St. Louis Cardinals vs New York Yankees Prediction, 8/5/2026 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs New York Yankees

Date: Wednesday, August 5, 2026

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: St. Louis (+132) New York (-160)

The St. Louis Cardinals (56-57) are traveling to Yankee Stadium on Wednesday where they will take on the New York Yankees (63-50). The odds on this game have St. Louis at +132 while New York is coming in at -160. The betting total comes in at 8. The starting pitchers are Andre Pallante and Will Warren.

The Cardinals have compiled 153 two-baggers as a team and have knocked 118 baseballs out of the park. St. Louis has a slugging % of .380 and have struck out 872 times, while drawing a walk on 365 occasions. As a team, the St. Louis Cardinals are knocking in 4.4 runs per game, which is 18th in baseball. They have 483 runs batted in in addition to 909 base knocks so far this season, while their average at the plate is sitting at .240. They have accounted for 496 runs while holding a team OBP of .315.

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Their K/BB ratio is 2.29 and their pitching staff has earned a collective WHIP of 1.34. Cardinals pitchers have conceded 112 long balls and also 506 runs in total (16th in baseball). St. Louis has surrendered 977 base knocks (8.7 per 9 innings) and 467 earned runs. The Cardinals have compiled a team ERA of 4.16 over the course of the season (16th in baseball), and their staff has struck out 865 hitters. They have walked 378 opposing batters and their FIP is 4.11 as a team for the season.

The Cardinals have sent 380 relief pitchers to the mound for the season. The relievers have inherited 179 base runners for the season and 37.4% of those players ended up scoring. The relief pitchers have recorded 71 holds on the year (6th in MLB). Cardinals pitchers have entered the contest with players on base 124 times and also have had 141 appearances in high leverage situations. They have compiled 31 saves for the year and have blown 21 out of their 52 save chances. The Cardinals bullpen have recorded a save rate of 59.6% and have come into the game in 126 save situations.

The St. Louis Cardinals have a tally of 3,028 putouts on the year, in addition to 1,059 assists and 49 errors. Their fielding percentage is holding at .988 which ranks 5th in professional baseball, and have a total of 103 double plays. The Cardinals have turned 69.3% of baseballs in play into outs in their 9,084 innings on the field, which has them sitting 21st in the majors.

Pallante has taken the hill for 578 innings and has totaled 407 strikeouts during his career. His earned run average is 4.20 (270 ER's allowed) and his WHIP is 1.378. He has conceded 583 hits (9.1 hits per nine innings) with 214 walks. Pallante (35-35 record in his career) has a FIP of 4.14 and he has gone up against 2,479 opposing hitters during his time in the majors.

The Yankees have a SLG% of .414 and they tally 4.59 runs per contest (11th in MLB). They have put up 167 two-baggers, while walking 409 times and putting up 519 runs. New York has hit 162 home runs this season to go along with 494 runs batted in. They have struck out on 1,031 instances (5th in the league) and are sitting with 872 base knocks. The New York Yankees have a team OBP of .310 and a batting average of .232 on the season.

The Yankees have a team WHIP of 1.188 and have a FIP of 3.71 as a unit on the campaign. They have a ranking of 3rd in baseball as a pitching staff in total hits surrendered with 848. The New York pitching staff have conceded 438 runs this season while having a team ERA of 3.37 (377 earned runs surrendered). They have earned a strikeout to walk ratio of 9.00 (1,012 strikeouts against 349 free passes). They have relinquished 112 long balls and they allow 3.91 runs per 9 innings (4th in the league).

They are currently ranked 16th in baseball with a save rate of 59.6%, and they have sent 380 relief pitchers onto the field this year. Their relievers have stepped onto the hill 133 times in high leverage situations and also on 136 occasions with runners on base. Sitting with 112 save situations, the Yankees have recorded 59 holds and also 21 blown saves. New York has called on relief pitchers to step onto the hill in 52 save chances and they have tallied 31 saves. New York relief pitchers hold an inherited score percentage of 23.1% of 199 inherited base runners.

The New York Yankees have gotten 84 double plays and hold a fielding percentage of .985 (16th in professional baseball). The Yankees have recorded 989 assists, 61 errors and have accounted for 3,023 putouts on the campaign. In their 9,069 innings played, the Yankees hold a defensive efficiency of 71.0% (7th in professional baseball).

In his career, Warren has surrendered 303 hits while he has accumulated 309 strikeouts in 293 innings pitched. Warren (17-16 career mark) holds a 4.79 earned run average while allowing 9.3 hits per 9 innings. He has conceded a total of 156 ER's while earning a WHIP of 1.412 and being the owner of a FIP of 4.7. He has a strikeout to walk ratio of 2.78 and he has gone up against 1,294 opposing batters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take St. Louis (+132)

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