Detroit Tigers vs Boston Red Sox Prediction, 9/27/2025 MLB Picks, Best Bets & Odds

Game: Detroit Tigers vs Boston Red Sox

Date: Saturday, September 27, 2025

Location: Fenway Park in Boston, MA

TV: NESN

Odds/Point Spread: Detroit (+132) Boston (-160)

The Detroit Tigers (85-73) are hitting the road to Fenway Park on Saturday where they will take on the Boston Red Sox (87-71). The moneyline on this game has Detroit at +132 while Boston is coming in at -160. The betting total is set at 8. The men taking the mound will be Chris Paddack and Kyle Harrison.

Detroit is slugging .415 and have been rung up 1,412 times, while drawing a walk on 495 occasions. They have accounted for 712 RBI's and 1,313 base knocks this year, while their batting average is sitting at .247. The Tigers have accumulated 241 doubles as a team and have hit 194 baseballs out of the park. They have 746 runs and have an on-base percentage of .316. As a team, the Detroit Tigers are notching 4.7 runs per game, which has them at 11th in the league.

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Their strikeout to walk ratio sits at 2.80 and the pitching staff has a collective WHIP of 1.25. Tigers pitchers have conceded 185 long balls and 680 total runs (17th in the league). Detroit has allowed 1,280 base knocks (8.2 per 9 innings) and 619 earned runs. The Tigers have an earned run average of 3.97 over the course of the season (16th in baseball), and the staff has rung up 1,337 hitters. They have walked 477 opposing hitters and their FIP sits at 4.09 as a squad on the season.

Tigers pitchers have come into the game with runners on base 177 times as well as having 133 appearances in high leverage situations. The bullpen have a total of 71 holds so far this season (26th in MLB). The Tigers relievers have accumulated a save percentage of 64.4% and have stepped onto the mound in 134 save situations. They have compiled 38 saves for the season and have blown 21 of their 59 save opportunities. The bullpen pitchers have inherited 251 base runners over the course of the season and 28.7% of those runners crossed the plate. The Tigers have dispatched 495 relievers to the hill this season.

The Colorado Rockies are sitting with 4,206 putouts this year, as well as 1,352 assists and 78 errors. Their fielding percentage is currently at .986 which ranks 14th in MLB, and they have turned 126 double plays. The Tigers have turned 70.2% of balls in play into outs out of 12,618 innings on the diamond, ranking them 13th in the majors.

Paddack has pitched in 576 innings and has earned 524 K's during his career. Paddack (32-35 career record) holds a FIP of 4.55 while he has gone up against 2,417 opposing batters during his time in the major leagues. His ERA is 4.62 (296 earned runs allowed) and he has a WHIP of 1.207. He has allowed 574 base knocks (9.0 hits per nine innings) with 122 free passes.

The Boston Red Sox have an on-base percentage of .325 and a batting average of .255 for the season. They have struck out on 1,381 instances (8th in MLB) and are sitting with 1,386 base hits. Boston has 184 HRs on the campaign as well as 738 runs batted in. The Red Sox hold a team slugging % of .423 and they are scoring 4.91 runs per game (5th in baseball). They have hit 316 doubles, while walking 510 times as well as notching 776 runs.

The Boston pitching staff have yielded 662 runs for the year and come in with a team ERA of 3.72 (584 earned runs conceded). They have allowed 161 dingers and they concede 4.22 runs per 9 innings (11th in MLB). The Red Sox hold a team WHIP of 1.285 in addition to having a FIP of 3.99 as a unit on the campaign. Their K/BB ratio comes in at 8.40 (1,324 strikeouts against 515 free passes). They rank 15th in MLB as a staff in total hits surrendered with 1,301.

Boston has had bullpen pitchers take the mound in 72 save opportunities and they have recorded 44 saves. They rank 21st in the league with a save rate of 61.1%, and they have sent 522 relievers to the mound on the year. Their relievers have taken the field 186 times in high leverage situations and also on 154 occasions with base runners. Boston bullpen pitchers have an inherited score rate of 33.2% out of their 211 inherited base runners. With 158 save situations, the Red Sox have accumulated 84 holds and also 28 blown saves.

Out of their 12,720 innings on the diamond, the Red Sox are sitting with a efficiency on defense of 69.1% (21st in baseball). The Boston Red Sox have turned 126 double plays and have notched a fielding percentage of .980 (30th in MLB). The Red Sox have accrued 1,434 assists, 114 errors and have earned 4,240 putouts for the season.

During his pro baseball career, Harrison has given up 182 hits and he has 185 K's in 191 innings. Harrison (9-9 career win-loss record) has earned a 4.33 ERA while giving up 8.6 hits per 9 innings. He has given up a total of 92 earned runs while holding a WHIP of 1.287 and being the owner of a FIP of 4.3. His K/BB ratio is 2.89 and he has faced 816 hitters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Boston (-160)

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