Seattle Mariners vs Houston Astros Prediction, 5/14/2026 MLB Picks, Best Bets & Odds

Game: Seattle Mariners vs Houston Astros

Date: Thursday, May 14, 2026

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Seattle (-145) Houston (+125)

Daikin Park is where the Houston Astros (16-27) will try to defeat the Seattle Mariners (21-22) on Thursday. The line on this matchup has the Mariners at -145 while the Astros are priced at +125. The over/under is 9. The pitchers who are expected to start will be Luis Castillo and Mike Burrows.

As a team, the Seattle Mariners are putting up 4.2 runs per contest, which ranks them 21st in MLB. They have accounted for 180 runs scored and hold an OBP of .320. The Mariners have accounted for 56 two-baggers as a squad and have hit 49 balls out of the park. They have 175 RBI's in addition to 327 hits on the season, and their team batting average is .231. Seattle owns a slugging percentage of .380 and have struck out 390 times, while drawing a walk on 165 occasions.

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They have earned a strikeout to walk ratio of 3.52 and their pitching staff has a collective WHIP of 1.22. Mariners pitchers have surrendered 43 home runs and 168 runs (7th in MLB). Seattle has given up 362 base hits (8.5 per 9 innings) in addition to 156 earned runs. The Mariners have an earned run average of 3.67 over the course of the season (8th in the league), and they have struck out 370 batters. They have walked 105 opposing players and their FIP comes in at 3.67 as a team on the season.

Mariners relief pitchers have gone to the mound with opponents on base 31 times in addition to having 54 appearances in high leverage situations. The relievers have a total of 24 holds for the year (15th in MLB). The Mariners relief pitchers have earned a save percentage of 66.7% and have come into the game in 42 save situations. They have 12 saves on the campaign and have blown 6 of 18 chances to get a save. The bullpen pitchers have inherited 41 base runners this year and 12.2% of those runners earned a run for their team. The Mariners have dispatched 133 relievers to the mound this season.

The Mariners have turned 68.7% of balls hit into play into outs out of 3,441 innings, which has them sitting 24th in baseball. The Seattle Mariners have accounted for 1,147 putouts on the year, in addition to 359 assists and 15 errors. Their fielding rate is holding steady at .990 which is 5th in MLB, and have accumulated 42 double plays.

Castillo has taken the hill for 1,448 frames and is sitting with 1,530 punch outs during his pro baseball career. His ERA is 3.64 (585 earned runs allowed) and he has a WHIP of 1.190. He has allowed 1,257 hits (7.8 hits per nine innings) with 466 free passes. Castillo (84-88 career win-loss record) is the owner of a FIP of 3.58 while he has gone up against 6,002 batters during his time in the majors.

The Houston Astros hold an on-base percentage of .330 and a batting average of .255 on the campaign. They have been rung up on 345 occasions (17th in the league) and have tallied 373 hits. Houston is sitting with 52 home runs this season to go along with 189 RBIs. The Astros have a team SLG% of .421 and they average 4.63 runs per contest (10th in MLB). They have hit 79 two-baggers, while taking a walk 151 times and putting up 199 runs.

The Houston pitching staff have relinquished 243 runs for the year and come in with a team ERA of 5.61 (234 earned runs relinquished). They have conceded 57 homers and they allow 5.83 runs per 9 innings (30th in the league). The Astros have a team WHIP of 1.586 in addition to having a FIP of 5.05 as a unit over the course of the season. Their K/BB ratio comes in at 9.00 (374 strikeouts vs 217 walks). They rank 27th in MLB as a staff in total hits allowed with 378.

They sit at 1st in baseball holding a save percentage of 88.9%, and they have dispatched 134 bullpen pitchers to the mound this season. Their relievers have come in 29 times in high leverage situations and on 45 occasions with runners on. With 22 save situations, the Astros have earned 13 holds in addition to 1 blown save. Houston has had relief pitchers step onto the hill in 9 save chances and they have walked away with 8 saves. Houston relief pitchers hold an inherited score rate of 27.6% of 76 inherited runners.

The Houston Astros have gotten 41 double plays and have notched a fielding percentage of .990 (7th in pro baseball). The Astros have 326 assists, 15 errors and have amassed 1,126 putouts so far this year. In 3,378 innings played, the Astros have a defensive efficiency of 67.8% (27th in pro baseball).

So far in his pro baseball career, Burrows has allowed 142 hits while earning 141 punch outs in 143 frames. Burrows (5-8 career win-loss mark) is the owner of a 4.27 ERA and has conceded 8.9 hits per 9 innings. He has surrendered a total of 68 ER's while earning a WHIP of 1.326 and having a FIP of 4.2. He has a strikeout to walk ratio of 2.94 and he has faced 610 opposing hitters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Houston (+125)

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