Cincinnati Reds vs Chicago Cubs Prediction, 8/5/2025 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs Chicago Cubs

Date: Tuesday, August 5, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Cincinnati (+110) Chicago (-132)

The Chicago Cubs (65-46) will play the Cincinnati Reds (58-54) at Wrigley Field on Tuesday. The moneyline on this game has the Reds at +110 while the Cubs are sitting at -132. The total is set at 8. The starting pitchers will be Zack Littell and Shota Imanaga.

The Reds have earned 173 doubles as a team and have hit 115 balls out of the stadium. Cincinnati has a slugging % of .393 and have been called out on strikes 958 times, while taking a walk on 379 occasions. As a team, the Cincinnati Reds are earning 4.6 runs per outing, which ranks them 10th in the league. They have tallied 481 RBI's and 928 hits this season, and their batting average comes in at .247. They have a total of 512 runs scored and have an OBP of .321.

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The Reds hold a team earned run average of 3.89 for the season (15th in the league), and the staff has struck out 932 batters. Reds pitchers have conceded 124 home runs and 470 total runs (14th in baseball). They have walked 353 players from the other team and their FIP comes in at 4.06 as a team so far this year. Cincinnati has conceded 879 base hits (8.0 per 9 innings) in addition to 428 earned runs. They have a strikeout to walk ratio of 2.64 and the pitching staff holds a collective WHIP of 1.24.

The Reds relievers have a save percentage of 65.9% and have stepped onto the mound in 113 save situations. The relief pitchers have inherited 151 base runners so far this year with 34.4% of those players crossed the plate. Reds bullpen pitchers have entered the contest with runners on 95 times in addition to having 102 appearances in high leverage situations. The Reds have sent 381 relievers to the hill so far this season. The relievers are sitting with 70 holds so far this season (9th in the league). They have accumulated 27 saves for the season and have missed out on 14 of their 41 chances to save the game.

The Chicago White Sox have a tally of 2,972 putouts on the year, as well as 837 assists and 58 errors. Their fielding percentage is holding steady at .985 which puts them in 19th in MLB, and have a total of 67 double plays. The Reds have transformed 71.0% of balls hit into play into outs out of their 8,916 innings, which has them sitting at 8th in the majors.

Littell has taken the ball for 549 frames and has accounted for 455 K's in his MLB career. Littell (32-29 career win-loss mark) has a FIP of 3.78 while he has gone up against 2,292 opposing hitters during his time in the major leagues. His ERA is 3.84 (234 ER's allowed) and his WHIP is 1.229. He has given up 551 base hits (9.0 hits per 9 innings) and has 124 walks.

The Chicago Cubs have tallied a team OBP of .324 and a team batting average of .255 so far this season. They have struck out on 867 occasions (27th in baseball) and have 974 base hits. Chicago has compiled 159 home runs this year to go along with 564 RBIs. The Cubs have a slugging percentage of .441 and they have an average of 5.22 runs per outing (1st in MLB). They have notched 193 two-baggers, while taking a walk 378 times as well as scoring 579 runs.

The Cubs have a WHIP of 1.228 and are the owners of a FIP of 4.29 as a squad this year. They rank 17th in MLB as a staff in total hits allowed with 918. The Chicago pitching staff have surrendered 464 runs on the season while holding an ERA of 3.92 (430 earned runs conceded). They currently have a strikeout to walk ratio of 7.60 (831 strikeouts vs 294 bases on balls). They have conceded 142 dingers and they yield 4.23 runs per 9 innings (12th in the league).

Chicago has called on bullpen pitchers to step onto the mound in 39 save chances and they have earned 26 saves. They are currently ranked 7th in baseball holding a save percentage of 66.7%, and they have dispatched 367 bullpen pitchers onto the diamond for the year. Their bullpen pitchers have taken the field 108 times in high leverage situations and on 76 occasions with runners on base. Chicago bullpen pitchers have an inherited score rate of 31.1% of 106 inherited base runners. With 115 save situations, the Cubs have recorded 73 holds and also 13 blown saves.

The Chicago Cubs have turned 89 double plays and have a fielding rate of .988 (5th in the majors). The Cubs have 933 assists, 46 errors and are sitting with 2,963 putouts during this campaign. In 8,889 innings played, the Cubs have earned a efficiency on defense of 71.3% (4th in pro baseball).

So far in his career, Imanaga has surrendered 218 hits while he has totaled 237 punch outs in 256 innings. He has given up 86 earned runs while holding a WHIP of 1.027 and a FIP of 3.0. He has a strikeout to walk ratio of 5.27 and he has gone up against 1,026 opposing batters so far in his MLB career. Imanaga (23-7 mark in his career) has a 3.02 earned run average and has surrendered 7.7 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Cincinnati (+110)

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