Toronto Blue Jays vs Los Angeles Angels Prediction, 4/22/2026 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs Los Angeles Angels

Date: Wednesday, April 22, 2026

Location: Angel Stadium in Anaheim, CA

TV: FanDuel Sports Network West

Odds/Point Spread: Toronto (+126) Los Angeles (-152)

Angel Stadium is the site where the Los Angeles Angels (11-13) will take on the Toronto Blue Jays (9-13) on Wednesday. The line on this contest has the Blue Jays at +126 while the Angels are opening at -152. The total comes in at 8.5. The pitchers taking the mound are Eric Lauer and Jose Soriano.

Toronto has a slugging rate of .382 and have struck out 152 times, while drawing a walk on 66 occasions. They have tallied 86 RBI's and 190 hits for the year, while their team batting average sits at .253. The Blue Jays have hit 38 two-baggers as a team and have knocked 19 baseballs out of the park. They have a total of 88 runs scored while holding a team on-base percentage of .316. As a team, the Toronto Blue Jays are earning 4.0 runs/g, which ranks them 23rd in MLB.

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Their K/BB ratio is 2.97 and their pitching staff has recorded a WHIP of 1.31. Blue Jays pitchers have yielded 25 long balls in addition to 111 runs (23rd in the league). Toronto has allowed 182 hits (8.3 per 9 innings) and also 97 earned runs. The Blue Jays are sitting with a team ERA of 4.44 for the season (22nd in the league), and the staff has struck out 226 hitters. They have walked 76 players from the other team and their FIP sits at 3.75 as a team on the year.

Blue Jays relief pitchers have entered the contest with runners on base 28 times in addition to having 33 appearances in high leverage situations. The relief pitchers have tallied 14 holds for the year (15th in MLB). The Blue Jays relief pitchers have a save percentage of 30.0% and have come into the game in 26 save situations. They have recorded 3 saves so far this year and have blown 7 out of their 10 save opportunities. The relief pitchers have inherited 36 base runners on the season with 30.6% of those players ended up crossing the plate. The Blue Jays have dispatched 85 relievers to the hill on the year.

The Blue Jays have turned 67.0% of balls in play into outs out of their 1,770 innings, which has them ranked 28th in professional baseball. The Toronto Blue Jays have earned 590 putouts this year, as well as 179 assists and 17 errors. Their fielding rate is holding at .978 which puts them in 27th in the majors, and they have turned 15 double plays.

Lauer has taken the hill for 718 innings and has 685 punch outs so far in his pro baseball career. His earned run average is 4.21 (336 ER's allowed) and his career WHIP is 1.332. He has surrendered 691 base knocks (8.7 hits per nine innings) and has 266 free passes. Lauer (46-42 career record) sits with a FIP of 4.15 while going up against 3,082 opposing batters during his time in the major leagues.

The Los Angeles Angels have accounted for a team OBP of .331 and a batting average of .223 for the year. They have been called out on strikes on 241 instances (1st in MLB) and have tallied 176 hits. Los Angeles has 34 long balls over the course of the season and 113 RBIs. The Angels have a team SLG% of .390 and they earn 4.88 runs per contest (10th in the league). They have notched 28 doubles, while taking a walk 112 times as well as racking up 117 runs.

The Angels hold a team WHIP of 1.372 and have a FIP of 4.07 as a pitching staff for the season. They are sitting at 13th in the league as a pitching staff in total hits conceded with 174. The Los Angeles pitching staff have given up 109 runs so far this year while holding an ERA of 4.03 (95 earned runs conceded). Their K/BB ratio comes in at 9.30 (219 strikeouts against 117 walks). They have allowed 20 homers and they relinquish 4.63 runs per 9 innings (17th in baseball).

Los Angeles relief pitchers have an inherited score rate of 34.7% of 49 inherited runners. Their bullpen pitchers have stepped onto the hill 27 times in high leverage situations and on 33 occasions with base runners. With 22 save situations, the Angels have recorded 13 holds and 4 blown saves. They rank 23rd in the league holding a save percentage of 50.0%, and they have dispatched 70 relief pitchers to the hill this year.

The Los Angeles Angels have turned 13 double plays and hold a fielding percentage of .982 (23rd in pro baseball). The Angels have recorded 203 assists, 15 errors and have accumulated 637 putouts for the year. In 1,911 innings on the diamond, the Angels have accumulated a efficiency on defense of 70.8% (12th in pro baseball).

So far in his pro baseball career, Soriano has allowed 293 hits while he has earned 344 strikeouts in 356 innings pitched. Soriano (22-21 career record) has earned a 3.56 earned run average while conceding 7.4 hits per nine innings. He has given up a total of 141 ER's while earning a WHIP of 1.269 and a FIP of 3.5. His strikeout to walk ratio is 2.16 and he has gone up against 1,497 opposing hitters during his career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Toronto (+126)

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