Toronto Blue Jays vs Cleveland Guardians Prediction, 9/2/2026 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs Cleveland Guardians

Date: Wednesday, September 2, 2026

Location: Progressive Field in Cleveland, OH

TV: MLB.TV

Odds/Point Spread: Toronto (-160) Cleveland (+132)

Progressive Field is the location where the Cleveland Guardians (69-68) will attempt to defeat the Toronto Blue Jays (68-70) on Wednesday. The moneyline on this contest has the Blue Jays at -160 and the Guardians are coming in at +132. The over/under is 8.5. The pitchers taking the mound are Dylan Cease and Joey Cantillo.

As a unit, the Toronto Blue Jays are knocking in 4.0 runs per contest, which ranks them 29th in the league. They have accounted for 548 runs and hold an on-base percentage of .307. The Blue Jays have accounted for 221 two-baggers as a team and have hit 131 balls out of the park. They have compiled 524 runs batted in as well as 1,142 hits on the season, while their team batting average comes in at .246. Toronto is slugging .382 and have struck out 990 times, while being walked on 381 occasions.

Get all of our MLB Expert Picks

The Blue Jays hold a team ERA of 3.94 so far this year (11th in baseball), and the staff has struck out 1,211 hitters. Blue Jays pitchers have relinquished 141 home runs and 598 total runs (12th in the league). They have walked 509 hitters and their FIP is 3.93 as a unit on the season. Toronto has allowed 1,094 base knocks (8.0 per 9 innings) and also 538 earned runs. Their strikeout to walk ratio is 2.38 and the pitching staff sits with a WHIP of 1.31.

The Blue Jays relievers have recorded a save percentage of 75.4% and have entered the game in 155 save situations. They have recorded 46 saves on the campaign and have blown 15 out of their 61 save opportunities. The relief pitchers have inherited 212 base runners so far this year and 26.9% of them crossing the plate. Blue Jays bullpen pitchers have stepped onto the hill with players on base 148 times in addition to having 175 appearances in high leverage situations. The Blue Jays have dispatched 512 relief pitchers to the hill for the year. The bullpen have a total of 90 holds over the course of the season (4th in baseball).

The Blue Jays have converted 69.8% of baseballs in play into outs out of their 11,055 innings on the field, which has them sitting at 14th in professional baseball. The Toronto Blue Jays are sitting with 3,685 putouts for the season, as well as 1,159 assists and 81 errors. Their fielding percentage sits at .984 which is 22nd in professional baseball, and have accumulated 92 double plays.

Cease has taken the hill for 1,165 frames and has accumulated 1,448 K's in his MLB career. Cease (74-63 record in his career) holds a FIP of 3.63 and he has gone up against 4,905 batters in the major leagues. His earned run average is 3.68 (477 earned runs allowed) and his WHIP is 1.238. He has conceded 947 hits (7.3 hits per nine innings) and has 495 free passes.

The Guardians hold a team slugging % of .371 and they are earning 4.07 runs per game (27th in baseball). They have hit 208 two-baggers, while walking 495 times and putting up 557 runs. Cleveland has accumulated 127 HRs over the course of the season and 534 RBIs. They have been called out on strikes on 1,108 instances (22nd in MLB) and have accounted for 1,081 hits. The Cleveland Guardians have recorded an on-base percentage of .315 as well as a batting average of .237 on the season.

The Guardians have a team WHIP of 1.259 and have a FIP of 3.89 as a squad this season. They come in at 9th in baseball as a pitching staff in total hits given up with 1,080. The Cleveland pitching staff have given up 559 runs for the season while holding a team ERA of 3.73 (504 earned runs relinquished). Their strikeout to walk ratio comes in at 9.40 (1,274 strikeouts against 450 bases on balls). They have allowed 154 homers and they relinquish 4.14 runs per 9 innings (7th in baseball).

Sitting with 156 save situations, the Guardians have earned 100 holds and also 14 blown saves. Cleveland has called on bullpen pitchers to enter the game in 54 save chances and they have converted 40 saves. Cleveland relievers have an inherited score percentage of 26.3% out of their 217 inherited base runners. Their relief pitchers have stepped onto the hill 151 times in high leverage situations and on 139 occasions with runners on. They rank 4th in MLB with a save percentage of 74.1%, and they have sent 470 relief pitchers onto the field on the year.

The Cleveland Guardians have gotten 89 double plays and have a fielding rate of .985 (17th in baseball). The Guardians have recorded 1,059 assists, 71 errors and have notched a total of 3,647 putouts this year. In their 10,941 innings played, the Guardians are sitting with a defensive efficiency of 69.6% (17th in pro baseball).

Cantillo (16-14 win-loss mark in his career) has a 3.70 ERA while surrendering 8.0 hits per 9 innings. He has a K/BB ratio of 2.34 and he has faced 1,153 opposing batters during his pro baseball career. He has given up 111 ER's while earning a WHIP of 1.362 and a FIP of 3.6. During his career, Cantillo has conceded 241 hits while totaling 297 K's in 270 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Toronto (-160)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.