Boston Red Sox vs Philadelphia Phillies Prediction, 7/22/2025 MLB Picks, Best Bets & Odds
Game: Boston Red Sox vs Philadelphia Phillies
Date: Tuesday, July 22, 2025
Location: Citizens Bank Park in Philadelphia, PA
TV: NBC Sports Philadelphia
Odds/Point Spread: Boston (+110) Philadelphia (-130)
Citizens Bank Park is the location where the Philadelphia Phillies (56-43) will try to defeat the Boston Red Sox (54-47) on Tuesday. The line on this matchup has the Red Sox at +110 while the Phillies are at -130. The total has been set at 8.5. The pitchers expected to start will be Richard Fitts and Cristopher Sanchez.


As a squad, the Boston Red Sox are compiling 4.9 runs per game, which puts them at 5th in the league. They have tallied 498 runs while holding a team OBP of .325. The Red Sox have accrued 203 two-baggers as a squad and have knocked 125 baseballs out of the stadium. They have tallied 477 RBI's and 883 hits on the year, and their average at the plate is .254. Boston has a slugging % of .430 and have struck out 904 times, while being walked on 329 occasions.
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The Red Sox are sitting with a team earned run average of 3.79 for the year (11th in MLB), and their staff has struck out 842 hitters. Red Sox pitchers have surrendered 97 home runs and 441 total runs (21st in baseball). Their pitching staff has walked 331 players from the other team and their FIP comes in at 3.86 as a team so far this year. Boston has conceded 841 base hits (8.4 per 9 innings) and also 381 earned runs. They have earned a strikeout to walk ratio of 2.54 and their pitching staff holds a WHIP of 1.30.
Red Sox relief pitchers have come into the game with runners on 99 times and also have had 122 appearances in high leverage situations. The relief pitchers have earned 53 holds on the season (18th in MLB). The Red Sox bullpen have recorded a save rate of 59.1% and have entered the game in 99 save situations. They have accumulated 26 saves on the campaign and have missed out on 18 out of their 44 save opportunities. The relievers have inherited 135 base runners for the year with 34.1% of those runners crossed the plate. The Red Sox have sent 325 relievers to the mound this year.
The Red Sox have turned 68.5% of balls hit into play into outs out of their 7,908 innings, which ranks them 25th in pro baseball. The Baltimore Orioles have earned 2,636 putouts over the course of the season, as well as 908 assists and 78 errors. Their fielding rate is holding at .978 which has them ranked 29th in pro baseball, and have 82 double plays.
Fitts has thrown 53 innings and has 37 punch outs so far in his career. Fitts (1-4 career win-loss mark) has earned a FIP of 3.32 while going up against 228 batters in the major leagues. His ERA is 3.37 (20 earned runs allowed) and his career WHIP is 1.255. He has conceded 50 base hits (8.4 hits per nine innings) and has had 17 free passes.
The Phillies hold a slugging percentage of .405 and they are scoring 4.59 runs per game (11th in MLB). They have put up 157 two-baggers, while walking 343 times as well as scoring 454 runs. Philadelphia has accounted for 108 home runs this season as well as 432 RBIs. They have struck out on 786 occasions (21st in the league) and have accounted for 855 base hits. The Philadelphia Phillies have a team on-base percentage of .328 as well as a batting average of .255 so far this year.
The Phillies hold a team WHIP of 1.265 and have a FIP of 3.62 as a squad so far this year. They come in at 17th in the league as a pitching staff in total hits given up with 824. The Philadelphia pitching staff have yielded 394 runs on the campaign while having an ERA of 3.73 (365 earned runs conceded). Their K/BB ratio comes in at 9.30 (908 strikeouts vs 289 bases on balls). They have relinquished 102 dingers and they give up 4.03 runs per 9 innings (8th in baseball).
Philadelphia relief pitchers hold an inherited score percentage of 34.0% out of 94 inherited runners. Their relief pitchers have come in 102 times in high leverage situations and on 63 occasions with runners on. Sitting with 90 save situations, the Phillies have tallied 45 holds and also 17 blown saves. They sit at 17th in baseball holding a save percentage of 61.4%, and they have sent 305 relief pitchers onto the diamond over the course of the season. Philadelphia has had relievers step onto the hill in 44 save chances and they have tallied 27 saves.
The Philadelphia Phillies have turned 66 double plays and hold a fielding percentage of .989 (4th in baseball). The Phillies have 831 assists, 36 errors and have a tally of 2,560 putouts on the campaign. In 7,680 innings on the diamond, the Phillies hold a defensive efficiency of 68.9% (23rd in pro baseball).
In his career, Sanchez has given up 423 base hits while he has accumulated 419 punch outs in 448 innings pitched. Sanchez (25-18 career win-loss record) has earned a 3.39 ERA and has conceded 8.5 hits per nine innings. He has given up a total of 169 earned runs while holding a WHIP of 1.203 and a FIP of 3.3. He has a K/BB ratio of 3.61 and he has faced 1,856 opposing batters so far in his career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Boston (+110)
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Additional Resources:
Philadelphia Phillies - Twitter
Boston Red Sox - Twitter