Cleveland Guardians vs Cincinnati Reds Prediction, 5/17/2025 MLB Picks, Best Bets & Odds
Game: Cleveland Guardians vs Cincinnati Reds
Date: Saturday, May 17, 2025
Location: Great American Ball Park in Cincinnati, OH
TV: FanDuel Sports Network Ohio
Odds/Point Spread: Cleveland (-210) Cincinnati (+172)
The Cleveland Guardians (25-18) are hitting the road to Great American Ball Park on Saturday where they will play the Cincinnati Reds (20-24). The moneyline on this game has Cleveland at -210 while Cincinnati is priced at +172. The betting total comes in at 8. The pitchers who are expected to start will be Luis Ortiz and Chase Petty.


The Guardians have tallied 56 doubles as a team and have smacked 48 balls out of the stadium. Cleveland has a slugging % of .381 and have been rung up 341 times, while drawing a walk on 142 occasions. As a squad, the Cleveland Guardians are recording 4.1 runs per game, which puts them at 20th in baseball. They have earned 165 runs batted in as well as 324 base knocks this year, and their average at the plate is at .233. They have tallied 176 runs while having a team OBP of .308.
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Their K/BB ratio is 2.23 and the pitching staff holds a collective WHIP of 1.41. Guardians pitchers have relinquished 47 home runs and 190 total runs (18th in the league). Cleveland has allowed 374 base hits (8.9 per 9 innings) and also 175 earned runs. The Guardians have a team ERA of 4.14 so far this season (21st in the league), and the staff has struck out 361 batters. Their pitching staff has walked 162 opposing players and their FIP sits at 4.18 as a team so far this year.
The Guardians relievers have a save percentage of 73.7% and have stepped onto the mound in 57 save situations. The relief pitchers have inherited 52 base runners this year and 32.7% of them earned a run for their team. Guardians pitchers have entered the contest with opponents on base 36 times as well as having 44 appearances in high leverage situations. The Guardians have dispatched 151 relievers to the mound this year. The relief pitchers have notched 38 holds on the year (1st in MLB). They have tallied 14 saves on the year and have blown 5 out of their 19 save opportunities.
The Guardians have turned 67.6% of balls hit into play into outs out of their 3,420 innings on the diamond, ranking them 28th in pro baseball. The Cincinnati Reds have earned 1,140 putouts on the campaign, in addition to 324 assists and 28 errors. Their fielding rate sits at .981 which ranks 26th in pro baseball, and have accumulated 34 double plays.
Ortiz has taken the ball for 281 innings and has accumulated 232 punch outs in his career. His ERA is 4.06 (127 earned runs allowed) and his career WHIP is 1.334. He has surrendered 254 base hits (8.1 hits per 9 innings) and has had 121 walks. Ortiz (14-17 career win-loss record) holds a FIP of 4.00 while he has gone up against 1,213 opposing batters during his time in the major leagues.
The Cincinnati Reds hold a team OBP of .318 in addition to a batting average of .236 on the season. They have been rung up on 398 occasions (4th in MLB) and have recorded 350 hits. Cincinnati has compiled 44 home runs on the year and 194 runs batted in. The Reds have a SLG% of .379 and they are recording 4.57 runs per contest (13th in baseball). They have recorded 73 two-baggers, while getting a free base 161 times as well as recording 201 runs.
The Reds are sitting with a team WHIP of 1.189 with a FIP of 4.09 as a staff so far this year. They come in at 7th in the league as a staff in total hits relinquished with 328. The Cincinnati pitching staff have conceded 183 runs this year and come in with a team ERA of 3.75 (163 earned runs yielded). They currently have a K/BB ratio of 8.60 (374 strikeouts against 137 free passes). They have allowed 52 dingers and they surrender 4.21 runs per 9 innings (13th in MLB).
Cincinnati relief pitchers hold an inherited score rate of 31.4% out of their 51 inherited runners. Their relief pitchers have taken the field 43 times in high leverage situations and also on 33 occasions with runners on base. Sitting with 48 save situations, the Reds have accumulated 29 holds and also 6 blown saves. They are ranked 13th in MLB with a save rate of 64.7%, and they have dispatched 147 relievers onto the diamond this season. Cincinnati has called on relievers to take the mound in 17 save chances and they have earned 11 saves.
In 3,519 innings on the diamond, the Reds have accumulated a defensive efficiency of 72.5% (2nd in MLB). The Cincinnati Reds have gotten 19 double plays and own a fielding percentage of .985 (19th in MLB). The Reds have racked up 327 assists, 23 errors and have a total of 1,173 putouts this year.
Petty (0-2 win-loss record in his career) has earned a 22.94 ERA while giving up 22.9 hits per nine innings. He has a strikeout to walk ratio of 0.88 and he has faced 36 hitters during his MLB career. He has given up 13 earned runs while earning a WHIP of 4.118 and being the owner of a FIP of 22.6. In his career, Petty has surrendered 13 base hits while totaling 7 strikeouts in 5 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Cleveland (-210)
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Additional Resources:
Cincinnati Reds - Twitter
Cleveland Guardians - Twitter