Cleveland Guardians vs Houston Astros Prediction, 7/8/2025 MLB Picks, Best Bets & Odds
Game: Cleveland Guardians vs Houston Astros
Date: Tuesday, July 8, 2025
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Cleveland (+106) Houston (-128)
The Cleveland Guardians (40-48) are on their way to Daikin Park on Tuesday where they will take on the Houston Astros (55-35). The moneyline on this game has Cleveland at +106 while Houston is sitting at -128. The over/under is set at 8. The starting pitchers are Joey Cantillo and Hunter Brown.


As a team, the Cleveland Guardians are putting up 3.6 runs/g, which is 27th in the league. They have accounted for 312 runs while holding a team OBP of .295. The Guardians have tallied 122 two-baggers as a team and have hit 85 baseballs out of the stadium. They have accrued 297 RBI's as well as 641 hits this season, while their team batting average is .224. Cleveland has a slugging rate of .361 and have been called out on strikes 726 times, while drawing a walk on 272 occasions.
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The Guardians have an earned run average of 3.96 so far this season (18th in the league), and the staff has rung up 737 batters. Guardians pitchers have given up 92 home runs and also 371 total runs (15th in the league). They have walked 325 opposing players and their FIP comes in at 4.11 as a team on the season. Cleveland has conceded 734 hits (8.5 per 9 innings) as well as 342 earned runs. They have earned a strikeout to walk ratio of 2.27 and their pitching staff has earned a collective WHIP of 1.36.
The Guardians relievers have recorded a save percentage of 71.9% and have entered the game in 92 save situations. The bullpen pitchers have inherited 108 runners this year with 37.0% of those runners earned a run for their team. Guardians relief pitchers have entered the game with runners on base 75 times as well as having 86 appearances in high leverage situations. The Guardians have dispatched 294 relief pitchers to the mound so far this year. The relievers have racked up 59 holds on the season (7th in baseball). They have accumulated 23 saves for the season and have blown 9 out of their 32 save opportunities.
The Cincinnati Reds have a total of 2,331 putouts so far this season, in addition to 702 assists and 65 errors. Their fielding percentage is holding at .979 which has them sitting 28th in professional baseball, and they have turned 68 double plays. The Guardians have converted 68.3% of balls in play into outs out of their 6,993 innings on the field, which has them sitting at 25th in professional baseball.
Cantillo has taken the mound for 69 innings and is sitting with 85 strikeouts during his MLB career. Cantillo (3-4 record in his career) is the owner of a FIP of 4.22 while going up against 301 opposing hitters in the majors. His ERA is 4.28 (33 earned runs allowed) and his career WHIP is 1.354. He has allowed 62 base hits (8.0 hits per nine innings) with 32 free passes.
Houston has compiled 102 long balls for the year as well as 377 RBIs. They have hit 133 two-baggers, while getting a free base 261 times as well as notching 396 runs. The Houston Astros have accounted for an OBP of .326 as well as a team batting average of .261 so far this year. The Astros have a team slugging percentage of .412 and they have an average of 4.40 runs per game (16th in MLB). They have been rung up on 692 occasions (26th in MLB) and have tallied 792 hits.
The Houston pitching staff have surrendered 325 runs on the year while holding an ERA of 3.48 (308 earned runs relinquished). They have allowed 96 long balls and they surrender 3.67 runs per 9 innings (2nd in the league). The Astros hold a team WHIP of 1.162 and are the owners of a FIP of 3.58 as a squad on the campaign. They currently have a strikeout to walk ratio of 9.80 (871 strikeouts vs 263 walks). They are sitting at 1st in MLB as a pitching staff in total hits surrendered with 662.
Houston has had relievers step onto the mound in 39 save chances and they have come away with 30 saves. They are ranked 1st in the league with a save percentage of 76.9%, and they have sent 275 relievers to the mound this season. Their relievers have stepped onto the mound 92 times in high leverage situations and on 65 occasions with runners on. Houston bullpen pitchers hold an inherited score rate of 26.3% of 95 inherited base runners. With 100 save situations, the Astros have compiled 60 holds in addition to 9 blown saves.
In 7,170 innings played, the Astros hold a defensive efficiency of 70.8% (10th in the majors). The Houston Astros have gotten 56 double plays and have accounted for a fielding rate of .987 (9th in the majors). The Astros have accrued 697 assists, 40 errors and have accumulated 2,390 putouts on the campaign.
Brown (33-25 career record) has earned a 3.54 ERA and has allowed 7.9 hits per nine innings. He has a strikeout to walk ratio of 3.34 and he has gone up against 1,850 hitters so far in his career. He has conceded a total of 177 earned runs while earning a WHIP of 1.209 and having a FIP of 3.5. During his MLB career, Brown has surrendered 393 base hits while tallying 505 strikeouts in 450 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Houston (-128)
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Additional Resources:
Houston Astros - Twitter
Cleveland Guardians - Twitter