Arizona Diamondbacks vs Milwaukee Brewers Prediction, 8/25/2025 MLB Picks, Best Bets & Odds

Game: Arizona Diamondbacks vs Milwaukee Brewers

Date: Monday, August 25, 2025

Location: American Family Field in Milwaukee, WI

TV: FanDuel Sports Network Wisconsin

Odds/Point Spread: Arizona (+150) Milwaukee (-182)

American Family Field is the site where the Milwaukee Brewers (80-48) will take on the Arizona Diamondbacks (62-66) on Monday. The odds on this game have Arizona at +150 and Milwaukee is coming in at -182. The over/under comes in at 9. The men taking the mound will be Eduardo Rodriguez and Jacob Misiorowski.

As a unit, the Arizona Diamondbacks are scoring 4.9 runs per contest, which has them sitting at 5th in the league. They have racked up 628 runs scored while holding a team OBP of .325. The Diamondbacks have recorded 221 two-baggers as a team and have knocked 178 balls out of the stadium. They have 613 runs batted in and 1,086 base knocks over the course of the season, while their team batting average comes in at .251. Arizona has a slugging % of .439 and have struck out 1,012 times, while being walked on 438 occasions.

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The Diamondbacks hold a team earned run average of 4.55 for the year (25th in baseball), and the staff has rung up 1,027 hitters. Diamondbacks pitchers have surrendered 157 home runs and also 623 runs in total (26th in MLB). They have walked 400 opposing players and their FIP is 4.30 as a squad this year. Arizona has allowed 1,117 hits (8.8 per 9 innings) and 575 earned runs. Their K/BB ratio is 2.57 and the pitching staff has a team WHIP of 1.33.

Diamondbacks pitchers have entered the contest with runners on 106 times as well as having 118 appearances in high leverage situations. The bullpen have racked up 64 holds so far this year (22nd in MLB). The Diamondbacks bullpen have accumulated a save percentage of 58.6% and stepped onto the hill in 126 save situations. They have compiled 34 saves on the campaign and have blown 24 of 58 save opportunities. The bullpen pitchers have inherited 136 runners over the course of the season with 31.6% of them crossed the plate. The Diamondbacks have dispatched 388 relievers to the hill on the season.

The Arizona Diamondbacks have notched a total of 3,414 putouts on the campaign, as well as 1,138 assists and 63 errors. Their fielding percentage is holding at .986 which is 17th in the majors, and have a total of 97 double plays. The Diamondbacks have converted 69.3% of balls in play into outs out of their 10,242 innings on the field, which ranks them 21st in the majors.

Rodriguez has thrown 1,266 innings and has totaled 1,269 strikeouts so far in his MLB career. His earned run average is 4.20 (591 earned runs allowed) and he has a WHIP of 1.331. He has given up 1,244 base hits (8.8 hits per 9 innings) with 441 walks. Rodriguez (90-64 career record) is the owner of a FIP of 4.14 while going up against 5,420 batters in the majors.

Milwaukee has accumulated 136 home runs so far this season and 610 RBIs. They have recorded 201 two-baggers, while taking a walk 446 times and racking up 657 runs. The Milwaukee Brewers have accounted for a team OBP of .332 and a team batting average of .258 this season. The Brewers hold a team slugging % of .404 and they are earning 5.13 runs per contest (3rd in MLB). They have been called out on strikes on 1,008 instances (24th in the league) and have tallied 1,119 hits.

The Milwaukee pitching staff have surrendered 492 runs for the season while holding an ERA of 3.56 (451 earned runs given up). They have given up 137 home runs and they relinquish 3.89 runs per 9 innings (4th in the league). The Brewers hold a team WHIP of 1.227 with a FIP of 3.97 as a team this year. They currently have a K/BB ratio of 8.80 (1,112 strikeouts vs 426 bases on balls). They are currently ranked 2nd in MLB as a pitching staff in total hits allowed with 972.

Sitting with 144 save situations, the Brewers have compiled 89 holds in addition to 14 blown saves. Milwaukee has had relievers take the mound in 51 save opportunities and they have come away with 37 saves. Their bullpen pitchers have taken the field 145 times in high leverage situations in addition to 113 occasions with runners on base. Milwaukee relievers have an inherited score percentage of 32.2% of 171 inherited base runners. They are currently ranked 3rd in baseball with a save rate of 72.5%, and they have sent 437 relievers to the mound on the campaign.

In 10,257 innings on the diamond, the Brewers have a efficiency on defense of 71.4% (4th in professional baseball). The Milwaukee Brewers have gotten 91 double plays and have notched a fielding percentage of .987 (9th in the majors). The Brewers have 1,034 assists, 58 errors and have accounted for 3,419 putouts this year.

Misiorowski (4-2 career mark) has a 4.24 ERA while allowing 5.4 hits per nine innings. His strikeout to walk ratio is 2.75 and he has gone up against 156 hitters during his career. He has surrendered 18 ER's while earning a WHIP of 1.126 and a FIP of 4.2. In his career, Misiorowski has surrendered 23 base knocks while he has earned 55 K's in 38 frames.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Arizona (+150)

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