Detroit Tigers vs Chicago White Sox Prediction, 6/5/2025 MLB Picks, Best Bets & Odds
Game: Detroit Tigers vs Chicago White Sox
Date: Thursday, June 5, 2025
Location: Rate Field in Chicago, IL
TV: Chicago Sports Network
Odds/Point Spread: Detroit (-144) Chicago (+120)
The Detroit Tigers (40-22) are traveling to Rate Field on Thursday where they will compete against the Chicago White Sox (19-42). The odds on this game have the Tigers at -144 and the White Sox are sitting at +120. The betting total is set at 8.5. The starting pitchers will be Casey Mize and Sean Burke.


As a team, the Detroit Tigers are putting up 5.0 runs per outing, which ranks them 5th in baseball. They have notched a total of 310 runs while holding a team on-base percentage of .323. The Tigers have hit 95 two-baggers as a squad and have hit 73 baseballs out of the park. They have compiled 296 RBI's and 526 hits on the year, while their batting average is at .251. Detroit is slugging .410 and have been called out on strikes 557 times, while drawing a walk on 206 occasions.
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The Tigers hold a team earned run average of 3.20 on the year (5th in MLB), and their staff has struck out 530 batters. Tigers pitchers have conceded 58 home runs and 219 runs in total (7th in the league). They have walked 177 opposing players and their FIP sits at 3.63 as a team this year. Detroit has surrendered 464 base hits (7.6 per 9 innings) as well as 196 earned runs. They have accrued a K/BB ratio of 2.99 and the pitching staff has earned a collective WHIP of 1.16.
The Tigers have dispatched 186 relief pitchers to the mound this year. The relievers have inherited 91 runners on the campaign and 27.5% of those runners ended up crossing the plate. They have recorded 19 saves on the season and have missed out on 8 out of their 27 save opportunities. The Tigers bullpen have a save percentage of 70.4% and have come into the game in 65 save situations. The bullpen have notched 35 holds over the course of the season (14th in the league). Tigers pitchers have gone to the mound with runners on 67 times as well as having 54 appearances in high leverage situations.
The Tigers have turned 71.5% of balls hit into play into outs out of their 4,959 innings, ranking them 6th in the majors. The Colorado Rockies have accumulated 1,653 putouts on the year, as well as 534 assists and 25 errors. Their fielding percentage sits at .989 which has them ranked 5th in the majors, and have accumulated 48 double plays.
Mize (15-20 mark in his career) sits with a FIP of 4.07 while he has gone up against 1,450 opposing batters in the major leagues. He has conceded 339 hits (8.9 hits per 9 innings) and has had 97 free passes. His ERA is 4.13 (157 ER's allowed) and his career WHIP is 1.275. Mize has taken the hill for 342 innings and has 271 strikeouts thus far in his career.
Chicago has knocked in 48 home runs this year to go along with 203 RBIs. They have put up 90 doubles, while getting a free base 198 times as well as putting up 210 runs. The Chicago White Sox have compiled a team on-base percentage of .294 and a batting average of .221 this year. The White Sox have a team slugging percentage of .342 and they are scoring 3.44 runs per contest (26th in the league). They have been called out on strikes on 513 occasions (11th in baseball) and are sitting with 440 base knocks.
The White Sox have a WHIP of 1.376 with a FIP of 4.54 as a pitching staff for the season. Their K/BB ratio is 7.60 (442 strikeouts against 226 walks). They come in at 15th in MLB as a pitching staff in total hits relinquished with 494. They have allowed 66 long balls and they surrender 4.59 runs per 9 innings (23rd in MLB). The Chicago pitching staff have conceded 267 runs on the season while having a team ERA of 4.20 (244 earned runs relinquished).
Sitting with 45 save situations, the White Sox have earned 29 holds in addition to 11 blown saves. Chicago has had relievers enter the game in 16 save opportunities and they have converted 5 saves. Their relief pitchers have taken the field 52 times in high leverage situations and also on 60 occasions with base runners. Chicago relief pitchers hold an inherited score percentage of 30.2% out of their 86 inherited base runners. They are ranked 30th in the league with a save percentage of 31.3%, and they have dispatched 194 bullpen pitchers to the hill this year.
The Chicago White Sox have turned 45 double plays and have earned a fielding percentage of .981 (28th in professional baseball). The White Sox have recorded 490 assists, 40 errors and have earned 1,571 putouts this year. In their 4,713 innings on the field, the White Sox are sitting with a defensive efficiency of 70.0% (17th in the majors).
During his career, Burke has conceded 66 base hits while he has earned 67 punch outs in 79 innings pitched. He has conceded 31 ER's while earning a WHIP of 1.316 and having a FIP of 3.5. He has a K/BB ratio of 1.76 and he has faced 340 opposing batters thus far in his career. Burke (5-6 record in his career) has earned a 3.53 ERA and has conceded 7.5 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Detroit (-144)
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Additional Resources:
Chicago White Sox - Twitter
Detroit Tigers - Twitter