San Francisco Giants vs Los Angeles Dodgers Prediction, 9/20/2026 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Los Angeles Dodgers

Date: Sunday, September 20, 2026

Location: Dodger Stadium in Los Angeles, CA

TV: Spectrum SportsNet LA

Odds/Point Spread: San Francisco (+110) Los Angeles (-130)

The Los Angeles Dodgers (93-60) will try to defeat the San Francisco Giants (64-89) at Dodger Stadium on Sunday. The line on this matchup has the Giants at +110 while the Dodgers are at -130. The over/under is set at 8.5. The expected starting pitchers will be Landen Roupp and Justin Wrobleski.

As a team, the San Francisco Giants are earning 4.2 runs per contest, which has them at 23rd in baseball. They have accounted for 649 runs scored and hold an OBP of .310. The Giants have tallied 252 two-baggers as a squad and have knocked 175 baseballs out of the park. They have accounted for 626 RBI's and 1,288 base knocks for the year, while their average at the plate comes in at .248. San Francisco has a slugging percentage of .408 and have been rung up 1,233 times, while drawing a walk on 429 occasions.

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Their strikeout to walk ratio is 2.00 and their pitching staff holds a collective WHIP of 1.36. Giants pitchers have yielded 144 long balls and 719 runs in total (23rd in baseball). San Francisco has given up 1,265 hits (8.4 per 9 innings) as well as 652 earned runs. The Giants have an ERA of 4.34 on the campaign (23rd in MLB), and their staff has rung up 1,142 batters. They have walked 571 opposing hitters and their FIP sits at 4.20 as a team over the course of the season.

The Giants relievers have recorded a save percentage of 53.7% and have come into the game in 137 save situations. They have tallied 29 saves for the year and have blown 25 of 54 save chances. The bullpen pitchers have inherited 271 runners this year with 34.7% of those players crossing the plate. Giants bullpen pitchers have entered the contest with runners on base 174 times as well as having 133 appearances in high leverage situations. The Giants have sent 488 relief pitchers to the mound so far this season. The relievers have earned 83 holds over the course of the season (16th in baseball).

The Giants have transformed 69.6% of balls hit into play into outs in their 12,159 innings, which has them sitting 18th in the majors. The San Francisco Giants have earned 4,053 putouts thus far, in addition to 1,435 assists and 102 errors. Their fielding percentage is holding at .982 which ranks 30th in the majors, and have accumulated 137 double plays.

Roupp has taken the mound for 312 innings and has racked up 292 punch outs in his MLB career. Roupp (17-23 win-loss record in his career) is the owner of a FIP of 3.81 and he has faced 1,350 hitters during his time in the major leagues. His ERA is 3.87 (134 earned runs allowed) and he has a WHIP of 1.372. He has given up 282 base hits (8.1 hits per 9 innings) and has had 146 free passes.

Los Angeles is sitting with 190 home runs for the year to go along with 715 RBIs. They have tallied 249 doubles, while taking a walk 597 times and putting up 759 runs. The Los Angeles Dodgers are sitting with a team OBP of .338 as well as a team batting average of .255 on the season. The Dodgers hold a slugging percentage of .421 and they are earning 4.96 runs per game (4th in the league). They have been rung up on 1,198 instances (27th in MLB) and have accounted for 1,312 base knocks.

The Dodgers hold a team WHIP of 1.162 and are the owners of a FIP of 3.80 as a team so far this season. Their K/BB ratio sits at 9.40 (1,411 strikeouts against 463 bases on balls). They are currently ranked 1st in baseball as a pitching staff in total hits conceded with 1,109. They have conceded 169 long balls and they yield 3.86 runs per 9 innings (2nd in baseball). The Los Angeles pitching staff have given up 580 runs this season and come in with a team ERA of 3.64 (548 earned runs surrendered).

Sitting with 161 save situations, the Dodgers have earned 95 holds and also 22 blown saves. Los Angeles has had relievers step onto the hill in 65 save opportunities and they have converted 43 saves. Los Angeles bullpen pitchers have an inherited score percentage of 35.0% out of 177 inherited runners. Their relief pitchers have come in 162 times in high leverage situations in addition to 110 occasions with runners on. They sit at 13th in the league with a save percentage of 66.2%, and they have sent 501 bullpen pitchers to the hill over the course of the season.

In their 12,183 innings on the diamond, the Dodgers have accumulated a defensive efficiency of 72.0% (2nd in the majors). The Los Angeles Dodgers have gotten 87 double plays and hold a fielding percentage of .989 (3rd in MLB). The Dodgers have accrued 1,230 assists, 59 errors and have accumulated 4,061 putouts this season.

Wrobleski (17-12 win-loss mark in his career) has earned a 4.18 earned run average and has conceded 8.4 hits per nine innings. He has a strikeout to walk ratio of 3.38 and he has gone up against 995 opposing batters in his pro baseball career. He has surrendered 111 ER's while earning a WHIP of 1.196 and a FIP of 4.1. In his pro baseball career, Wrobleski has allowed 222 base hits and he has 216 strikeouts in 239 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Los Angeles (-130)

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