Cleveland Guardians vs Boston Red Sox Prediction, 9/3/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Boston Red Sox

Date: Wednesday, September 3, 2025

Location: Fenway Park in Boston, MA

TV: NESN

Odds/Point Spread: Cleveland (+162) Boston (-196)

Fenway Park is the site where the Boston Red Sox (77-62) will attempt to defeat the Cleveland Guardians (68-68) on Wednesday. The moneyline on this contest has Cleveland at +162 while Boston is priced at -196. The total is set at 9. The pitchers who are expected to start will be Logan Allen and Kyle Harrison.

The Guardians have accumulated 194 doubles as a unit and have knocked 138 baseballs out of the park. Cleveland has a slugging rate of .366 and have struck out 1,123 times, while taking a walk on 416 occasions. As a team, the Cleveland Guardians are recording 3.9 runs per outing, which has them sitting at 28th in MLB. They have accumulated 504 runs batted in and 990 hits so far this season, while their average at the plate is at .223. They have notched a total of 523 runs scored and have an on-base percentage of .294.

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The Guardians have an ERA of 3.94 on the campaign (16th in the league), and their staff has rung up 1,128 batters. Guardians pitchers have given up 150 home runs and also 580 runs (12th in the league). They have walked 475 players from the other team and their FIP sits at 4.17 as a team so far this year. Cleveland has surrendered 1,115 base hits (8.3 per 9 innings) as well as 529 earned runs. Their strikeout to walk ratio sits at 2.37 and their pitching staff has recorded a WHIP of 1.32.

The Guardians relief pitchers have earned a save percentage of 68.4% and have come into the game in 152 save situations. The relief pitchers have inherited 177 runners for the season and 33.3% of those players ended up crossing the plate. Guardians relief pitchers have stepped onto the hill with players on base 125 times as well as having 156 appearances in high leverage situations. The Guardians have dispatched 451 relievers to the hill this year. The bullpen are sitting with 92 holds on the campaign (3rd in the league). They have earned 39 saves so far this season and have blown 18 of their 57 chances to save the game.

The Guardians have turned 69.5% of balls hit into play into outs out of 10,881 innings on the diamond, ranking them 19th in MLB. The Cincinnati Reds have earned 3,627 putouts thus far, as well as 1,114 assists and 86 errors. Their fielding rate is at .982 which has them ranked 27th in baseball, and have accumulated 102 double plays.

Allen has thrown 356 frames and has earned 303 punch outs in his pro baseball career. His earned run average is 4.57 (181 earned runs allowed) and he has a career WHIP of 1.465. He has surrendered 376 hits (9.5 hits per nine innings) with 146 walks. Allen (22-23 win-loss record in his career) is the owner of a FIP of 4.50 and he has faced 1,552 hitters during his time in the major leagues.

Boston has 167 long balls for the year as well as 652 runs batted in. They have hit 276 two-baggers, while getting a free base 454 times and putting up 684 runs. The Boston Red Sox hold an OBP of .325 as well as a batting average of .253 on the campaign. The Red Sox have a team SLG% of .425 and they score 4.92 runs per game (6th in the league). They have struck out on 1,224 instances (5th in baseball) and have earned a total of 1,206 base hits.

The Red Sox have a team WHIP of 1.287 in addition to having a FIP of 4.01 as a team over the course of the season. Their K/BB ratio is 8.30 (1,154 strikeouts vs 459 bases on balls). They come in at 18th in MLB as a staff in total hits relinquished with 1,143. They have conceded 140 dingers and they yield 4.19 runs per 9 innings (9th in MLB). The Boston pitching staff have conceded 580 runs on the year while having an ERA of 3.69 (510 earned runs yielded).

With 142 save situations, the Red Sox have tallied 76 holds and 24 blown saves. Boston has had bullpen pitchers enter the game in 64 save chances and they have recorded 40 saves. Their relievers have come in 167 times in high leverage situations in addition to 137 occasions with base runners. Boston relievers hold an inherited score percentage of 32.1% out of their 184 inherited runners. They sit at 16th in baseball with a save percentage of 62.5%, and they have dispatched 455 relief pitchers to the hill for the season.

The Boston Red Sox have gotten 113 double plays and own a fielding percentage of .980 (29th in pro baseball). The Red Sox have recorded 1,272 assists, 103 errors and have a tally of 3,735 putouts on the campaign. In 11,205 innings on the diamond, the Red Sox have a defensive efficiency of 69.2% (21st in baseball).

In his pro baseball career, Harrison has conceded 175 base knocks while he has tallied 178 K's in 182 frames. Harrison (9-9 win-loss mark in his career) is the owner of a 4.50 ERA and has allowed 8.6 hits per nine innings. He has conceded a total of 91 earned runs while earning a WHIP of 1.301 and being the owner of a FIP of 4.4. His strikeout to walk ratio is 2.87 and he has faced 779 batters thus far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Boston (-196)

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