Colorado Rockies vs San Diego Padres Prediction, 9/14/2025 MLB Picks, Best Bets & Odds

Game: Colorado Rockies vs San Diego Padres

Date: Sunday, September 14, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Colorado (+120) San Diego (-144)

Petco Park is the site where the San Diego Padres (80-67) will go up against the Colorado Rockies (40-107) on Sunday. The line on this matchup has the Rockies at +120 and the Padres are priced at -144. The total has been set at 9. The men taking the mound will be German Marquez and Yu Darvish.

Colorado has a slugging rate of .388 and have struck out 1,382 times, while drawing a walk on 366 occasions. They have 531 RBI's and 1,172 hits over the course of the season, while their batting average is at .238. The Rockies have tallied 235 doubles as a squad and have smacked 144 balls out of the stadium. They have tallied 545 runs scored while holding a team on-base percentage of .295. As a unit, the Colorado Rockies are knocking in 3.7 runs per contest, which puts them at 29th in the league.

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The Rockies have a team ERA of 5.98 for the season (30th in baseball), and the staff has rung up 985 batters. Rockies pitchers have yielded 224 long balls in addition to 933 total runs (30th in MLB). They have walked 506 players from the other team and their FIP comes in at 5.20 as a unit this year. Colorado has surrendered 1,540 base knocks (10.8 per 9 innings) and 851 earned runs. They have a K/BB ratio of 1.95 and the pitching staff has a collective WHIP of 1.60.

Rockies relief pitchers have stepped onto the hill with runners on 151 times and also have had 129 appearances in high leverage situations. The relief pitchers have racked up 51 holds on the campaign (30th in baseball). The Rockies relief pitchers have recorded a save rate of 52.0% and have come into the game in 101 save situations. They have accumulated 26 saves so far this year and have missed out on 24 of 50 save opportunities. The relievers have inherited 258 base runners for the season with 36.0% of those runners crossed the plate. The Rockies have dispatched 483 relievers to the mound on the year.

The Rockies have turned 65.7% of baseballs in play into outs in their 11,523 innings on the diamond, which has them ranked 30th in professional baseball. The Cleveland Guardians have a tally of 3,841 putouts this year, as well as 1,353 assists and 103 errors. Their fielding percentage is holding at .981 which ranks 29th in the majors, and have accumulated 142 double plays.

Marquez has taken the mound for 1,132 innings and has 1,063 punch outs during his pro baseball career. His earned run average is 4.61 (580 ER's allowed) and he has a career WHIP of 1.328. He has conceded 1,156 hits (9.2 hits per nine innings) and has 348 free passes. Marquez (68-69 win-loss mark in his career) has earned a FIP of 4.54 while he has gone up against 4,840 hitters in the major leagues.

The San Diego Padres have compiled an OBP of .320 and a batting average of .251 on the campaign. They have been rung up on 1,046 occasions (28th in MLB) and have notched a total of 1,232 base hits. San Diego has recorded 129 home runs over the course of the season to go along with 582 RBIs. The Padres have a team SLG% of .385 and they tally 4.21 runs per outing (24th in baseball). They have tallied 238 doubles, while taking a walk 469 times as well as racking up 619 runs.

The San Diego pitching staff have given up 565 runs on the campaign while having a team ERA of 3.62 (523 earned runs allowed). They have conceded 157 home runs and they yield 3.91 runs per 9 innings (2nd in MLB). The Padres hold a team WHIP of 1.205 with a FIP of 3.99 as a team on the season. Their strikeout to walk ratio comes in at 8.90 (1,278 strikeouts against 481 bases on balls). They rank 1st in baseball as a staff in total hits conceded with 1,084.

Sitting with 160 save situations, the Padres have amassed 94 holds in addition to 16 blown saves. San Diego has had relief pitchers step onto the hill in 61 save opportunities and they have recorded 45 saves. Their relievers have stepped onto the hill 196 times in high leverage situations and on 166 occasions with runners on. San Diego relievers have an inherited score percentage of 28.8% of 236 inherited base runners. They sit at 1st in MLB with a save rate of 73.8%, and they have sent 520 bullpen pitchers to the hill so far this year.

The San Diego Padres have gotten 106 double plays and have a fielding rate of .986 (14th in the majors). The Padres have accrued 1,112 assists, 69 errors and have amassed 3,897 putouts on the season. Out of their 11,691 innings played, the Padres hold a defensive efficiency of 71.8% (2nd in MLB).

Darvish (113-93 career mark) is the owner of a 3.64 ERA and has conceded 7.4 hits per nine innings. He has a strikeout to walk ratio of 3.68 and he has faced 7,246 opposing batters in his career. He has given up a total of 714 earned runs while holding a WHIP of 1.137 and a FIP of 3.6. So far in his pro baseball career, Darvish has allowed 1,444 hits while he has earned 2,062 K's in 1,763 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-144)

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