St. Louis Cardinals vs Philadelphia Phillies Prediction, 8/22/2026 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Philadelphia Phillies

Date: Saturday, August 22, 2026

Location: Citizens Bank Park in Philadelphia, PA

TV: NBC Sports Philadelphia

Odds/Point Spread: St. Louis (+102) Philadelphia (-122)

The St. Louis Cardinals (66-63) are headed to Citizens Bank Park on Saturday where they will go up against the Philadelphia Phillies (70-58). The odds on this game have the Cardinals at +102 and the Phillies are at -122. The over/under is set at 9. The pitchers who are expected to start will be Andre Pallante and Andrew Painter.

St. Louis is slugging .382 and have been called out on strikes 999 times, while being walked on 425 occasions. They have amassed 557 RBI's as well as 1,040 hits for the year, while their team batting average is .241. The Cardinals have compiled 185 two-baggers as a squad and have knocked 133 baseballs out of the stadium. They have tallied 572 runs while holding a team on-base percentage of .317. As a squad, the St. Louis Cardinals are putting up 4.4 runs per game, which is 18th in MLB.

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The Cardinals are sitting with a team ERA of 4.04 for the season (12th in baseball), and their staff has rung up 1,000 hitters. Cardinals pitchers have given up 126 long balls and 562 runs in total (16th in baseball). They have walked 437 opposing hitters and their FIP comes in at 4.06 as a team on the campaign. St. Louis has allowed 1,089 base hits (8.5 per 9 innings) as well as 517 earned runs. They have earned a strikeout to walk ratio of 2.29 and their pitching staff holds a WHIP of 1.33.

The Cardinals have dispatched 430 relievers to the hill on the year. The relievers have inherited 198 base runners on the season and 38.4% of those runners ended up scoring. The relief pitchers have accumulated 85 holds so far this year (5th in MLB). Cardinals bullpen pitchers have stepped onto the hill with runners on 133 times as well as having 163 appearances in high leverage situations. They have earned 38 saves for the season and have blown 23 of 61 save opportunities. The Cardinals relievers have compiled a save rate of 62.3% and have entered the game in 150 save situations.

The Cardinals have turned 69.6% of balls hit into play into outs out of their 10,353 innings on the diamond, ranking them 18th in professional baseball. The St. Louis Cardinals have earned a total of 3,451 putouts for the season, in addition to 1,207 assists and 55 errors. Their fielding percentage sits at .988 which puts them in 4th in the majors, and have 127 double plays.

Pallante has pitched in 596 innings and has earned 418 strikeouts during his pro baseball career. His earned run average is 4.15 (275 earned runs allowed) and he has a WHIP of 1.378. He has conceded 600 hits (9.1 hits per nine innings) and has had 221 walks. Pallante (36-35 win-loss mark in his career) sits with a FIP of 4.09 while he has faced 2,547 opposing hitters during his time in the majors.

The Philadelphia Phillies have tallied an on-base percentage of .312 and a batting average of .241 this year. They have been called out on strikes on 1,080 occasions (15th in baseball) and are sitting with 1,033 base hits. Philadelphia has 155 long balls over the course of the season to go along with 555 runs batted in. The Phillies have a SLG% of .401 and they have an average of 4.48 runs per outing (16th in the league). They have put up 181 two-baggers, while getting a free base 411 times and putting up 574 runs.

The Phillies have a WHIP of 1.306 in addition to having a FIP of 3.77 as a staff for the season. They have earned a K/BB ratio of 10.00 (1,259 strikeouts against 392 walks). They rank 25th in MLB as a staff in total hits conceded with 1,091. They have conceded 150 long balls and they surrender 4.43 runs per 9 innings (15th in MLB). The Philadelphia pitching staff have allowed 559 runs this year while having an ERA of 4.12 (520 earned runs yielded).

Philadelphia relievers have an inherited score rate of 36.9% out of their 130 inherited runners. Their relief pitchers have come in 121 times in high leverage situations in addition to 97 occasions with runners on. With 109 save situations, the Phillies have 56 holds in addition to 16 blown saves. They rank 11th in MLB with a save rate of 68.6%, and they have dispatched 429 bullpen pitchers onto the diamond on the year.

The Philadelphia Phillies have gotten 77 double plays and hold a fielding percentage of .986 (15th in professional baseball). The Phillies have recorded 1,049 assists, 64 errors and are sitting with 3,407 putouts so far this season. In 10,221 innings played, the Phillies have accumulated a defensive efficiency of 67.4% (29th in professional baseball).

During his career, Painter has surrendered 98 base knocks while he has accumulated 71 K's in 85 innings. He has surrendered a total of 61 earned runs while earning a WHIP of 1.551 and having a FIP of 6.4. He has a strikeout to walk ratio of 2.09 and he has gone up against 383 opposing hitters so far in his MLB career. Painter (2-8 mark in his career) is the owner of a 6.45 ERA while surrendering 10.4 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Philadelphia (-122) and under 9 runs

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