Toronto Blue Jays vs New York Yankees Prediction, 5/21/2026 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs New York Yankees

Date: Thursday, May 21, 2026

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: Toronto (+132) New York (-160)

The Toronto Blue Jays (21-27) are hitting the road to Yankee Stadium on Thursday where they will take on the New York Yankees (30-19). The line on this contest has the Blue Jays at +132 while the Yankees are at -160. The total comes in at 9. The pitchers taking the mound are Spencer Miles and Carlos Rodon.

The Blue Jays have accrued 71 doubles as a squad and have knocked 44 baseballs out of the park. Toronto is slugging .371 and have struck out 331 times, while drawing a walk on 139 occasions. As a squad, the Toronto Blue Jays are notching 4.1 runs per contest, which is 23rd in MLB. They have earned 191 RBI's and 393 base knocks on the campaign, and their batting average comes in at .243. They have accumulated 198 runs and hold an on-base percentage of .306.

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The Blue Jays hold a team earned run average of 4.06 this year (14th in baseball), and the staff has struck out 433 batters. Blue Jays pitchers have surrendered 49 home runs and also 211 runs in total (13th in the league). They have walked 153 opposing hitters and their FIP is 3.76 as a unit this year. Toronto has allowed 401 hits (8.5 per 9 innings) and 192 earned runs. Their K/BB ratio is 2.83 and their pitching staff has recorded a WHIP of 1.30.

The Blue Jays have sent 180 relief pitchers to the mound so far this year. The relievers have inherited 77 base runners on the campaign and 23.4% of those runners earned a run for their team. The relievers have tallied 27 holds so far this year (16th in baseball). Blue Jays relief pitchers have gone to the mound with runners on base 57 times and also have had 56 appearances in high leverage situations. They have accumulated 9 saves this season and have blown 10 of 19 chances to save the game. The Blue Jays relievers have a save rate of 47.4% and have come into the game in 48 save situations.

The Toronto Blue Jays have accounted for 1,276 putouts over the course of the season, as well as 400 assists and 31 errors. Their fielding percentage is at .982 which has them sitting 27th in MLB, and they have turned 36 double plays. The Blue Jays have turned 67.9% of balls hit into play into outs in their 3,828 innings on the diamond, which has them sitting 27th in pro baseball.

Miles has taken the ball for 24 innings and is sitting with 23 strikeouts so far in his career. Miles (1-0 career mark) is the owner of a FIP of 2.56 while he has gone up against 100 batters in the major leagues. His earned run average is 2.60 (7 ER's allowed) and his career WHIP is 1.116. He has surrendered 20 base hits (7.4 hits per nine innings) and has had 7 free passes.

New York has knocked in 73 home runs so far this season as well as 236 RBIs. They have recorded 82 doubles, while walking 226 times and scoring 249 runs. The New York Yankees have an OBP of .333 and a batting average of .236 on the season. The Yankees have a team slugging percentage of .433 and they average 5.08 runs per game (4th in the league). They have been rung up on 436 occasions (8th in the league) and have earned 378 base hits.

The New York pitching staff have conceded 179 runs on the campaign while having a team ERA of 3.37 (162 earned runs yielded). They have allowed 39 homers and they concede 3.72 runs per 9 innings (4th in MLB). The Yankees have a WHIP of 1.175 and have a FIP of 3.49 as a squad this year. Their strikeout to walk ratio comes in at 8.90 (428 strikeouts against 151 free passes). They come in at 6th in the league as a staff in total hits conceded with 358.

Sitting with 54 save situations, the Yankees have compiled 32 holds in addition to 9 blown saves. New York has had relievers take the mound in 21 save chances and they have tallied 12 saves. New York relievers hold an inherited score rate of 30.3% out of their 89 inherited runners. Their relief pitchers have stepped onto the hill 56 times in high leverage situations and on 58 occasions with base runners. They sit at 23rd in baseball with a save rate of 57.1%, and they have sent 160 relievers to the hill over the course of the season.

Out of their 3,900 innings played, the Yankees are sitting with a defensive efficiency of 71.1% (8th in pro baseball). The New York Yankees have turned 35 double plays and own a fielding percentage of .986 (18th in pro baseball). The Yankees have recorded 465 assists, 25 errors and have a tally of 1,300 putouts for the season.

Rodon (93-73 mark in his career) has a 3.75 earned run average and has allowed 7.6 hits per nine innings. He has a strikeout to walk ratio of 2.93 and he has gone up against 5,416 batters so far in his career. He has surrendered 537 ER's while earning a WHIP of 1.221 and being the owner of a FIP of 3.7. In his career, Rodon has allowed 1,090 hits while he has earned 1,419 strikeouts in 1,290 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Toronto (+132)

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