Chicago White Sox vs Tampa Bay Rays Prediction, 7/22/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Tampa Bay Rays

Date: Tuesday, July 22, 2025

Location: George M. Steinbrenner Field in Tampa, FL

TV: FanDuel Sports Network Sun

Odds/Point Spread: Chicago (+220) Tampa Bay (-275)

The Chicago White Sox (35-65) are on their way to George M. Steinbrenner Field on Tuesday where they will try to beat the Tampa Bay Rays (52-48). The line on this contest has Chicago at +220 while Tampa Bay is coming in at -275. The total is set at 8.5. The expected starting pitchers will be Davis Martin and Drew Rasmussen.

As a team, the Chicago White Sox are putting up 3.6 runs per game, which has them at 27th in the league. They have earned a total of 359 runs scored while holding a team on-base percentage of .298. The White Sox have earned 160 two-baggers as a team and have smacked 80 baseballs out of the park. They have accumulated 344 runs batted in as well as 728 hits on the campaign, and their batting average is sitting at .223. Chicago has a slugging rate of .351 and have been called out on strikes 853 times, while being walked on 331 occasions.

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The White Sox hold a team earned run average of 4.07 this year (19th in the league), and the staff has rung up 720 batters. White Sox pitchers have conceded 106 home runs in addition to 437 runs in total (19th in the league). Their pitching staff has walked 361 opposing hitters and their FIP is 4.45 as a unit on the campaign. Chicago has yielded 832 hits (8.6 per 9 innings) as well as 394 earned runs. They have accrued a K/BB ratio of 1.99 and the pitching staff sits with a WHIP of 1.37.

The White Sox have sent 311 relief pitchers to the mound for the season. The relief pitchers have inherited 125 base runners over the course of the season with 28.0% of them crossed home plate. They have recorded 12 saves this year and have blown 16 of 28 save opportunities. The White Sox relievers have accumulated a save rate of 42.9% and have stepped onto the mound in 70 save situations. The relievers have tallied 42 holds on the campaign (27th in the league). White Sox relief pitchers have entered the contest with runners on 87 times in addition to having 88 appearances in high leverage situations.

The Chicago Cubs have amassed 2,531 putouts at this point in the season, as well as 799 assists and 58 errors. Their fielding percentage is holding at .983 which is 25th in MLB, and they have turned 81 double plays. The White Sox have converted 69.9% of balls hit into play into outs out of 7,593 innings, which has them sitting at 17th in professional baseball.

Martin has taken the ball for 193 innings and has racked up 148 K's so far in his MLB career. Martin (5-18 career win-loss record) has earned a FIP of 4.22 while he has faced 823 batters in the major leagues. His ERA is 4.28 (92 earned runs allowed) and he has a WHIP of 1.314. He has conceded 193 base knocks (9.0 hits per nine innings) and has had 61 free passes.

Tampa Bay is sitting with 110 home runs so far this year as well as 440 runs batted in. They have hit 154 doubles, while getting a free base 297 times and scoring 467 runs. The Tampa Bay Rays have recorded a team on-base percentage of .320 and a batting average of .258 so far this season. The Rays hold a slugging percentage of .406 and they score 4.67 runs per game (9th in baseball). They have been called out on strikes on 820 instances (16th in baseball) and have 870 hits.

The Rays hold a team WHIP of 1.198 and are the owners of a FIP of 4.21 as a squad over the course of the season. They are currently ranked 10th in MLB as a pitching staff in total hits given up with 787. The Tampa Bay pitching staff have conceded 397 runs so far this season while holding a team ERA of 3.76 (371 earned runs given up). Their strikeout to walk ratio sits at 8.40 (826 strikeouts vs 278 bases on balls). They have conceded 130 long balls and they concede 4.02 runs per 9 innings (7th in MLB).

With 93 save situations, the Rays have earned 54 holds in addition to 16 blown saves. Tampa Bay has had relief pitchers take the mound in 38 save opportunities and they have come away with 22 saves. Their relievers have stepped onto the mound 92 times in high leverage situations and also on 71 occasions with runners on. Tampa Bay relievers have an inherited score percentage of 36.9% out of 103 inherited base runners. They rank 22nd in baseball with a save rate of 57.9%, and they have sent 308 relievers to the hill on the year.

Out of their 7,764 innings played, the Rays have earned a defensive efficiency of 71.4% (5th in pro baseball). The Tampa Bay Rays have turned 97 double plays and have accounted for a fielding rate of .987 (12th in the majors). The Rays have accrued 887 assists, 46 errors and have earned 2,588 putouts during this campaign.

Rasmussen (27-17 career win-loss mark) is the owner of a 2.94 ERA and has conceded 7.4 hits per nine innings. He has a strikeout to walk ratio of 3.63 and he has faced 1,610 batters thus far in his career. He has allowed 131 earned runs while earning a WHIP of 1.077 and being the owner of a FIP of 2.9. During his MLB career, Rasmussen has allowed 328 hits while tallying 378 K's in 401 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Tampa Bay (-275)

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