Ottawa Senators vs Buffalo Sabres Prediction, 11/4/2026 NHL Picks, Best Bets & Odds

Game: Ottawa Senators vs Buffalo Sabres

Date: Wednesday, November 4, 2026

Location: KeyBank Center in Buffalo, NY

TV: TSN5, MSG Network

Odds/Point Spread: Senators (+124) Sabres (-148)

KeyBank Center is where the Buffalo Sabres (7-4-3) will take on the Ottawa Senators (9-6-1) on Wednesday. The odds on this game have the Senators at +124 and the Sabres are sitting at -148. The total has been set at 6.5.

The Ottawa Senators will look to clean up some issues after taking a 6-3 loss to the Ducks in their last outing. Ottawa accumulated 25 penalty mins in this game. The Senators had a middle of the road showing in this defeat. In addition, they had 3 power play opportunities but weren't able to score a goal. In the game, they netted 3 out of the 22 shots they put on goal.

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With respect to their scoring, the Ottawa Senators have earned 50 goals (9th in the NHL) for the year and have allowed 51. For the season, they have recorded 19 points and their points percentage comes in at .594. Ottawa skates onto the rink with 65 power play chances and they have tallied 8 goals out of those chances, garnering them a percentage of 12.31%. While at even strength, the Senators have surrendered 35 goals while notching 42 themselves. Ottawa has taken 411 shots and is the owner of a shooting percentage of 12.2%. The Senators have seen 435 shots tried against them and hold a save percentage of .883. Ottawa Senators opponents have totaled 60 power play opportunities (2nd in the NHL) and have come away with 16 goals in those chances.

The man in net for this game is Samuel Ersson. For his career, Ersson has accrued 64 quality starts and his rate for quality starts is .467. His save percentage sits at .883 during his 343 minutes between the pipes. Ersson has seen 3,579 shots against him and he has 3,162 total saves. Opponents have tallied 417 goals against Ersson in his professional career and his average for goals against per game is 3.04. He has an overall record of 66-53-18 and he was named the starter in 137 games. Ersson has been in net for 150 games during his hockey career.

Their last time out, Buffalo played the Kings in a matchup where the Sabres earned a win by a tally of 3-2. They had 3 power play opportunities in this one and recorded 2 out of those attempts. The Sabres scored 3 goals out of the 31 shots on goal they were seeking.

The Sabres have racked up 35 goals at even strength and 8 goals (19th in the league) while on the power play. Buffalo has tried 393 shots (16th in pro hockey) and has a shooting percentage of 10.94%, while allowing the other team 379 shots. During this campaign, the Buffalo Sabres have a total of 43 goals, 17 points, and a points percentage of .607. They have granted a total of 48 goals to be scored by way of 32 goals at even strength and 16 goals while they had less men on the ice. They have recorded 47 power play chances and they have earned a power play rate of 17.02%. They have a penalty kill percentage of 68.63% on their oppositions 51 opportunities on the power play, and their save percentage sits at 87.3%.

Across the ice you are likely to see Ukko-Pekka Luukkonen in net. The opposition is averaging 2.94 goals per contest and he has given up 571 goals overall. Luukkonen's percentage of quality starts is 53.6% and he has made 104 quality starting assignments in his career. He has started in 194 games and has racked up 10,935 mins. Luukkonen is sitting with a career mark of 97-77-21 and has been in net for 200 games. He has racked up 5,062 saves out of the 5,631 shots attempted, giving him a save percentage of .899.

Who will win tonight's NHL game against the spread or moneyline?

Guy's Pick: Take Buffalo (-148)

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