Chicago White Sox vs Baltimore Orioles Prediction, 6/1/2025 MLB Picks, Best Bets & Odds
Game: Chicago White Sox vs Baltimore Orioles
Date: Sunday, June 1, 2025
Location: Oriole Park at Camden Yards in Baltimore, MD
TV: MASN
Odds/Point Spread: Chicago (+125) Baltimore (-150)
The Baltimore Orioles (19-36) welcome the Chicago White Sox (18-38) at Oriole Park at Camden Yards on Sunday. The line on this contest has the White Sox at +125 while the Orioles are at -150. The betting total is set at 8.5. The pitchers taking the mound are Adrian Houser and Charlie Morton.


The White Sox have tallied 83 doubles as a unit and have hit 46 baseballs out of the stadium. Chicago is slugging .344 and have struck out 470 times, while drawing a walk on 181 occasions. As a unit, the Chicago White Sox are notching 3.5 runs per game, which ranks them 26th in baseball. They have tallied 190 RBI's and 404 base knocks over the course of the season, and their batting average is at .221. They have accumulated 196 runs scored and hold an OBP of .294.
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The White Sox are sitting with a team earned run average of 4.13 this year (23rd in the league), and their staff has rung up 405 batters. White Sox pitchers have given up 59 home runs and also 244 runs in total (20th in baseball). They have walked 213 opposing hitters and their FIP sits at 4.55 as a unit so far this season. Chicago has yielded 451 base hits (8.4 per 9 innings) as well as 221 earned runs. They have earned a strikeout to walk ratio of 1.90 and their pitching staff has earned a collective WHIP of 1.38.
White Sox pitchers have entered the game with runners on 58 times and also have had 51 appearances in high leverage situations. The relievers have earned 28 holds so far this season (23rd in baseball). The White Sox relievers have accumulated a save rate of 31.3% and have entered the game in 44 save situations. They have compiled 5 saves so far this year and have blown 11 out of their 16 save opportunities. The relief pitchers have inherited 84 base runners so far this season and 31.0% of those players crossed the plate. The White Sox have sent 182 relief pitchers to the hill over the course of the season.
The Chicago Cubs have accumulated 1,445 putouts this season, as well as 454 assists and 40 errors. Their fielding percentage is holding steady at .979 which is 28th in professional baseball, and they have turned 42 double plays. The White Sox have transformed 70.0% of balls in play into outs out of their 4,335 innings, which ranks them 13th in professional baseball.
Houser has taken the hill for 620 innings and is sitting with 492 punch outs thus far in his career. His earned run average is 4.14 (285 ER's allowed) and he has a WHIP of 1.366. He has conceded 599 hits (8.7 hits per nine innings) and has 248 free passes. Houser (33-39 mark in his career) has a FIP of 4.07 and he has faced 2,662 opposing hitters in the majors.
The Baltimore Orioles are sitting with an OBP of .303 and a team batting average of .237 this year. They have struck out on 493 occasions (6th in the league) and have tallied 437 hits. Baltimore has accounted for 60 home runs this season to go along with 200 runs batted in. The Orioles have a slugging percentage of .386 and they score 3.87 runs per contest (25th in MLB). They have tallied 80 doubles, while walking 157 times and earning 213 runs.
The Baltimore pitching staff have surrendered 310 runs on the year while having an ERA of 5.49 (293 earned runs conceded). They have conceded 87 home runs and they relinquish 5.81 runs per 9 innings (28th in MLB). The Orioles have a WHIP of 1.481 and have a FIP of 4.96 as a squad for the year. Their strikeout to walk ratio is 8.00 (427 strikeouts vs 191 walks). They rank 28th in MLB as a staff in total hits conceded with 520.
Sitting with 52 save situations, the Orioles have tallied 32 holds and also 8 blown saves. Baltimore has called on relief pitchers to take the mound in 17 save opportunities and they have walked away with 9 saves. Their bullpen pitchers have stepped onto the mound 53 times in high leverage situations and on 70 occasions with runners on. Baltimore relief pitchers have an inherited score percentage of 25.6% out of their 90 inherited runners. They are ranked 24th in MLB holding a save rate of 52.9%, and they have sent 193 bullpen pitchers to the hill for the year.
In 4,323 innings on the field, the Orioles are sitting with a defensive efficiency of 67.7% (28th in pro baseball). The Baltimore Orioles have gotten 39 double plays and hold a fielding percentage of .984 (22nd in baseball). The Orioles have accrued 496 assists, 31 errors and have notched a total of 1,441 putouts for the season.
So far in his MLB career, Morton has conceded 2,043 hits and he has 2,092 K's in 2,172 frames. He has allowed 985 ER's while holding a WHIP of 1.315 and having a FIP of 4.0. His strikeout to walk ratio is 2.57 and he has gone up against 9,320 hitters in his MLB career. Morton (139-130 career record) is the owner of a 4.08 ERA and has conceded 8.5 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Chicago (+125)
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Additional Resources:
Baltimore Orioles - Twitter
Chicago White Sox - Twitter