St. Louis Cardinals vs Milwaukee Brewers Prediction, 5/26/2026 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Milwaukee Brewers

Date: Tuesday, May 26, 2026

Location: American Family Field in Milwaukee, WI

TV: Brewers.TV

Odds/Point Spread: St. Louis (+106) Milwaukee (-128)

The Milwaukee Brewers (31-20) are hosting the St. Louis Cardinals (29-23) at American Family Field on Tuesday. The moneyline on this game has St. Louis at +106 and Milwaukee is sitting at -128. The over/under has been set at 8. The starting pitchers are Michael McGreevy and Kyle Harrison.

The Cardinals have recorded 74 doubles as a squad and have smacked 60 baseballs out of the park. St. Louis has a slugging rate of .393 and have been called out on strikes 412 times, while drawing a walk on 179 occasions. As a unit, the St. Louis Cardinals are putting up 4.6 runs per contest, which has them sitting at 11th in MLB. They have accumulated 226 runs batted in and 416 hits for the year, and their average at the plate comes in at .242. They have accumulated 233 runs while holding a team OBP of .323.

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Their strikeout to walk ratio is 2.00 and their pitching staff holds a collective WHIP of 1.37. Cardinals pitchers have yielded 55 home runs and also 232 runs in total (16th in the league). St. Louis has allowed 444 hits (8.6 per 9 innings) as well as 216 earned runs. The Cardinals have an ERA of 4.20 for the season (21st in the league), and the staff has struck out 380 hitters. Their pitching staff has walked 190 opposing players and their FIP sits at 4.38 as a unit on the season.

The Cardinals have dispatched 185 relievers to the hill this year. The relievers have inherited 81 base runners for the year and 32.1% of those runners crossing home plate. The bullpen have tallied 43 holds on the year (2nd in the league). Cardinals bullpen pitchers have stepped onto the hill with runners on base 58 times in addition to having 65 appearances in high leverage situations. They have compiled 17 saves for the season and have blown 9 of 26 chances to save the game. The Cardinals relief pitchers have earned a save rate of 65.4% and have come into the game in 71 save situations.

The St. Louis Cardinals have a total of 1,388 putouts on the year, as well as 496 assists and 23 errors. Their fielding percentage sits at .988 which has them sitting 9th in professional baseball, and have earned 52 double plays. The Cardinals have transformed 69.8% of baseballs in play into outs out of their 4,164 innings on the field, which has them sitting at 21st in pro baseball.

McGreevy has taken the hill for 174 frames and has tallied 113 punch outs in his MLB career. McGreevy (14-7 mark in his career) is the owner of a FIP of 3.41 while he has faced 703 hitters in the majors. His earned run average is 3.46 (67 earned runs allowed) and he has a WHIP of 1.113. He has allowed 160 base knocks (8.3 hits per nine innings) and has 34 walks.

Milwaukee has hit 34 home runs over the course of the season as well as 231 runs batted in. They have notched 82 two-baggers, while taking a walk 213 times as well as recording 246 runs. The Milwaukee Brewers have earned a team OBP of .333 as well as a team batting average of .246 this season. The Brewers hold a team slugging % of .361 and they are recording 4.92 runs per outing (4th in MLB). They have struck out on 393 occasions (27th in the league) and have recorded 413 hits.

The Brewers hold a team WHIP of 1.213 and have a FIP of 3.32 as a team so far this season. Their K/BB ratio comes in at 9.90 (488 strikeouts against 182 free passes). They are sitting at 1st in baseball as a pitching staff in total hits given up with 358. They have surrendered 37 home runs and they surrender 3.62 runs per 9 innings (4th in the league). The Milwaukee pitching staff have conceded 179 runs this year while holding an ERA of 3.32 (164 earned runs relinquished).

Milwaukee relievers have an inherited score percentage of 36.8% out of their 68 inherited base runners. Their relief pitchers have taken the field 48 times in high leverage situations in addition to 43 occasions with runners on. With 52 save situations, the Brewers have recorded 27 holds and also 8 blown saves. They sit at 13th in the league holding a save rate of 66.7%, and they have sent 156 relief pitchers onto the diamond on the year.

The Milwaukee Brewers have gotten 39 double plays and hold a fielding percentage of .987 (13th in the majors). The Brewers have accrued 381 assists, 22 errors and have a total of 1,336 putouts over the course of the season. Out of their 4,008 innings on the field, the Brewers have a efficiency on defense of 70.2% (19th in baseball).

During his pro baseball career, Harrison has given up 224 hits while earning 250 strikeouts in 239 innings pitched. Harrison (14-10 career win-loss mark) has earned a 3.91 ERA and has given up 8.4 hits per 9 innings. He has allowed 104 earned runs while earning a WHIP of 1.274 and having a FIP of 3.9. His K/BB ratio is 3.09 and he has gone up against 1,018 hitters in his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Milwaukee (-128)

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