San Diego Padres vs Milwaukee Brewers Prediction, 5/13/2026 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Milwaukee Brewers

Date: Wednesday, May 13, 2026

Location: American Family Field in Milwaukee, WI

TV: Brewers.TV

Odds/Point Spread: San Diego (+110) Milwaukee (-132)

The Milwaukee Brewers (22-16) host the San Diego Padres (24-16) at American Family Field on Wednesday. The odds on this game have the Padres at +110 while the Brewers are at -132. The over/under has been set at 8.5. The expected starting pitchers will be Michael King and Jacob Misiorowski.

The Padres have hit 62 two-baggers as a squad and have knocked 39 balls out of the stadium. San Diego has a slugging % of .370 and have been called out on strikes 333 times, while taking a walk on 131 occasions. As a squad, the San Diego Padres are earning 4.3 runs per game, which puts them at 20th in the league. They have compiled 163 RBI's and 292 base knocks this year, while their team batting average is sitting at .223. They have tallied 170 runs scored and hold an on-base percentage of .297.

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They have accumulated a K/BB ratio of 2.69 and their pitching staff holds a collective WHIP of 1.23. Padres pitchers have conceded 35 home runs and also 167 runs in total (8th in the league). San Diego has surrendered 312 base hits (7.8 per 9 innings) and also 162 earned runs. The Padres have a team earned run average of 4.07 this year (16th in baseball), and their staff has struck out 350 batters. Their pitching staff has walked 130 opposing batters and their FIP is 3.68 as a team so far this year.

The Padres have dispatched 134 relief pitchers to the hill over the course of the season. The relief pitchers have inherited 61 runners for the year and 36.1% of those runners earned a run for their team. The relief pitchers have accumulated 28 holds so far this season (7th in MLB). Padres relief pitchers have gone to the mound with runners on base 36 times and also have had 44 appearances in high leverage situations. They have accumulated 14 saves for the season and have blown 7 out of their 21 chances to get a save. The Padres relief pitchers have earned a save rate of 66.7% and have stepped onto the mound in 51 save situations.

The San Diego Padres have earned 1,074 putouts on the year, as well as 361 assists and 10 errors. Their fielding percentage is holding at .993 which has them ranked 2nd in baseball, and have accumulated 29 double plays. The Padres have converted 70.7% of balls hit into play into outs out of 3,222 innings on the field, which has them ranked 11th in professional baseball.

King has taken the ball for 539 innings and is sitting with 604 strikeouts in his pro baseball career. King (34-31 win-loss record in his career) sits with a FIP of 3.16 and he has faced 2,249 opposing batters in the majors. His earned run average is 3.20 (192 ER's allowed) and his career WHIP is 1.183. He has surrendered 446 hits (7.4 hits per 9 innings) and has had 192 free passes.

The Milwaukee Brewers have earned an on-base percentage of .333 and a batting average of .240 for the year. They have been rung up on 302 instances (28th in the league) and have a total of 305 base hits. Milwaukee has 26 HRs for the year as well as 187 runs batted in. The Brewers have a SLG% of .353 and they average 5.13 runs per game (5th in the league). They have tallied 59 two-baggers, while taking a walk 173 times as well as scoring 195 runs.

The Brewers hold a team WHIP of 1.245 and have a FIP of 3.45 as a pitching staff on the season. Their K/BB ratio sits at 9.70 (366 strikeouts against 140 walks). They rank 2nd in the league as a staff in total hits conceded with 281. They have given up 30 dingers and they relinquish 3.75 runs per 9 innings (4th in MLB). The Milwaukee pitching staff have surrendered 141 runs on the season while having a team ERA of 3.43 (129 earned runs relinquished).

With 38 save situations, the Brewers have 20 holds and also 6 blown saves. Milwaukee has had bullpen pitchers take the mound in 17 save chances and they have tallied 11 saves. Milwaukee relievers hold an inherited score percentage of 36.5% of 52 inherited runners. Their bullpen pitchers have stepped onto the mound 39 times in high leverage situations and on 34 occasions with runners on. They are currently ranked 15th in the league holding a save rate of 64.7%, and they have dispatched 126 bullpen pitchers onto the diamond on the campaign.

In 3,045 innings played, the Brewers have accumulated a defensive efficiency of 69.6% (20th in pro baseball). The Milwaukee Brewers have turned 30 double plays and have earned a fielding percentage of .987 (12th in pro baseball). The Brewers have accrued 302 assists, 17 errors and have a total of 1,015 putouts over the course of the season.

During his MLB career, Misiorowski has surrendered 76 hits while totaling 157 strikeouts in 110 innings pitched. Misiorowski (8-5 career record) has a 3.60 ERA while giving up 6.2 hits per nine innings. He has allowed 44 earned runs while earning a WHIP of 1.127 and having a FIP of 3.5. He has a K/BB ratio of 3.27 and he has gone up against 450 opposing batters in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (+110)

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