St. Louis Cardinals vs Cincinnati Reds Prediction, 8/20/2026 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Cincinnati Reds

Date: Thursday, August 20, 2026

Location: Great American Ball Park in Cincinnati, OH

TV: Reds.TV

Odds/Point Spread: St. Louis (-160) Cincinnati (+132)

The Cincinnati Reds (60-66) are welcoming the St. Louis Cardinals (65-62) at Great American Ball Park on Thursday. The moneyline on this game has the Cardinals at -160 while the Reds are at +132. The total has been set at 8.5. The starting pitchers are Michael McGreevy and Brady Singer.

St. Louis has a slugging percentage of .382 and have struck out 981 times, while taking a walk on 413 occasions. They have accumulated 545 RBI's and 1,023 hits this season, and their team batting average is at .240. The Cardinals have hit 183 two-baggers as a team and have knocked 131 balls out of the park. They have a total of 558 runs scored while holding a team OBP of .316. As a squad, the St. Louis Cardinals are notching 4.4 runs per game, which is 19th in baseball.

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The Cardinals hold a team ERA of 3.99 on the campaign (12th in MLB), and their staff has struck out 979 batters. Cardinals pitchers have allowed 124 home runs and also 548 runs (12th in the league). Their pitching staff has walked 427 opposing players and their FIP is 4.06 as a squad for the season. St. Louis has surrendered 1,075 base hits (8.5 per 9 innings) and 503 earned runs. Their strikeout to walk ratio is 2.29 and their pitching staff has a collective WHIP of 1.33.

The Cardinals bullpen have recorded a save percentage of 62.7% and have stepped onto the mound in 148 save situations. They have 37 saves over the course of the season and have not converted 22 of 59 save chances. The bullpen pitchers have inherited 192 runners for the season and 36.5% of those runners crossing the plate. Cardinals relief pitchers have entered the game with runners on 131 times in addition to having 161 appearances in high leverage situations. The Cardinals have dispatched 424 relievers to the mound on the campaign. The bullpen have notched 85 holds on the campaign (4th in baseball).

The St. Louis Cardinals have accumulated 3,400 putouts this year, in addition to 1,196 assists and 54 errors. Their fielding percentage is holding steady at .988 which ranks 3rd in MLB, and they have turned 126 double plays. The Cardinals have turned 69.6% of balls hit into play into outs out of 10,200 innings, which has them sitting 18th in pro baseball.

McGreevy has thrown 250 innings and has earned 167 strikeouts so far in his MLB career. His earned run average is 3.71 (103 earned runs allowed) and his WHIP is 1.195. He has surrendered 243 hits (8.7 hits per nine innings) and has had 56 walks. McGreevy (16-13 career record) has a FIP of 3.65 and he has faced 1,024 hitters in the major leagues.

Cincinnati has hit 163 home runs so far this year and 486 RBIs. They have 181 doubles, while walking 448 times and putting up 509 runs. The Cincinnati Reds hold an on-base percentage of .305 as well as a team batting average of .226 on the season. The Reds have a SLG% of .391 and they are recording 4.04 runs per contest (27th in the league). They have struck out on 1,199 instances (2nd in MLB) and have recorded 944 base hits.

The Reds have a WHIP of 1.401 and are the owners of a FIP of 4.63 as a unit so far this season. They rank 20th in the league as a pitching staff in total hits relinquished with 1,051. The Cincinnati pitching staff have allowed 598 runs so far this year and come in with a team ERA of 4.48 (558 earned runs yielded). They currently have a K/BB ratio of 8.20 (1,021 strikeouts against 519 bases on balls). They have surrendered 157 homers and they allow 4.80 runs per 9 innings (21st in MLB).

Cincinnati relief pitchers have an inherited score percentage of 27.8% of 194 inherited runners. Their bullpen pitchers have come in 157 times in high leverage situations and on 136 occasions with runners on. With 123 save situations, the Reds have tallied 69 holds and 19 blown saves. They sit at 17th in baseball with a save rate of 62.7%, and they have dispatched 443 bullpen pitchers onto the diamond so far this season.

The Cincinnati Reds have turned 87 double plays and hold a fielding percentage of .984 (20th in professional baseball). The Reds have accrued 1,017 assists, 69 errors and have a tally of 3,363 putouts during this campaign. In 10,089 innings on the field, the Reds have a defensive efficiency of 70.3% (13th in the majors).

Singer (55-67 win-loss record in his career) holds a 4.29 ERA and has surrendered 9.0 hits per nine innings. He has a strikeout to walk ratio of 2.89 and he has faced 4,207 hitters thus far in his career. He has allowed a total of 467 earned runs while holding a WHIP of 1.326 and being the owner of a FIP of 4.2. So far in his pro baseball career, Singer has given up 984 base hits and he has 912 punch outs in 980 frames.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take St. Louis (-160)

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