Seattle Mariners vs Houston Astros Prediction, 5/12/2026 MLB Picks, Best Bets & Odds
Game: Seattle Mariners vs Houston Astros
Date: Tuesday, May 12, 2026
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Seattle (-132) Houston (+110)
The Seattle Mariners (19-22) are headed to Daikin Park on Tuesday where they will try to beat the Houston Astros (16-25). The line on this matchup has Seattle at -132 and Houston opens at +110. The betting total comes in at 8. The pitchers taking the mound are Bryan Woo and Tatsuya Imai.

The Mariners have accrued 54 doubles as a unit and have smacked 46 balls out of the park. Seattle owns a slugging percentage of .378 and have been called out on strikes 379 times, while taking a walk on 158 occasions. As a squad, the Seattle Mariners are recording 4.1 runs per game, which ranks them 25th in baseball. They have compiled 162 RBI's and 309 base knocks for the season, and their batting average sits at .229. They have earned 167 runs and have an OBP of .319.
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Their strikeout to walk ratio sits at 3.48 and the pitching staff has earned a collective WHIP of 1.23. Mariners pitchers have surrendered 43 home runs and 165 runs in total (7th in MLB). Seattle has yielded 348 hits (8.6 per 9 innings) as well as 153 earned runs. The Mariners have a team earned run average of 3.78 on the season (8th in the league), and the staff has rung up 345 hitters. Their pitching staff has walked 99 opposing hitters and their FIP is 3.78 as a team over the course of the season.
The Mariners bullpen have accumulated a save rate of 64.7% and stepped onto the hill in 38 save situations. They have recorded 11 saves for the season and have missed out on 6 out of their 17 save opportunities. The bullpen pitchers have inherited 41 base runners so far this season with 12.2% of them crossing home plate. Mariners bullpen pitchers have come into the game with opponents on base 31 times and also have had 51 appearances in high leverage situations. The Mariners have sent 127 relievers to the mound for the year. The bullpen have tallied 21 holds for the year (20th in the league).
The Mariners have converted 68.8% of balls hit into play into outs out of 3,279 innings on the field, which has them sitting 25th in pro baseball. The Seattle Mariners have amassed 1,093 putouts over the course of the season, in addition to 346 assists and 15 errors. Their fielding percentage is holding steady at .990 which has them sitting 6th in professional baseball, and have 41 double plays.
Woo has pitched in 442 frames and has tallied 430 K's in his pro baseball career. Woo (30-17 career win-loss record) holds a FIP of 3.25 and he has faced 1,761 batters during his time in the major leagues. His ERA is 3.30 (162 earned runs allowed) and his career WHIP is 0.984. He has given up 347 base hits (7.1 hits per nine innings) and has had 88 walks.
The Houston Astros have tallied a team on-base percentage of .333 and a batting average of .258 this year. They have struck out on 320 occasions (22nd in baseball) and have accounted for 359 hits. Houston has accumulated 52 home runs so far this season as well as 186 runs batted in. The Astros hold a team SLG% of .429 and they are recording 4.78 runs per outing (8th in baseball). They have hit 77 two-baggers, while getting a free base 145 times as well as putting up 196 runs.
The Astros hold a team WHIP of 1.596 and have a FIP of 5.02 as a staff this year. They rank 26th in the league as a staff in total hits given up with 360. The Houston pitching staff have surrendered 230 runs this season while holding an ERA of 5.57 (221 earned runs allowed). Their K/BB ratio comes in at 9.10 (363 strikeouts vs 210 free passes). They have given up 54 long balls and they surrender 5.80 runs per 9 innings (30th in MLB).
With 22 save situations, the Astros have earned 13 holds in addition to 1 blown save. Houston has had relief pitchers enter the game in 9 save opportunities and they have earned 8 saves. Houston relievers hold an inherited score percentage of 27.6% of 76 inherited runners. Their relievers have stepped onto the hill 29 times in high leverage situations and on 45 occasions with runners on base. They rank 1st in baseball with a save rate of 88.9%, and they have dispatched 130 relievers to the hill so far this season.
The Houston Astros have turned 39 double plays and have a fielding percentage of .989 (7th in professional baseball). The Astros have racked up 307 assists, 15 errors and are sitting with 1,072 putouts over the course of the season. Out of their 3,216 innings played, the Astros have a defensive efficiency of 67.5% (28th in the majors).
During his pro baseball career, Imai has given up 7 base hits while he has earned 13 strikeouts in 8 innings pitched. He has conceded 7 ER's while earning a WHIP of 2.195 and being the owner of a FIP of 7.6. He has a K/BB ratio of 1.18 and he has gone up against 44 opposing batters during his career. Imai (1-0 career win-loss record) is the owner of a 7.68 ERA and has surrendered 7.7 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Seattle (-132)
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Additional Resources:
Houston Astros - Twitter
Seattle Mariners - Twitter
