Washington Nationals vs Cleveland Guardians Prediction, 5/25/2026 MLB Picks, Best Bets & Odds
Game: Washington Nationals vs Cleveland Guardians
Date: Monday, May 25, 2026
Location: Progressive Field in Cleveland, OH
TV: MLB.TV
Odds/Point Spread: Washington (+110) Cleveland (-130)
Progressive Field is the site where the Cleveland Guardians (31-23) will take on the Washington Nationals (26-27) on Monday. The moneyline on this game has the Nationals at +110 and the Guardians are priced at -130. The over/under is set at 8. The starting pitchers will be Zack Littell and Tanner Bibee.

As a team, the Washington Nationals are recording 5.4 runs per game, which is 1st in baseball. They have accumulated 286 runs scored while having a team OBP of .323. The Nationals have hit 104 doubles as a unit and have hit 65 balls out of the stadium. They have amassed 268 RBI's in addition to 445 hits this season, while their average at the plate is sitting at .243. Washington owns a slugging percentage of .416 and have struck out 450 times, while drawing a walk on 194 occasions.
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The Nationals hold a team earned run average of 4.87 over the course of the season (26th in baseball), and their staff has rung up 423 hitters. Nationals pitchers have conceded 76 long balls in addition to 301 runs in total (30th in the league). They have walked 191 players from the other team and their FIP is 4.79 as a squad so far this year. Washington has relinquished 477 base hits (8.9 per 9 innings) in addition to 260 earned runs. Their strikeout to walk ratio sits at 2.21 and their pitching staff has a collective WHIP of 1.39.
The Nationals have dispatched 174 relievers to the mound on the season. The relievers have inherited 70 runners this season and 48.6% of those players earned a run for their team. The relief pitchers have 26 holds this year (21st in baseball). Nationals pitchers have gone to the mound with runners on base 52 times as well as having 62 appearances in high leverage situations. They have recorded 15 saves on the season and have blown 14 of 29 save opportunities. The Nationals bullpen have a save percentage of 51.7% and have stepped onto the mound in 59 save situations.
The Washington Nationals have a tally of 1,442 putouts this year, as well as 470 assists and 49 errors. Their fielding percentage sits at .975 which has them sitting 30th in baseball, and they have turned 37 double plays. The Nationals have turned 69.0% of balls hit into play into outs out of their 4,326 innings, which ranks them 26th in baseball.
Littell (37-33 career mark) sits with a FIP of 3.97 while he has faced 2,722 hitters during his time in the major leagues. He has surrendered 649 base knocks (9.0 hits per 9 innings) with 150 free passes. His earned run average is 4.03 (290 ER's allowed) and his WHIP is 1.232. Littell has taken the mound for 648 frames and has tallied 519 K's in his career.
The Guardians hold a team slugging percentage of .372 and they average 4.24 runs per game (18th in the league). They have put up 85 two-baggers, while taking a walk 228 times and earning 229 runs. Cleveland has tallied 54 home runs for the year as well as 219 RBIs. They have struck out on 405 instances (26th in baseball) and have accounted for 400 base hits. The Cleveland Guardians have tallied a team OBP of .320 and a team batting average of .227 for the season.
The Guardians hold a team WHIP of 1.251 in addition to having a FIP of 3.85 as a pitching staff this year. They are currently ranked 16th in the league as a pitching staff in total hits conceded with 413. The Cleveland pitching staff have relinquished 208 runs for the year while holding a team ERA of 3.60 (191 earned runs surrendered). Their strikeout to walk ratio comes in at 9.50 (505 strikeouts vs 185 free passes). They have surrendered 59 home runs and they concede 3.92 runs per 9 innings (6th in the league).
Cleveland bullpen pitchers hold an inherited score rate of 25.0% out of their 80 inherited runners. Their relief pitchers have stepped onto the hill 62 times in high leverage situations and also on 50 occasions with base runners. With 70 save situations, the Guardians have accumulated 45 holds and also 4 blown saves. They rank 2nd in MLB with a save percentage of 83.3%, and they have dispatched 175 relievers to the mound for the year.
Out of their 4,305 innings played, the Guardians have accumulated a efficiency on defense of 70.4% (16th in MLB). The Cleveland Guardians have turned 40 double plays and have earned a fielding percentage of .989 (8th in pro baseball). The Guardians have 410 assists, 21 errors and are sitting with 1,435 putouts on the season.
Bibee (34-29 win-loss mark in his career) is the owner of a 3.63 earned run average while conceding 8.0 hits per 9 innings. He has a K/BB ratio of 3.30 and he has gone up against 2,307 hitters so far in his career. He has allowed 225 ER's while holding a WHIP of 1.183 and being the owner of a FIP of 3.6. So far in his pro baseball career, Bibee has allowed 496 hits while earning 542 punch outs in 558 frames.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Washington (+110)
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Additional Resources:
Cleveland Guardians - Twitter
Washington Nationals - Twitter
