Cincinnati Reds vs San Diego Padres Prediction, 9/9/2025 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs San Diego Padres

Date: Tuesday, September 9, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Cincinnati (+150) San Diego (-182)

The San Diego Padres (78-65) will go up against the Cincinnati Reds (72-71) at Petco Park on Tuesday. The line on this contest has the Reds at +150 and the Padres are coming in at -182. The over/under has been set at 9. The pitchers who are expected to start are Zack Littell and Michael King.

Cincinnati owns a slugging percentage of .392 and have struck out 1,243 times, while being walked on 470 occasions. They have 611 runs batted in in addition to 1,192 base knocks for the year, while their average at the plate comes in at .248. The Reds have hit 232 doubles as a squad and have knocked 141 balls out of the park. They have notched a total of 647 runs and hold an on-base percentage of .318. As a squad, the Cincinnati Reds are scoring 4.5 runs per game, which has them at 13th in baseball.

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The Reds have a team ERA of 3.94 on the year (16th in baseball), and their staff has rung up 1,217 hitters. Reds pitchers have allowed 170 long balls and 617 total runs (15th in MLB). Their pitching staff has walked 449 opposing batters and their FIP is 4.16 as a team this season. Cincinnati has allowed 1,133 base hits (8.1 per 9 innings) as well as 554 earned runs. They have accumulated a K/BB ratio of 2.71 and the pitching staff has recorded a WHIP of 1.25.

The Reds have sent 489 relief pitchers to the mound on the campaign. The bullpen pitchers have inherited 191 runners over the course of the season and 32.5% of those runners crossed the plate. They have compiled 33 saves for the year and have missed out on 20 out of their 53 save opportunities. The Reds relievers have accumulated a save rate of 62.3% and have stepped onto the mound in 145 save situations. The relief pitchers have 90 holds for the season (7th in baseball). Reds relief pitchers have stepped onto the hill with players on base 128 times in addition to having 145 appearances in high leverage situations.

The Reds have transformed 70.7% of baseballs in play into outs out of their 11,400 innings, ranking them 7th in baseball. The Chicago White Sox have 3,800 putouts so far this season, as well as 1,082 assists and 82 errors. Their fielding percentage is holding steady at .983 which ranks 26th in the majors, and have 92 double plays.

Littell has taken the ball for 581 innings and has tallied 482 punch outs thus far in his career. Littell (33-29 career record) has earned a FIP of 3.83 while he has faced 2,431 hitters during his time in the majors. His ERA is 3.89 (251 ER's allowed) and he has a career WHIP of 1.230. He has allowed 584 hits (9.0 hits per nine innings) and has 131 walks.

The Padres hold a team slugging % of .388 and they earn 4.27 runs per game (20th in MLB). They have hit 234 two-baggers, while getting a free base 461 times as well as scoring 610 runs. San Diego has hit 127 HRs over the course of the season to go along with 573 RBIs. They have been rung up on 1,015 occasions (28th in MLB) and have recorded 1,211 base hits. The San Diego Padres hold an on-base percentage of .323 and a team batting average of .253 over the course of the season.

The Padres have a team WHIP of 1.216 in addition to having a FIP of 4.02 as a team this season. Their strikeout to walk ratio sits at 8.80 (1,232 strikeouts vs 474 bases on balls). They are currently ranked 1st in baseball as a pitching staff in total hits relinquished with 1,061. They have surrendered 152 long balls and they relinquish 3.97 runs per 9 innings (4th in the league). The San Diego pitching staff have given up 556 runs for the season and come in with a team ERA of 3.67 (514 earned runs relinquished).

San Diego relievers have an inherited score percentage of 29.0% out of 231 inherited runners. Their relief pitchers have taken the field 186 times in high leverage situations in addition to 162 occasions with runners on. Sitting with 155 save situations, the Padres have 91 holds and 15 blown saves. They are ranked 1st in the league with a save rate of 74.6%, and they have dispatched 504 bullpen pitchers onto the diamond for the year. San Diego has had relief pitchers step onto the hill in 59 save opportunities and they have tallied 44 saves.

In 11,358 innings on the field, the Padres have a defensive efficiency of 71.7% (2nd in pro baseball). The San Diego Padres have gotten 105 double plays and have notched a fielding percentage of .987 (13th in pro baseball). The Padres have accrued 1,081 assists, 66 errors and are sitting with 3,786 putouts this season.

During his MLB career, King has allowed 400 base hits while totaling 548 strikeouts in 478 innings pitched. King (30-28 record in his career) has earned a 3.16 ERA while allowing 7.5 hits per nine innings. He has surrendered 168 ER's while holding a WHIP of 1.181 and having a FIP of 3.1. His strikeout to walk ratio is 3.32 and he has faced 1,997 opposing batters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cincinnati (+150)

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