Seattle Mariners vs Houston Astros Prediction, 5/13/2026 MLB Picks, Best Bets & Odds

Game: Seattle Mariners vs Houston Astros

Date: Wednesday, May 13, 2026

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Seattle (-128) Houston (+106)

The Houston Astros (16-26) host the Seattle Mariners (20-22) at Daikin Park on Wednesday. The moneyline on this contest has Seattle at -128 while Houston is coming in at +106. The over/under is 8.5. The pitchers who are expected to start will be Bryce Miller and Lance McCullers Jr..

Seattle has a slugging % of .376 and have struck out 386 times, while taking a walk on 159 occasions. They have tallied 165 RBI's and 316 base knocks so far this season, and their average at the plate is sitting at .229. The Mariners have compiled 54 two-baggers as a squad and have knocked 47 balls out of the park. They have accumulated 170 runs while having a team on-base percentage of .317. As a squad, the Seattle Mariners are putting up 4.1 runs per outing, which has them sitting at 25th in the league.

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They have earned a strikeout to walk ratio of 3.51 and the pitching staff has recorded a WHIP of 1.23. Mariners pitchers have surrendered 43 home runs and 166 runs in total (7th in MLB). Seattle has surrendered 357 hits (8.6 per 9 innings) and 154 earned runs. The Mariners are sitting with a team ERA of 3.71 so far this year (7th in baseball), and the staff has rung up 358 hitters. Their pitching staff has walked 102 hitters and their FIP is 3.73 as a squad this year.

The Mariners relievers have a save rate of 66.7% and have come into the game in 42 save situations. They have accumulated 12 saves on the campaign and have blown 6 of their 18 chances to get a save. The bullpen pitchers have inherited 41 base runners on the year and 12.2% of those players earned a run for their team. Mariners pitchers have gone to the mound with runners on base 31 times in addition to having 54 appearances in high leverage situations. The Mariners have sent 131 relievers to the mound over the course of the season. The relief pitchers are sitting with 24 holds so far this season (13th in baseball).

The Mariners have converted 68.6% of baseballs in play into outs out of 3,360 innings on the diamond, which has them ranked 25th in baseball. The Seattle Mariners have accumulated 1,120 putouts at this point in the season, in addition to 356 assists and 15 errors. Their fielding percentage is holding at .990 which is 5th in baseball, and have accumulated 42 double plays.

Miller has taken the ball for 402 frames and has tallied 364 punch outs in his pro baseball career. Miller (24-21 career win-loss mark) is the owner of a FIP of 3.95 and he has gone up against 1,633 opposing hitters during his time in the majors. His ERA is 4.01 (179 earned runs allowed) and he has a WHIP of 1.127. He has given up 348 base hits (7.8 hits per 9 innings) with 105 free passes.

Houston has compiled 52 HRs this year to go along with 187 runs batted in. They have put up 77 two-baggers, while taking a walk 148 times as well as putting up 197 runs. The Houston Astros have compiled an on-base percentage of .333 as well as a batting average of .258 for the year. The Astros hold a team slugging percentage of .425 and they are earning 4.69 runs per contest (9th in MLB). They have been called out on strikes on 333 occasions (18th in MLB) and have totaled 368 base hits.

The Houston pitching staff have given up 233 runs this season while holding an ERA of 5.51 (224 earned runs yielded). They have surrendered 55 HR's and they concede 5.73 runs per 9 innings (30th in the league). The Astros are sitting with a team WHIP of 1.579 in addition to having a FIP of 4.98 as a unit on the season. Their K/BB ratio is 9.10 (370 strikeouts against 211 bases on balls). They are currently ranked 27th in the league as a staff in total hits allowed with 367.

Houston relievers hold an inherited score rate of 27.6% out of 76 inherited base runners. Their relief pitchers have stepped onto the hill 29 times in high leverage situations and also on 45 occasions with runners on base. With 22 save situations, the Astros have tallied 13 holds in addition to 1 blown save. They are ranked 1st in baseball with a save rate of 88.9%, and they have sent 132 relievers onto the field this year.

In 3,297 innings on the diamond, the Astros have accumulated a efficiency on defense of 67.7% (28th in professional baseball). The Houston Astros have gotten 40 double plays and hold a fielding percentage of .990 (7th in the majors). The Astros have racked up 316 assists, 15 errors and have accounted for 1,099 putouts this season.

In his career, McCullers has allowed 695 hits while tallying 898 strikeouts in 808 frames. He has given up a total of 346 ER's while earning a WHIP of 1.300 and a FIP of 3.8. He has a strikeout to walk ratio of 2.53 and he has faced 3,439 opposing batters during his MLB career. McCullers (53-40 career record) is the owner of a 3.85 earned run average while allowing 7.7 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Seattle (-128)

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