St. Louis Cardinals vs Cincinnati Reds Prediction, 8/19/2026 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Cincinnati Reds

Date: Wednesday, August 19, 2026

Location: Great American Ball Park in Cincinnati, OH

TV: Reds.TV

Odds/Point Spread: St. Louis (-122) Cincinnati (+102)

The Cincinnati Reds (59-64) will go up against the St. Louis Cardinals (63-61) at Great American Ball Park on Wednesday. The moneyline on this matchup has the Cardinals at -122 while the Reds are opening at +102. The total is set at 8.5. The expected starting pitchers will be Matthew Liberatore and Chase Burns.

St. Louis has a slugging percentage of .382 and have struck out 952 times, while being walked on 403 occasions. They have amassed 535 RBI's and 997 base knocks so far this year, while their team batting average comes in at .240. The Cardinals have hit 176 doubles as a unit and have smacked 129 baseballs out of the park. They have tallied 548 runs scored while holding a team on-base percentage of .316. As a team, the St. Louis Cardinals are scoring 4.4 runs/g, which has them at 18th in baseball.

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They have accrued a K/BB ratio of 2.24 and the pitching staff has earned a collective WHIP of 1.34. Cardinals pitchers have surrendered 122 long balls and 541 runs (12th in the league). St. Louis has given up 1,056 hits (8.6 per 9 innings) and 497 earned runs. The Cardinals hold a team ERA of 4.04 over the course of the season (12th in MLB), and the staff has struck out 946 hitters. They have walked 422 players from the other team and their FIP is 4.11 as a unit on the season.

The Cardinals have sent 413 relievers to the hill this year. The bullpen pitchers have inherited 192 base runners on the year with 36.5% of them crossing the plate. The relief pitchers have racked up 79 holds so far this season (7th in baseball). Cardinals pitchers have entered the game with players on base 130 times and also have had 153 appearances in high leverage situations. They have compiled 35 saves on the year and have missed out on 22 out of their 57 save opportunities. The Cardinals relief pitchers have a save percentage of 61.4% and have entered the game in 140 save situations.

The Cardinals have turned 69.5% of balls in play into outs in their 9,957 innings, which ranks them 20th in professional baseball. The St. Louis Cardinals have accounted for 3,319 putouts at this point in the season, as well as 1,174 assists and 54 errors. Their fielding percentage is holding at .988 which ranks 5th in MLB, and have earned 124 double plays.

Liberatore (21-34 career win-loss mark) sits with a FIP of 4.68 while he has gone up against 1,961 hitters in the major leagues. He has given up 479 hits (9.5 hits per 9 innings) and has 155 free passes. His earned run average is 4.75 (239 ER's allowed) and his WHIP is 1.400. Liberatore has taken the ball for 453 frames and has tallied 388 punch outs so far in his career.

The Reds have a SLG% of .393 and they score 4.08 runs per contest (25th in the league). They have recorded 177 doubles, while getting a free base 443 times as well as putting up 502 runs. Cincinnati has 161 long balls over the course of the season and 479 RBIs. They have struck out on 1,166 instances (3rd in the league) and have totaled 925 base hits. The Cincinnati Reds have accumulated a team on-base percentage of .306 as well as a team batting average of .226 on the year.

The Cincinnati pitching staff have conceded 588 runs so far this season while holding a team ERA of 4.51 (548 earned runs conceded). They have allowed 155 homers and they give up 4.84 runs per 9 innings (23rd in MLB). The Reds are sitting with a team WHIP of 1.404 in addition to having a FIP of 4.67 as a squad this season. They have earned a K/BB ratio of 8.20 (992 strikeouts against 509 free passes). They are sitting at 18th in baseball as a staff in total hits conceded with 1,026.

Sitting with 123 save situations, the Reds have earned 69 holds in addition to 19 blown saves. Cincinnati has had relief pitchers step onto the mound in 51 save opportunities and they have come away with 32 saves. Cincinnati relievers have an inherited score percentage of 28.0% of 193 inherited base runners. Their bullpen pitchers have come in 156 times in high leverage situations and on 134 occasions with base runners. They are currently ranked 16th in the league with a save percentage of 62.7%, and they have sent 436 bullpen pitchers to the mound on the season.

The Cincinnati Reds have gotten 85 double plays and have notched a fielding percentage of .985 (19th in MLB). The Reds have 994 assists, 67 errors and are sitting with 3,279 putouts this year. In 9,837 innings on the field, the Reds have a defensive efficiency of 70.3% (12th in pro baseball).

So far in his career, Burns has conceded 138 hits and he has 218 K's in 174 innings. Burns (14-5 career record) holds a 3.00 earned run average and has surrendered 7.1 hits per 9 innings. He has surrendered 58 earned runs while holding a WHIP of 1.149 and a FIP of 3.0. His strikeout to walk ratio is 3.52 and he has gone up against 714 opposing batters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take St. Louis (-122)

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