego has allowed 852 hits (8.4 per 9 innings) and 429 earned runs. They have earned a K/BB ratio of 2.28 and the pitching staff holds a collective WHIP of 1.34.

Padres relief pitchers have entered the contest with runners on 103 times and also have had 116 appearances in high leverage situations. The bullpen have a total of 60 holds on the season (10th in the league). The Padres relievers have accumulated a save percentage of 69.0% and have entered the game in 104 save situations. They have compiled 29 saves this season and have blown 13 of their 42 save opportunities. The relievers have inherited 174 runners on the campaign with 32.8% of them crossing home plate. The Padres have dispatched 349 relievers to the mound for the year.

The San Diego Padres have a total of 2,724 putouts thus far, in addition to 897 assists and 40 errors. Their fielding rate is at .989 which puts them in 4th in the majors, and have accumulated 88 double plays. The Padres have turned 69.8% of baseballs in play into outs out of 8,172 innings on the diamond, which has them sitting 17th in the majors.

Sears has pitched in 582 innings and has racked up 486 punch outs so far in his pro baseball career. His ERA is 4.53 (293 earned runs allowed) and his WHIP is 1.269. He has given up 570 base knocks (8.8 hits per 9 innings) with 169 walks. Sears (33-44 win-loss record in his career) is the owner of a FIP of 4.46 and he has faced 2,468 hitters in the majors.

The Marlins hold a team SLG% of .406 and they average 4.44 runs per contest (17th in MLB). They have put up 173 doubles, while taking a walk 346 times and recording 457 runs. Miami has a total of 104 long balls so far this season and 440 runs batted in. They have been called out on strikes on 843 occasions (19th in the league) and have accounted for 861 base hits. The Miami Marlins have earned an OBP of .326 and a batting average of .251 for the year.

The Miami pitching staff have relinquished 446 runs so far this year while having an ERA of 4.05 (407 earned runs surrendered). They have surrendered 105 dingers and they surrender 4.44 runs per 9 innings (11th in the league). The Marlins are sitting with a team WHIP of 1.250 and are the owners of a FIP of 4.05 as a staff for the year. They currently have a strikeout to walk ratio of 8.60 (868 strikeouts against 351 free passes). They are sitting at 4th in the league as a staff in total hits relinquished with 779.

They sit at 15th in the league with a save rate of 63.9%, and they have sent 328 relief pitchers onto the diamond on the year. Their relievers have come in 98 times in high leverage situations in addition to 88 occasions with runners on. Sitting with 96 save situations, the Marlins have 58 holds and also 13 blown saves. Miami has called on relievers to step onto the hill in 36 save opportunities and they have walked away with 23 saves. Miami relief pitchers hold an inherited score rate of 20.3% out of 128 inherited base runners.

Out of their 8,136 innings played, the Marlins have a efficiency on defense of 70.7% (9th in the majors). The Miami Marlins have gotten 75 double plays and have earned a fielding percentage of .982 (26th in professional baseball). The Marlins have accrued 844 assists, 66 errors and have a tally of 2,712 putouts during this campaign.

Perez (17-19 career mark) is the owner of a 3.67 earned run average and has conceded 6.7 hits per 9 innings. His strikeout to walk ratio is 3.17 and he has gone up against 1,130 opposing batters so far in his MLB career. He has given up 113 earned runs while earning a WHIP of 1.099 and having a FIP of 3.6. So far in his career, Perez has surrendered 205 base knocks and he has 317 strikeouts in 277 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (-128)

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