Boston Red Sox vs Houston Astros Prediction, 8/12/2025 MLB Picks, Best Bets & Odds

Game: Boston Red Sox vs Houston Astros

Date: Tuesday, August 12, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Boston (+220) Houston (-275)

Daikin Park is the location where the Houston Astros (66-52) will try to beat the Boston Red Sox (65-54) on Tuesday. The odds on this game have the Red Sox at +220 and the Astros are priced at -275. The over/under has been set at 9. The pitchers who are expected to start will be Dustin May and Spencer Arrighetti.

As a unit, the Boston Red Sox are knocking in 5.0 runs/g, which is 5th in the league. They have 593 runs scored and hold an on-base percentage of .324. The Red Sox have hit 244 two-baggers as a squad and have hit 143 balls out of the stadium. They have compiled 567 RBI's as well as 1,034 hits so far this year, and their average at the plate is .253. Boston owns a slugging percentage of .428 and have been called out on strikes 1,065 times, while taking a walk on 384 occasions.

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They have accrued a K/BB ratio of 2.46 and the pitching staff has a collective WHIP of 1.30. Red Sox pitchers have given up 119 long balls and also 509 total runs (15th in MLB). Boston has given up 990 base hits (8.4 per 9 innings) as well as 442 earned runs. The Red Sox hold a team ERA of 3.73 for the year (9th in baseball), and they have rung up 980 hitters. They have walked 399 batters and their FIP sits at 4.00 as a team so far this season.

The Red Sox bullpen have recorded a save rate of 59.3% and have stepped onto the mound in 120 save situations. The bullpen pitchers have inherited 163 base runners over the course of the season and 30.7% of them ended up crossing the plate. Red Sox bullpen pitchers have come into the game with opponents on base 121 times as well as having 145 appearances in high leverage situations. The Red Sox have sent 390 relievers to the mound on the season. The relievers have tallied 64 holds so far this year (19th in baseball). They have compiled 32 saves so far this season and have blown 22 of their 54 chances to save the game.

The Baltimore Orioles have accumulated 3,198 putouts over the course of the season, as well as 1,090 assists and 93 errors. Their fielding percentage is currently at .979 which puts them in 29th in the majors, and have a total of 98 double plays. The Red Sox have converted 68.9% of balls in play into outs out of their 9,594 innings, which ranks them 23rd in MLB.

May has taken the ball for 298 innings and has totaled 275 strikeouts so far in his career. His earned run average is 3.77 (125 ER's allowed) and he has a career WHIP of 1.166. He has given up 247 base hits (7.4 hits per 9 innings) and has had 101 walks. May (18-17 career mark) has earned a FIP of 3.71 while he has gone up against 1,243 batters during his time in the major leagues.

The Astros have a team SLG% of .408 and they have an average of 4.35 runs per game (15th in MLB). They have notched 186 doubles, while getting a free base 344 times as well as notching 513 runs. Houston has hit 131 HRs on the year and 491 RBIs. They have struck out on 922 occasions (24th in the league) and have 1,034 hits. The Houston Astros are sitting with a team OBP of .323 and a team batting average of .258 on the season.

The Astros hold a team WHIP of 1.192 and are the owners of a FIP of 3.79 as a team on the year. They have a ranking of 3rd in MLB as a pitching staff in total hits given up with 897. The Houston pitching staff have allowed 459 runs on the year while having a team ERA of 3.69 (430 earned runs yielded). Their strikeout to walk ratio is 9.70 (1,125 strikeouts against 353 walks). They have given up 136 home runs and they allow 3.94 runs per 9 innings (5th in the league).

Houston has called on relief pitchers to step onto the mound in 46 save chances and they have earned 34 saves. They rank 1st in the league holding a save rate of 73.9%, and they have sent 366 relief pitchers onto the field on the season. Their relief pitchers have taken the field 117 times in high leverage situations in addition to 84 occasions with runners on. Houston relievers hold an inherited score percentage of 25.9% of 116 inherited runners. Sitting with 117 save situations, the Astros have earned 69 holds and also 12 blown saves.

In 9,441 innings on the field, the Astros hold a efficiency on defense of 70.7% (11th in MLB). The Houston Astros have turned 74 double plays and have notched a fielding percentage of .988 (7th in professional baseball). The Astros have 919 assists, 48 errors and have accumulated 3,147 putouts this year.

In his career, Arrighetti has allowed 154 base knocks while he has tallied 184 punch outs in 158 innings pitched. Arrighetti (8-15 career record) is the owner of a 4.78 ERA while giving up 8.8 hits per 9 innings. He has surrendered 84 ER's while holding a WHIP of 1.423 and a FIP of 4.7. He has a strikeout to walk ratio of 2.59 and he has gone up against 694 opposing hitters during his career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (-275)

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