Cleveland Guardians vs Detroit Tigers Prediction, 5/22/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Detroit Tigers

Date: Thursday, May 22, 2025

Location: Comerica Park in Detroit, MI

TV: FanDuel Sports Network Detroit

Odds/Point Spread: Cleveland (+120) Detroit (-144)

The Cleveland Guardians (25-21) are en route to Comerica Park on Thursday where they will play the Detroit Tigers (32-17). The odds on this game have the Guardians at +120 while the Tigers are opening at -144. The total has been set at 8. The starting pitchers are Tanner Bibee and Jack Flaherty.

Cleveland has a slugging rate of .380 and have been called out on strikes 360 times, while being walked on 149 occasions. They have tallied 171 RBI's and 346 base knocks so far this season, while their average at the plate is sitting at .233. The Guardians have recorded 60 doubles as a team and have hit 51 baseballs out of the park. They have racked up 182 runs and have an OBP of .307. As a squad, the Cleveland Guardians are notching 4.0 runs per outing, which has them sitting at 22nd in baseball.

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They have a strikeout to walk ratio of 2.35 and the pitching staff holds a collective WHIP of 1.41. Guardians pitchers have conceded 53 home runs in addition to 202 total runs (16th in MLB). Cleveland has allowed 403 hits (9.0 per 9 innings) and 186 earned runs. The Guardians have a team ERA of 4.14 this year (20th in baseball), and the staff has rung up 392 batters. Their pitching staff has walked 167 players from the other team and their FIP comes in at 4.17 as a team on the year.

Guardians bullpen pitchers have come into the game with runners on 38 times as well as having 44 appearances in high leverage situations. The relief pitchers have racked up 38 holds so far this season (2nd in the league). The Guardians relievers have earned a save percentage of 73.7% and have come into the game in 57 save situations. They have earned 14 saves on the year and have not converted 5 of 19 chances to get a save. The bullpen pitchers have inherited 55 base runners so far this year with 32.7% of those players crossed the plate. The Guardians have sent 158 relief pitchers to the hill for the season.

The Cincinnati Reds have earned a total of 1,212 putouts for the season, as well as 346 assists and 30 errors. Their fielding percentage is currently at .981 which has them sitting 27th in pro baseball, and they have turned 37 double plays. The Guardians have turned 67.2% of baseballs in play into outs out of their 3,636 innings on the diamond, which has them sitting 29th in MLB.

Bibee has taken the mound for 366 innings and is sitting with 363 punch outs so far in his MLB career. Bibee (25-16 record in his career) is the owner of a FIP of 3.32 while facing 1,508 hitters in the major leagues. His earned run average is 3.37 (137 earned runs allowed) and he has a career WHIP of 1.166. He has conceded 321 base hits (7.9 hits per 9 innings) and has had 106 walks.

Detroit has accounted for 62 home runs this season and 250 runs batted in. They have hit 74 two-baggers, while getting a free base 163 times as well as scoring 262 runs. The Detroit Tigers have tallied an OBP of .330 as well as a batting average of .259 this season. The Tigers have a team slugging % of .423 and they tally 5.35 runs per game (4th in the league). They have been called out on strikes on 428 occasions (5th in baseball) and have tallied 433 hits.

The Detroit pitching staff have allowed 181 runs this year and come in with a team ERA of 3.37 (163 earned runs conceded). They have surrendered 53 dingers and they surrender 3.74 runs per 9 innings (8th in baseball). The Tigers are sitting with a team WHIP of 1.184 in addition to having a FIP of 3.86 as a unit this season. They have earned a K/BB ratio of 8.80 (425 strikeouts vs 144 walks). They are currently ranked 9th in the league as a pitching staff in total hits conceded with 371.

Detroit has had bullpen pitchers step onto the mound in 21 save chances and they have come away with 14 saves. They are ranked 9th in baseball holding a save rate of 66.7%, and they have sent 144 bullpen pitchers to the hill on the year. Their relievers have stepped onto the hill 40 times in high leverage situations and on 48 occasions with runners on base. Detroit relievers have an inherited score percentage of 28.8% of 66 inherited runners. With 43 save situations, the Tigers have amassed 20 holds in addition to 7 blown saves.

In their 3,915 innings played, the Tigers hold a defensive efficiency of 71.5% (8th in MLB). The Detroit Tigers have turned 36 double plays and hold a fielding percentage of .988 (9th in professional baseball). The Tigers have recorded 425 assists, 21 errors and have a tally of 1,305 putouts over the course of the season.

Flaherty (57-46 career mark) has a 3.68 earned run average and has given up 7.5 hits per nine innings. He has a strikeout to walk ratio of 3.25 and he has gone up against 3,633 opposing batters so far in his career. He has conceded 358 ER's while earning a WHIP of 1.186 and having a FIP of 3.6. So far in his pro baseball career, Flaherty has allowed 731 hits while earning 998 strikeouts in 875 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Detroit (-144)

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