Washington Nationals vs Chicago White Sox Prediction, 4/26/2026 MLB Picks, Best Bets & Odds

Game: Washington Nationals vs Chicago White Sox

Date: Sunday, April 26, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Washington (+132) Chicago (-160)

Rate Field is the site where the Chicago White Sox (10-15) will attempt to beat the Washington Nationals (11-15) on Sunday. The odds on this game have the Nationals at +132 and the White Sox are sitting at -160. The over/under has been set at 9. The pitchers taking the mound are Foster Griffin and Sean Burke.

Washington has a slugging rate of .410 and have been called out on strikes 218 times, while taking a walk on 93 occasions. They have 132 RBI's as well as 229 base knocks so far this season, while their average at the plate comes in at .252. The Nationals have hit 44 two-baggers as a team and have knocked 32 balls out of the stadium. They have 144 runs and have an OBP of .331. As a squad, the Washington Nationals are notching 5.5 runs per outing, which has them sitting at 3rd in the league.

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The Nationals have compiled a team ERA of 5.63 on the campaign (29th in the league), and their staff has struck out 200 hitters. Nationals pitchers have allowed 47 long balls and also 162 total runs (30th in MLB). Their pitching staff has walked 106 opposing batters and their FIP sits at 5.59 as a unit on the year. Washington has given up 253 base hits (9.7 per 9 innings) in addition to 147 earned runs. They have accrued a K/BB ratio of 1.89 and their pitching staff has earned a collective WHIP of 1.53.

Nationals relief pitchers have entered the contest with players on base 26 times as well as having 25 appearances in high leverage situations. The relievers have accumulated 13 holds on the campaign (18th in the league). The Nationals bullpen have compiled a save rate of 38.5% and stepped onto the hill in 30 save situations. They have compiled 5 saves for the season and have blown 8 out of their 13 save opportunities. The relievers have inherited 42 runners on the campaign and 47.6% of them earned a run for their team. The Nationals have dispatched 91 relievers to the mound on the year.

The Nationals have converted 68.2% of balls hit into play into outs out of their 2,115 innings, ranking them 23rd in baseball. The Washington Nationals have earned 705 putouts this year, in addition to 248 assists and 24 errors. Their fielding percentage is holding steady at .975 which has them ranked 30th in MLB, and have earned 21 double plays.

Griffin has taken the ball for 34 frames and has earned 27 punch outs during his MLB career. His ERA is 4.21 (16 earned runs allowed) and he has a WHIP of 1.287. He has surrendered 31 hits (8.2 hits per 9 innings) and has had 13 free passes. Griffin (4-0 win-loss record in his career) has earned a FIP of 4.15 while he has gone up against 149 hitters in the majors.

The Chicago White Sox hold an on-base percentage of .316 and a batting average of .224 on the campaign. They have been rung up on 234 occasions (7th in the league) and have totaled 186 base knocks. Chicago has compiled 32 home runs for the year as well as 95 runs batted in. The White Sox hold a team slugging percentage of .386 and they earn 4.16 runs per contest (20th in the league). They have 28 two-baggers, while walking 99 times as well as notching 104 runs.

The White Sox have a team WHIP of 1.487 and have a FIP of 4.66 as a staff this year. They are currently ranked 20th in baseball as a pitching staff in total hits given up with 209. The Chicago pitching staff have conceded 130 runs for the year while having an ERA of 4.97 (121 earned runs allowed). They currently have a K/BB ratio of 7.90 (192 strikeouts against 117 bases on balls). They have yielded 26 HR's and they relinquish 5.34 runs per 9 innings (27th in the league).

Chicago relievers have an inherited score rate of 34.6% out of 52 inherited base runners. Their bullpen pitchers have stepped onto the mound 27 times in high leverage situations and also on 32 occasions with runners on base. Sitting with 25 save situations, the White Sox have recorded 10 holds in addition to 8 blown saves. They are ranked 24th in baseball holding a save percentage of 46.7%, and they have dispatched 92 relievers onto the field so far this season.

The Chicago White Sox have turned 20 double plays and hold a fielding percentage of .984 (21st in professional baseball). The White Sox have racked up 222 assists, 14 errors and have amassed 659 putouts on the campaign. In 1,977 innings played, the White Sox have earned a defensive efficiency of 69.5% (20th in the majors).

In his MLB career, Burke has allowed 168 base knocks while accumulating 175 K's in 179 innings pitched. He has surrendered 78 ER's while earning a WHIP of 1.367 and having a FIP of 3.9. His K/BB ratio is 2.27 and he has gone up against 781 batters during his pro baseball career. Burke (7-13 record in his career) is the owner of a 3.92 earned run average and has given up 8.4 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Washington (+132)

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