Toronto Blue Jays vs Chicago Cubs Prediction, 6/21/2026 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs Chicago Cubs

Date: Sunday, June 21, 2026

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Toronto (-130) Chicago (+110)

The Chicago Cubs (40-36) will compete against the Toronto Blue Jays (37-39) at Wrigley Field on Sunday. The odds on this game have the Blue Jays at -130 while the Cubs are at +110. The total has been set at 8. The pitchers who are expected to start are Dylan Cease and Shota Imanaga.

Toronto has a slugging percentage of .391 and have been rung up 556 times, while taking a walk on 213 occasions. They have amassed 295 runs batted in as well as 634 hits for the year, while their average at the plate comes in at .249. The Blue Jays have accumulated 130 two-baggers as a team and have smacked 75 baseballs out of the stadium. They have tallied 308 runs scored and hold an on-base percentage of .312. As a unit, the Toronto Blue Jays are notching 4.1 runs per contest, which has them at 26th in the league.

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The Blue Jays are sitting with a team earned run average of 4.11 for the season (14th in the league), and the staff has rung up 670 hitters. Blue Jays pitchers have conceded 81 long balls and also 335 total runs (16th in baseball). They have walked 259 opposing hitters and their FIP sits at 3.92 as a team this year. Toronto has given up 615 hits (8.2 per 9 innings) in addition to 307 earned runs. They have earned a strikeout to walk ratio of 2.59 and the pitching staff holds a WHIP of 1.30.

The Blue Jays bullpen have earned a save rate of 67.6% and stepped onto the hill in 91 save situations. They have recorded 23 saves for the season and have not converted 11 of 34 save chances. The bullpen pitchers have inherited 123 runners on the season with 26.0% of them earned a run for their team. Blue Jays pitchers have come into the game with runners on base 87 times in addition to having 95 appearances in high leverage situations. The Blue Jays have dispatched 292 relievers to the hill for the year. The relief pitchers have recorded 55 holds this season (2nd in the league).

The Blue Jays have transformed 69.2% of balls in play into outs in their 6,054 innings, ranking them 23rd in professional baseball. The Toronto Blue Jays are sitting with 2,018 putouts thus far, in addition to 647 assists and 46 errors. Their fielding percentage is holding steady at .983 which has them ranked 22nd in professional baseball, and they have turned 52 double plays.

Cease has taken the hill for 1,088 innings and has earned 1,341 strikeouts during his career. Cease (69-61 record in his career) holds a FIP of 3.75 and he has gone up against 4,607 batters in the majors. His earned run average is 3.80 (460 earned runs allowed) and he has a career WHIP of 1.260. He has surrendered 910 base hits (7.5 hits per nine innings) and has had 461 free passes.

The Chicago Cubs have a team OBP of .336 and a team batting average of .243 on the season. They have struck out on 629 occasions (16th in MLB) and have earned 630 base hits. Chicago has accumulated 88 home runs so far this season as well as 333 RBIs. The Cubs have a team slugging % of .401 and they have an average of 4.74 runs per outing (8th in the league). They have 117 doubles, while getting a free base 331 times and scoring 360 runs.

The Chicago pitching staff have allowed 337 runs over the course of the season while holding a team ERA of 4.23 (317 earned runs conceded). They have conceded 111 homers and they concede 4.50 runs per 9 innings (16th in MLB). The Cubs have a WHIP of 1.240 in addition to having a FIP of 4.61 as a staff this year. Their strikeout to walk ratio sits at 8.00 (596 strikeouts against 230 bases on balls). They are currently ranked 14th in the league as a staff in total hits relinquished with 606.

They sit at 27th in baseball with a save rate of 50.0%, and they have sent 240 relievers to the hill on the year. Their relief pitchers have stepped onto the mound 69 times in high leverage situations and also on 74 occasions with runners on base. With 46 save situations, the Cubs have 21 holds and 11 blown saves. Chicago has called on relievers to enter the game in 22 save chances and they have converted 11 saves. Chicago relief pitchers have an inherited score rate of 29.5% of 105 inherited base runners.

In 6,069 innings played, the Cubs hold a defensive efficiency of 72.3% (2nd in professional baseball). The Chicago Cubs have turned 49 double plays and own a fielding percentage of .989 (6th in pro baseball). The Cubs have accrued 704 assists, 31 errors and have a total of 2,023 putouts during this campaign.

During his career, Imanaga has surrendered 336 base knocks while totaling 375 K's in 404 frames. Imanaga (28-17 record in his career) has a 3.50 ERA while allowing 7.5 hits per 9 innings. He has given up a total of 157 ER's while earning a WHIP of 1.019 and a FIP of 3.4. He has a K/BB ratio of 4.93 and he has gone up against 1,610 opposing batters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+110)

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