St. Louis Cardinals vs Detroit Tigers Prediction, 4/3/2026 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Detroit Tigers

Date: Friday, April 3, 2026

Location: Comerica Park in Detroit, MI

TV: Detroit SportsNet

Odds/Point Spread: St. Louis (-160) Detroit (+132)

Comerica Park is the site where the Detroit Tigers (2-4) will try to defeat the St. Louis Cardinals (4-2) on Friday. The moneyline on this game has St. Louis at -160 and Detroit opens at +132. The total is 9. The pitchers taking the mound will be Michael McGreevy and Framber Valdez.

As a unit, the St. Louis Cardinals are putting up 4.8 runs per game, which has them at 9th in baseball. They are sitting with 29 runs and have an on-base percentage of .287. The Cardinals have accounted for 9 two-baggers as a team and have knocked 7 baseballs out of the park. They have accrued 28 runs batted in and 47 base knocks for the year, while their average at the plate is .232. St. Louis owns a slugging percentage of .379 and have been called out on strikes 49 times, while drawing a walk on 17 occasions.

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The Cardinals have a team ERA of 4.26 over the course of the season (20th in MLB), and their staff has rung up 34 batters. Cardinals pitchers have allowed 2 home runs in addition to 28 total runs (21st in the league). They have walked 26 batters and their FIP is 3.85 as a team on the year. St. Louis has allowed 59 base hits (9.3 per 9 innings) and 27 earned runs. Their strikeout to walk ratio is 1.31 and the pitching staff holds a collective WHIP of 1.49.

Cardinals relief pitchers have entered the game with runners on 10 times as well as having 10 appearances in high leverage situations. The relievers have notched 6 holds on the year (6th in the league). The relievers have inherited 18 base runners on the year with 44.4% of them ended up scoring. The Cardinals have dispatched 26 relief pitchers to the mound over the course of the season.

The St. Louis Cardinals have earned 171 putouts on the year, as well as 63 assists and 4 errors. Their fielding percentage is currently at .983 which puts them in 20th in baseball, and have 4 double plays. The Cardinals have converted 68.9% of baseballs in play into outs in their 513 innings, which ranks them 22nd in pro baseball.

McGreevy has pitched in 124 innings and is sitting with 81 strikeouts in his career. His earned run average is 3.77 (52 earned runs allowed) and his WHIP is 1.127. He has conceded 116 base hits (8.4 hits per 9 innings) with 24 walks. McGreevy (11-4 career mark) holds a FIP of 3.71 while he has faced 507 hitters in the majors.

Detroit is sitting with 1 home run so far this year to go along with 24 runs batted in. They have notched 12 two-baggers, while getting a free base 22 times as well as putting up 24 runs. The Detroit Tigers are sitting with a team OBP of .296 as well as a team batting average of .215 on the campaign. The Tigers have a team slugging % of .300 and they earn 4.00 runs per contest (18th in MLB). They have been called out on strikes on 60 occasions (10th in the league) and are sitting with 43 base hits.

The Tigers are sitting with a team WHIP of 1.320 with a FIP of 4.27 as a squad for the year. They are sitting at 12th in the league as a staff in total hits allowed with 45. The Detroit pitching staff have allowed 24 runs on the campaign while having a team ERA of 3.78 (21 earned runs relinquished). They have earned a strikeout to walk ratio of 7.70 (43 strikeouts vs 21 walks). They have conceded 6 HR's and they concede 4.32 runs per 9 innings (13th in the league).

They are currently ranked 21st in MLB holding a save percentage of 50.0%, and they have dispatched 17 relievers onto the field on the year. Their bullpen pitchers have stepped onto the mound 3 times in high leverage situations and also on 9 occasions with runners on base.

The Detroit Tigers have gotten 5 double plays and have a fielding rate of .971 (26th in professional baseball). The Tigers have recorded 49 assists, 6 errors and have accounted for 150 putouts on the campaign. Out of their 450 innings on the diamond, the Tigers hold a defensive efficiency of 70.0% (19th in professional baseball).

So far in his MLB career, Valdez has surrendered 919 base hits and he has 1,058 strikeouts in 1,086 frames. He has allowed a total of 405 earned runs while earning a WHIP of 1.205 and a FIP of 3.3. He has a strikeout to walk ratio of 2.71 and he has gone up against 4,508 hitters in his MLB career. Valdez (81-52 career win-loss mark) has earned a 3.36 earned run average while giving up 7.6 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Detroit (+132)

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