Baltimore Orioles vs New York Yankees Prediction, 6/21/2025 MLB Picks, Best Bets & Odds

Game: Baltimore Orioles vs New York Yankees

Date: Saturday, June 21, 2025

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: Baltimore (+220) New York (-275)

The Baltimore Orioles (31-42) are hitting the road to Yankee Stadium on Saturday where they will play the New York Yankees (42-31). The line on this contest has the Orioles at +220 while the Yankees are coming in at -275. The total is 8.5. The pitchers who are expected to start are Zach Eflin and Clarke Schmidt.

As a team, the Baltimore Orioles are putting up 4.0 runs per game, which ranks them 24th in MLB. They have notched a total of 293 runs scored and have an OBP of .305. The Orioles have tallied 106 two-baggers as a unit and have knocked 86 baseballs out of the stadium. They have accounted for 274 runs batted in in addition to 586 hits for the year, while their batting average sits at .241. Baltimore has a slugging % of .398 and have been called out on strikes 644 times, while drawing a walk on 203 occasions.

Get all of our MLB Parlay Picks

The Orioles have compiled a team ERA of 4.98 for the year (27th in MLB), and their staff has rung up 598 batters. Orioles pitchers have conceded 101 home runs and 372 runs in total (25th in the league). Their pitching staff has walked 237 opposing players and their FIP is 4.47 as a squad on the season. Baltimore has relinquished 674 base hits (9.5 per 9 innings) in addition to 353 earned runs. They have earned a strikeout to walk ratio of 2.52 and their pitching staff has a collective WHIP of 1.43.

The Orioles relief pitchers have earned a save rate of 68.0% and have come into the game in 86 save situations. The relievers have inherited 117 base runners over the course of the season and 20.5% of those players ended up crossing the plate. Orioles bullpen pitchers have stepped onto the hill with runners on 87 times as well as having 72 appearances in high leverage situations. The Orioles have dispatched 256 relief pitchers to the mound this year. The relievers have notched 58 holds so far this year (2nd in MLB). They have recorded 17 saves this year and have blown 8 out of their 25 save chances.

The Orioles have turned 67.3% of baseballs in play into outs out of 5,745 innings, which has them sitting 29th in MLB. The Atlanta Braves have a total of 1,915 putouts at this point in the season, in addition to 644 assists and 38 errors. Their fielding percentage is currently at .985 which puts them in 21st in MLB, and they have turned 53 double plays.

Eflin has taken the mound for 1,060 innings and has earned 910 strikeouts so far in his MLB career. His ERA is 4.20 (495 earned runs allowed) and his career WHIP is 1.224. He has surrendered 1,081 hits (9.2 hits per 9 innings) with 217 free passes. Eflin (68-65 career record) has a FIP of 4.14 while he has gone up against 4,432 hitters during his time in the majors.

New York has a total of 111 long balls over the course of the season to go along with 358 runs batted in. They have put up 126 doubles, while getting a free base 290 times and putting up 372 runs. The New York Yankees have an OBP of .335 in addition to a batting average of .251 for the year. The Yankees hold a team slugging percentage of .446 and they are recording 5.10 runs per outing (3rd in baseball). They have been rung up on 646 occasions (6th in the league) and have accounted for 621 base knocks.

The Yankees hold a team WHIP of 1.191 and have a FIP of 3.61 as a pitching staff for the year. They are sitting at 2nd in MLB as a pitching staff in total hits given up with 528. The New York pitching staff have allowed 275 runs for the season while holding a team ERA of 3.53 (254 earned runs yielded). Their K/BB ratio sits at 9.40 (678 strikeouts against 243 bases on balls). They have conceded 71 homers and they surrender 3.82 runs per 9 innings (8th in MLB).

With 70 save situations, the Yankees have tallied 41 holds and 7 blown saves. New York has had relief pitchers step onto the mound in 28 save chances and they have walked away with 21 saves. Their relief pitchers have come in 70 times in high leverage situations in addition to 79 occasions with base runners. New York relievers hold an inherited score percentage of 22.6% out of 124 inherited runners. They are ranked 3rd in MLB with a save rate of 75.0%, and they have sent 236 bullpen pitchers onto the diamond so far this year.

Out of their 5,829 innings played, the Yankees have accumulated a defensive efficiency of 71.5% (5th in pro baseball). The New York Yankees have turned 44 double plays and have earned a fielding percentage of .987 (14th in MLB). The Yankees have 613 assists, 34 errors and have earned a total of 1,943 putouts on the season.

In his MLB career, Schmidt has surrendered 352 hits and he has 371 strikeouts in 376 innings pitched. Schmidt (22-23 win-loss record in his career) is the owner of a 3.83 ERA and has surrendered 8.4 hits per 9 innings. He has given up a total of 160 earned runs while holding a WHIP of 1.289 and being the owner of a FIP of 3.8. His strikeout to walk ratio is 2.79 and he has gone up against 1,607 opposing hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Baltimore (+220)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here