Baltimore Orioles vs New York Yankees Prediction, 9/26/2025 MLB Picks, Best Bets & Odds

Game: Baltimore Orioles vs New York Yankees

Date: Friday, September 26, 2025

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: Baltimore (+110) New York (-132)

The Baltimore Orioles (74-84) are headed to Yankee Stadium on Friday where they will take on the New York Yankees (90-68). The odds on this game have the Orioles at +110 and the Yankees are sitting at -132. The total has been set at 9. The expected starting pitchers are Trevor Rogers and Will Warren.

Baltimore is slugging .394 and have been called out on strikes 1,413 times, while taking a walk on 469 occasions. They have 631 runs batted in and 1,249 base knocks for the year, while their team batting average is at .236. The Orioles have hit 248 doubles as a squad and have hit 183 balls out of the park. They have accumulated 664 runs scored while having a team OBP of .305. As a unit, the Baltimore Orioles are putting up 4.2 runs per contest, which has them sitting at 23rd in baseball.

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They have accrued a K/BB ratio of 2.58 and the pitching staff has a collective WHIP of 1.36. Orioles pitchers have allowed 209 home runs and 766 runs in total (24th in MLB). Baltimore has yielded 1,396 hits (9.0 per 9 innings) and 711 earned runs. The Orioles have an ERA of 4.57 this season (24th in the league), and they have struck out 1,316 batters. They have walked 510 opposing players and their FIP is 4.39 as a squad so far this year.

Orioles pitchers have entered the contest with players on base 151 times and also have had 167 appearances in high leverage situations. The relievers have accumulated 105 holds this year (4th in the league). The Orioles relievers have earned a save percentage of 65.5% and have come into the game in 167 save situations. They have compiled 38 saves for the year and have blown 20 of 58 save opportunities. The bullpen pitchers have inherited 210 base runners so far this year and 26.7% of those players earned a run for their team. The Orioles have sent 529 relief pitchers to the mound so far this season.

The Orioles have turned 68.5% of balls in play into outs out of their 12,597 innings, which has them sitting 26th in pro baseball. The Atlanta Braves have a tally of 4,199 putouts so far this season, as well as 1,378 assists and 87 errors. Their fielding percentage is holding at .985 which puts them in 20th in pro baseball, and they have turned 118 double plays.

Rogers has taken the hill for 516 frames and has tallied 518 strikeouts thus far in his career. His earned run average is 3.75 (215 ER's allowed) and his career WHIP is 1.298. He has allowed 478 hits (8.3 hits per nine innings) with 192 free passes. Rogers (24-36 win-loss record in his career) has a FIP of 3.69 while he has gone up against 2,206 opposing batters in the majors.

New York has a total of 266 home runs this season as well as 798 runs batted in. They have 252 doubles, while taking a walk 621 times and scoring 827 runs. The New York Yankees have an OBP of .332 and a team batting average of .251 on the season. The Yankees hold a slugging percentage of .454 and they are scoring 5.23 runs per contest (1st in MLB). They have been called out on strikes on 1,429 instances (3rd in the league) and have accounted for 1,341 base hits.

The Yankees are sitting with a team WHIP of 1.256 in addition to having a FIP of 3.99 as a team on the season. Their K/BB ratio comes in at 9.00 (1,401 strikeouts against 544 free passes). They are currently ranked 4th in MLB as a pitching staff in total hits surrendered with 1,219. They have allowed 169 home runs and they surrender 4.33 runs per 9 innings (14th in baseball). The New York pitching staff have given up 675 runs on the season while holding an ERA of 3.94 (615 earned runs conceded).

New York has had bullpen pitchers step onto the mound in 62 save chances and they have come away with 41 saves. They are ranked 7th in the league with a save rate of 66.1%, and they have dispatched 520 relievers to the hill this year. Their relief pitchers have come in 160 times in high leverage situations and also on 166 occasions with runners on. New York bullpen pitchers have an inherited score percentage of 27.8% out of 252 inherited runners. Sitting with 159 save situations, the Yankees have amassed 95 holds and 21 blown saves.

The New York Yankees have turned 105 double plays and own a fielding percentage of .984 (25th in pro baseball). The Yankees have recorded 1,361 assists, 92 errors and have accounted for 4,211 putouts on the campaign. In their 12,633 innings played, the Yankees have accumulated a defensive efficiency of 70.5% (10th in baseball).

During his pro baseball career, Warren has conceded 185 hits while earning 193 K's in 179 frames. Warren (8-11 career win-loss record) has earned a 5.12 ERA and has allowed 9.3 hits per nine innings. He has conceded 102 ER's while holding a WHIP of 1.445 and being the owner of a FIP of 5.0. His K/BB ratio is 2.61 and he has gone up against 799 batters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Baltimore (+110)

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