Columbus Blue Jackets vs Buffalo Sabres Prediction, 11/6/2026 NHL Picks, Best Bets & Odds
Game: Columbus Blue Jackets vs Buffalo Sabres
Date: Friday, November 6, 2026
Location: KeyBank Center in Buffalo, NY
TV: Blue Jackets Hockey Network, MSG Network
Odds/Point Spread: Blue Jackets (+145) Sabres (-175)
KeyBank Center is the location where the Buffalo Sabres (7-5-3) will attempt to beat the Columbus Blue Jackets (6-7-0) on Friday. The moneyline on this game has Columbus at +145 and Buffalo is opening at -175. The over/under is set at 6.5.

The Columbus Blue Jackets were on the winning side of the scoreboard with a 7-2 win over the Avalanche in their previous contest . Columbus accounted for 6 penalty minutes for this game. The Blue Jackets had a good offensive performance and it was apparent in this victory. They also had 4 power play opportunities and notched 2 goals. For the matchup, they netted 7 out of the 24 shots they launched.
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In terms of scoring goals, the Columbus Blue Jackets have tallied 35 goals (32nd in pro hockey) over the course of the season and have given up 41. For the current season, they have recorded 12 points and their points percentage is .462. Columbus comes into the game with 35 power play chances and they have notched 6 goals out of those attempts, giving them a rate of 17.14%. When playing at even strength, the Blue Jackets have surrendered 30 goals while earning 29 of their own. Columbus has taken 331 shots and has a shooting percentage of 10.6%. The Blue Jackets thus far have had 354 shots attempted against them and hold a save percentage of .884. Columbus Blue Jackets opponents have tallied 40 power play opportunities (28th in professional hockey) and have tallied 11 goals in those chances.
The player in the crease for this game is Cam Talbot. Over the course of his career, Talbot has earned 298 quality starts and his quality starts percentage is .553. He has a save percentage of .911 during his 16 mins in the crease. Talbot has seen 16,360 shot attempts taken against him and has recorded 14,903 saves. Opponents have tallied 1,459 goals against Talbot in his NHL career and his goals against average is 2.71. He has earned an overall record of 282-206-53 and he was named the starter in 539 games. Talbot has been involved in 574 contests throughout his pro hockey career.
In their last game, Buffalo squared up with the Senators in a game where the Sabres ended up taking the loss by a final score of 2-1. They had 2 power play attempts in this contest but weren't able to put one in the back of the net. The Sabres tallied 1 goal out of the 24 shots on goal they pursued.
This season, the Buffalo Sabres have earned 44 goals, 17 points, and a points percentage of .567. They have granted a total of 50 goals to be scored by way of 34 goals at even strength and 16 goals while they were shorthanded. The Sabres are sitting with 36 goals at even strength and 8 goals (25th in hockey) while having more men on the ice. They have a tally of 49 power play chances and they have accumulated a power play rate of 16.33%. Buffalo has tried 417 shots (17th in the league) and has a shooting percentage of 10.55%, while allowing their opponents 409 shots. They have a penalty kill percentage of 69.81% on their opponents 53 tries on the power play, and their save percentage sits at 87.8%.
On the other side of the ice you are likely to see Ukko-Pekka Luukkonen defending the net. His opponents are averaging 2.94 goals per game and he has relinquished 571 goals in total. Luukkonen's percentage of quality starts is 53.6% and he has 104 quality starting assignments in his pro career. He got the starting nod in 194 games and has been on the ice for 10,935 minutes. Luukkonen has earned a career record of 97-77-21 and has been in net for 200 games. He has a tally of 5,062 stops out of the 5,631 shots tried, which gives him a rate of .899.
Who will win tonight's NHL game against the spread or moneyline?
Tony's Pick: Take Columbus (+145)
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Additional Resources:
Buffalo Sabres - Twitter
Columbus Blue Jackets - Twitter

