Chicago Cubs vs Los Angeles Angels Prediction, 8/22/2025 MLB Picks, Best Bets & Odds

Game: Chicago Cubs vs Los Angeles Angels

Date: Friday, August 22, 2025

Location: Angel Stadium in Anaheim, CA

TV: FanDuel Sports Network West

Odds/Point Spread: Chicago (-152) Los Angeles (+126)

Angel Stadium is the location where the Los Angeles Angels (61-66) will go up against the Chicago Cubs (73-54) on Friday. The moneyline on this matchup has Chicago at -152 and Los Angeles is coming in at +126. The total is 9. The pitchers who are expected to start will be Ben Brown and Tyler Anderson.

As a team, the Chicago Cubs are compiling 5.0 runs per outing, which puts them at 5th in MLB. They have notched a total of 614 runs scored while having a team on-base percentage of .319. The Cubs have tallied 204 two-baggers as a team and have hit 170 baseballs out of the park. They have accumulated 598 RBI's as well as 1,059 base knocks on the year, and their team batting average is at .250. Chicago has a slugging % of .429 and have been called out on strikes 958 times, while taking a walk on 416 occasions.

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The Cubs have compiled a team earned run average of 3.83 on the season (11th in MLB), and they have struck out 945 hitters. Cubs pitchers have relinquished 153 long balls and also 504 runs (6th in MLB). They have walked 320 opposing players and their FIP comes in at 4.19 as a team for the year. Chicago has surrendered 1,007 base knocks (8.2 per 9 innings) and 469 earned runs. They have accumulated a K/BB ratio of 2.95 and their pitching staff has a team WHIP of 1.21.

The Cubs have dispatched 405 relievers to the mound for the year. The bullpen pitchers have inherited 118 base runners this year and 29.7% of them crossed home plate. They have accumulated 29 saves so far this year and have not converted 14 out of their 43 save opportunities. The Cubs relief pitchers have accumulated a save rate of 67.4% and have come into the game in 124 save situations. The bullpen have a total of 78 holds this year (8th in MLB). Cubs pitchers have stepped onto the hill with runners on 83 times as well as having 118 appearances in high leverage situations.

The Cubs have turned 71.4% of baseballs in play into outs in their 9,906 innings on the field, which has them sitting at 4th in MLB. The Boston Red Sox have a total of 3,302 putouts this season, as well as 1,037 assists and 52 errors. Their fielding percentage is currently at .988 which has them sitting 7th in MLB, and have earned 95 double plays.

Brown has taken the hill for 154 innings and has earned 172 K's thus far in his career. His earned run average is 5.08 (87 ER's allowed) and he has a WHIP of 1.324. He has surrendered 155 hits (9.1 hits per nine innings) and has 49 walks. Brown (6-10 career record) has earned a FIP of 5.00 and he has faced 662 hitters in the major leagues.

Los Angeles has compiled 176 HRs this year as well as 534 runs batted in. They have tallied 174 two-baggers, while taking a walk 388 times as well as putting up 552 runs. The Los Angeles Angels have accumulated an OBP of .307 as well as a team batting average of .233 so far this year. The Angels have a team slugging % of .407 and they average 4.42 runs per game (15th in the league). They have struck out on 1,220 occasions (1st in MLB) and have earned a total of 974 base hits.

The Angels have a WHIP of 1.434 with a FIP of 4.75 as a pitching staff for the season. They currently have a K/BB ratio of 8.10 (992 strikeouts against 480 walks). They rank 27th in the league as a staff in total hits allowed with 1,110. They have allowed 173 home runs and they relinquish 5.08 runs per 9 innings (27th in MLB). The Los Angeles pitching staff have conceded 626 runs so far this season while having an ERA of 4.69 (578 earned runs conceded).

Los Angeles has had bullpen pitchers take the mound in 57 save opportunities and they have tallied 29 saves. They are ranked 29th in the league holding a save rate of 50.9%, and they have dispatched 432 relievers onto the field for the season. Their relievers have stepped onto the mound 166 times in high leverage situations in addition to 120 occasions with base runners. Los Angeles bullpen pitchers hold an inherited score percentage of 37.0% out of their 181 inherited runners. Sitting with 128 save situations, the Angels have earned 68 holds and 28 blown saves.

The Los Angeles Angels have gotten 128 double plays and have a fielding rate of .984 (25th in the majors). The Angels have recorded 1,101 assists, 74 errors and have notched a total of 3,327 putouts this season. In 9,981 innings played, the Angels hold a defensive efficiency of 68.8% (26th in the majors).

In his career, Anderson has surrendered 1,209 base knocks and he has 1,039 strikeouts in 1,248 innings pitched. Anderson (62-72 career record) has earned a 4.32 ERA while conceding 8.7 hits per 9 innings. He has allowed 599 ER's while earning a WHIP of 1.297 and having a FIP of 4.3. His strikeout to walk ratio is 2.53 and he has gone up against 5,304 hitters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (-152)

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