Toronto Blue Jays vs Baltimore Orioles Prediction, 9/23/2026 MLB Picks, Best Bets & Odds
Game: Toronto Blue Jays vs Baltimore Orioles
Date: Wednesday, September 23, 2026
Location: Oriole Park at Camden Yards in Baltimore, MD
TV: MASN
Odds/Point Spread: Toronto (-152) Baltimore (+126)
Oriole Park at Camden Yards is the location where the Baltimore Orioles (76-81) will take on the Toronto Blue Jays (77-80) on Wednesday. The line on this matchup has Toronto at -152 while Baltimore is sitting at +126. The betting total is set at 8. The starting pitchers will be CJ Van Eyk and Trey Gibson.

Toronto has a slugging rate of .382 and have been called out on strikes 1,116 times, while being walked on 444 occasions. They have recorded 601 RBI's as well as 1,311 base knocks this year, while their team batting average sits at .248. The Blue Jays have accumulated 247 doubles as a squad and have smacked 149 baseballs out of the park. They are sitting with 632 runs scored while having a team OBP of .310. As a team, the Toronto Blue Jays are putting up 4.0 runs per game, which puts them at 29th in the league.
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They have accrued a K/BB ratio of 2.35 and their pitching staff has earned a collective WHIP of 1.30. Blue Jays pitchers have surrendered 163 home runs and 675 runs (11th in the league). Toronto has given up 1,231 base hits (8.0 per 9 innings) and also 606 earned runs. The Blue Jays have a team earned run average of 3.92 on the campaign (9th in baseball), and the staff has struck out 1,365 batters. They have walked 581 players from the other team and their FIP is 4.00 as a squad this season.
The Blue Jays relief pitchers have recorded a save rate of 75.0% and have entered the game in 177 save situations. They have accumulated 51 saves on the season and have blown 17 of their 68 save opportunities. The relief pitchers have inherited 247 base runners on the campaign with 25.9% of them crossing the plate. Blue Jays relief pitchers have stepped onto the hill with players on base 169 times as well as having 190 appearances in high leverage situations. The Blue Jays have sent 590 relievers to the mound for the year. The bullpen have racked up 104 holds so far this year (5th in MLB).
The Blue Jays have converted 70.1% of baseballs in play into outs in their 12,537 innings on the diamond, which ranks them 13th in pro baseball. The Toronto Blue Jays have amassed 4,179 putouts so far this season, in addition to 1,318 assists and 96 errors. Their fielding percentage is at .983 which has them ranked 25th in MLB, and have accumulated 106 double plays.
Van Eyk (0-1 career record) sits with a FIP of 4.29 and he has faced 35 hitters during his time in the major leagues. He has given up 11 hits (16.0 hits per nine innings) with 2 free passes. His ERA is 4.35 (3 ER's allowed) and his career WHIP is 2.097. Van Eyk has pitched in 6 innings and has accumulated 1 strikeouts during his pro baseball career.
The Baltimore Orioles have accumulated a team OBP of .314 as well as a team batting average of .234 on the campaign. They have been called out on strikes on 1,474 occasions (3rd in the league) and have recorded 1,224 hits. Baltimore has 192 home runs on the season as well as 672 RBIs. The Orioles have a team slugging % of .395 and they average 4.44 runs per contest (16th in the league). They have notched 229 two-baggers, while taking a walk 571 times and putting up 697 runs.
The Orioles have a team WHIP of 1.340 and are the owners of a FIP of 4.07 as a squad on the season. They currently have a strikeout to walk ratio of 8.20 (1,269 strikeouts vs 525 bases on balls). They are currently ranked 26th in the league as a pitching staff in total hits given up with 1,353. They have surrendered 168 dingers and they relinquish 4.67 runs per 9 innings (21st in MLB). The Baltimore pitching staff have given up 727 runs for the season and come in with a team ERA of 4.11 (640 earned runs relinquished).
With 150 save situations, the Orioles have 80 holds in addition to 22 blown saves. Baltimore has called on relief pitchers to step onto the mound in 67 save chances and they have walked away with 45 saves. Baltimore relievers have an inherited score percentage of 26.2% out of 221 inherited runners. Their relief pitchers have stepped onto the hill 169 times in high leverage situations and on 162 occasions with runners on. They are currently ranked 12th in the league holding a save rate of 67.2%, and they have sent 528 relief pitchers to the mound on the season.
The Baltimore Orioles have turned 119 double plays and have earned a fielding percentage of .984 (22nd in professional baseball). The Orioles have racked up 1,341 assists, 92 errors and have earned 4,204 putouts so far this year. In their 12,612 innings on the field, the Orioles have earned a defensive efficiency of 68.9% (27th in professional baseball).
Gibson (1-3 mark in his career) has a 7.36 ERA while giving up 10.4 hits per 9 innings. His K/BB ratio is 1.20 and he has gone up against 161 hitters so far in his career. He has conceded 27 earned runs while holding a WHIP of 1.909 and a FIP of 7.3. During his pro baseball career, Gibson has given up 38 base knocks while he has tallied 30 punch outs in 33 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Toronto (-152)
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Additional Resources:
Baltimore Orioles - Twitter
Toronto Blue Jays - Twitter
