San Diego Padres vs Milwaukee Brewers Prediction, 5/14/2026 MLB Picks, Best Bets & Odds
Game: San Diego Padres vs Milwaukee Brewers
Date: Thursday, May 14, 2026
Location: American Family Field in Milwaukee, WI
TV: Brewers.TV
Odds/Point Spread: San Diego (+120) Milwaukee (-144)
American Family Field is the location where the Milwaukee Brewers (23-16) will attempt to beat the San Diego Padres (24-17) on Thursday. The moneyline on this contest has San Diego at +120 while Milwaukee is opening at -144. The over/under comes in at 9. The starting pitchers are Griffin Canning and Kyle Harrison.

San Diego has a slugging rate of .370 and have struck out 346 times, while drawing a walk on 134 occasions. They have accrued 167 runs batted in as well as 300 hits this season, while their batting average is .223. The Padres have tallied 63 doubles as a unit and have hit 40 balls out of the park. They have earned a total of 174 runs while holding a team OBP of .297. As a team, the San Diego Padres are putting up 4.2 runs per outing, which ranks them 16th in the league.
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Their strikeout to walk ratio is 2.72 and the pitching staff holds a collective WHIP of 1.24. Padres pitchers have surrendered 36 home runs in addition to 173 total runs (11th in MLB). San Diego has given up 323 hits (7.9 per 9 innings) in addition to 168 earned runs. The Padres have a team earned run average of 4.13 on the year (16th in the league), and they have rung up 359 batters. Their pitching staff has walked 132 players from the other team and their FIP comes in at 3.67 as a team over the course of the season.
The Padres relief pitchers have compiled a save rate of 66.7% and stepped onto the hill in 51 save situations. They have 14 saves for the year and have not converted 7 out of their 21 save chances. The relief pitchers have inherited 63 runners over the course of the season with 34.9% of them ended up scoring. Padres bullpen pitchers have gone to the mound with players on base 37 times in addition to having 44 appearances in high leverage situations. The Padres have sent 137 relievers to the hill this season. The relievers have recorded 28 holds on the year (7th in the league).
The Padres have converted 70.4% of baseballs in play into outs out of 3,294 innings on the diamond, which ranks them 14th in the majors. The San Diego Padres have a tally of 1,098 putouts over the course of the season, in addition to 368 assists and 10 errors. Their fielding percentage is holding steady at .993 which is 1st in pro baseball, and have accumulated 30 double plays.
Canning has taken the ball for 593 frames and has earned 565 K's so far in his MLB career. Canning (32-38 career mark) is the owner of a FIP of 4.62 while facing 2,543 batters in the majors. His earned run average is 4.69 (309 ER's allowed) and he has a WHIP of 1.344. He has allowed 574 hits (8.7 hits per nine innings) and has 223 free passes.
The Milwaukee Brewers have an OBP of .334 in addition to a batting average of .243 on the season. They have been rung up on 311 instances (28th in the league) and are sitting with 317 base hits. Milwaukee has compiled 27 HRs on the campaign to go along with 193 runs batted in. The Brewers have a SLG% of .358 and they are recording 5.15 runs per game (5th in MLB). They have 62 two-baggers, while taking a walk 175 times and scoring 201 runs.
The Milwaukee pitching staff have conceded 145 runs so far this year and come in with a team ERA of 3.45 (133 earned runs surrendered). They have allowed 31 homers and they give up 3.76 runs per 9 innings (4th in baseball). The Brewers hold a team WHIP of 1.245 and have a FIP of 3.43 as a staff for the season. Their K/BB ratio comes in at 9.80 (379 strikeouts against 143 free passes). They have a ranking of 2nd in MLB as a pitching staff in total hits surrendered with 289.
They are ranked 11th in MLB with a save rate of 66.7%, and they have dispatched 130 relief pitchers onto the field for the season. Their relievers have come in 40 times in high leverage situations and also on 35 occasions with runners on base. With 42 save situations, the Brewers have recorded 23 holds in addition to 6 blown saves. Milwaukee has called on relievers to enter the contest in 18 save chances and they have earned 12 saves. Milwaukee relievers have an inherited score percentage of 35.8% out of 53 inherited base runners.
The Milwaukee Brewers have turned 31 double plays and own a fielding percentage of .988 (13th in baseball). The Brewers have recorded 309 assists, 17 errors and have accounted for 1,042 putouts over the course of the season. In 3,126 innings on the diamond, the Brewers have earned a defensive efficiency of 69.5% (21st in pro baseball).
So far in his pro baseball career, Harrison has surrendered 217 base knocks and he has 232 K's in 227 frames. Harrison (12-10 record in his career) holds a 4.12 ERA while allowing 8.6 hits per nine innings. He has allowed a total of 104 earned runs while holding a WHIP of 1.306 and having a FIP of 4.1. He has a K/BB ratio of 2.90 and he has faced 975 opposing hitters so far in his pro baseball career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take San Diego (+120)
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