Cleveland Guardians vs Chicago White Sox Prediction, 7/11/2025 MLB Picks, Best Bets & Odds
Game: Cleveland Guardians vs Chicago White Sox
Date: Friday, July 11, 2025
Location: Rate Field in Chicago, IL
TV: Chicago Sports Network
Odds/Point Spread: Cleveland (-122) Chicago (+102)
The Cleveland Guardians (41-48) are en route to Rate Field on Friday where they will try to beat the Chicago White Sox (30-61). The odds on this game have the Guardians at -122 while the White Sox are opening at +102. The total has been set at 9. The pitchers taking the mound are Gavin Williams and Shane Smith.


Cleveland has a slugging % of .363 and have been called out on strikes 731 times, while being walked on 274 occasions. They have amassed 304 runs batted in as well as 651 hits so far this season, and their average at the plate is sitting at .224. The Guardians have accumulated 126 two-baggers as a team and have hit 87 balls out of the park. They have accounted for 319 runs scored and have an OBP of .295. As a squad, the Cleveland Guardians are notching 3.6 runs/g, which is 26th in MLB.
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The Guardians are sitting with a team ERA of 3.97 this year (18th in baseball), and their staff has rung up 741 batters. Guardians pitchers have allowed 95 home runs in addition to 376 total runs (15th in baseball). Their pitching staff has walked 327 players from the other team and their FIP comes in at 4.14 as a squad for the year. Cleveland has conceded 739 hits (8.5 per 9 innings) in addition to 347 earned runs. They have earned a K/BB ratio of 2.27 and the pitching staff has earned a collective WHIP of 1.36.
Guardians pitchers have come into the game with runners on base 75 times in addition to having 89 appearances in high leverage situations. The relief pitchers have a total of 61 holds on the campaign (4th in the league). The Guardians relievers have accumulated a save rate of 72.7% and have come into the game in 95 save situations. They have recorded 24 saves so far this season and have blown 9 out of their 33 save chances. The relief pitchers have inherited 108 runners so far this year and 37.0% of those runners crossed home plate. The Guardians have dispatched 298 relievers to the hill this year.
The Guardians have transformed 68.6% of balls in play into outs in their 7,074 innings, ranking them 24th in MLB. The Cincinnati Reds have a tally of 2,358 putouts this season, in addition to 714 assists and 65 errors. Their fielding percentage sits at .979 which puts them in 28th in baseball, and have a total of 68 double plays.
Williams (11-19 win-loss record in his career) is the owner of a FIP of 3.83 while facing 1,074 opposing batters during his time in the majors. He has conceded 216 hits (7.8 hits per nine innings) and has 121 walks. His ERA is 3.89 (108 ER's allowed) and he has a career WHIP of 1.347. Williams has taken the ball for 250 frames and is sitting with 250 strikeouts thus far in his career.
The Chicago White Sox have a team OBP of .296 and a team batting average of .222 so far this year. They have struck out on 781 occasions (10th in MLB) and have accounted for 662 base knocks. Chicago has accounted for 70 home runs so far this year as well as 300 runs batted in. The White Sox hold a slugging percentage of .345 and they score 3.46 runs per contest (28th in baseball). They have tallied 138 doubles, while taking a walk 299 times and racking up 315 runs.
The Chicago pitching staff have conceded 403 runs this year while having a team ERA of 4.14 (363 earned runs conceded). They have conceded 99 dingers and they allow 4.60 runs per 9 innings (22nd in baseball). The White Sox hold a team WHIP of 1.389 and have a FIP of 4.52 as a staff for the season. Their K/BB ratio is 7.40 (652 strikeouts vs 332 walks). They sit at 20th in baseball as a pitching staff in total hits conceded with 764.
Chicago relievers have an inherited score percentage of 28.9% out of their 121 inherited base runners. Their relief pitchers have stepped onto the hill 80 times in high leverage situations in addition to 83 occasions with runners on. Sitting with 67 save situations, the White Sox have tallied 41 holds in addition to 15 blown saves. They rank 30th in baseball with a save rate of 42.3%, and they have dispatched 283 relief pitchers onto the diamond on the year. Chicago has had bullpen pitchers step onto the mound in 26 save opportunities and they have earned 11 saves.
The Chicago White Sox have gotten 77 double plays and have a fielding rate of .983 (25th in MLB). The White Sox have recorded 750 assists, 54 errors and have a total of 2,367 putouts over the course of the season. In 7,101 innings on the field, the White Sox are sitting with a defensive efficiency of 69.7% (19th in MLB).
So far in his MLB career, Smith has surrendered 74 hits while tallying 76 punch outs in 83 frames. He has conceded a total of 39 ER's while holding a WHIP of 1.334 and being the owner of a FIP of 4.2. He has a strikeout to walk ratio of 2.05 and he has faced 366 batters during his MLB career. Smith (3-7 career record) has earned a 4.22 earned run average while giving up 8.0 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Chicago (+102)
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Additional Resources:
Chicago White Sox - Twitter
Cleveland Guardians - Twitter