Detroit Tigers vs Cleveland Guardians Prediction, 7/4/2025 MLB Picks, Best Bets & Odds
Game: Detroit Tigers vs Cleveland Guardians
Date: Friday, July 4, 2025
Location: Progressive Field in Cleveland, OH
TV: CLEGuardians.TV
Odds/Point Spread: Detroit (-150) Cleveland (+125)
The Cleveland Guardians (40-43) will play the Detroit Tigers (53-32) at Progressive Field on Friday. The moneyline on this contest has Detroit at -150 and Cleveland is at +125. The total has been set at 9. The pitchers taking the mound are Casey Mize and Slade Cecconi.


The Tigers have accumulated 137 doubles as a team and have knocked 106 baseballs out of the stadium. Detroit has a slugging rate of .427 and have struck out 736 times, while drawing a walk on 270 occasions. As a team, the Detroit Tigers are recording 5.0 runs/g, which is 5th in MLB. They have amassed 406 runs batted in in addition to 734 hits on the season, and their average at the plate is at .255. They have tallied 424 runs while holding a team on-base percentage of .325.
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The Tigers hold a team earned run average of 3.44 this year (3rd in MLB), and their staff has struck out 720 hitters. Tigers pitchers have given up 89 long balls and 325 runs (4th in the league). Their pitching staff has walked 242 opposing batters and their FIP sits at 3.81 as a unit on the campaign. Detroit has given up 654 hits (7.8 per 9 innings) and 289 earned runs. They have accrued a K/BB ratio of 2.98 and their pitching staff has recorded a WHIP of 1.19.
The Tigers have sent 262 relievers to the mound on the campaign. The bullpen pitchers have inherited 127 base runners over the course of the season and 25.2% of those players crossed home plate. They have accumulated 24 saves for the season and have not converted 10 of 34 save opportunities. The Tigers bullpen have accumulated a save percentage of 70.6% and have entered the game in 82 save situations. The relief pitchers have accumulated 45 holds this season (21st in baseball). Tigers bullpen pitchers have entered the contest with runners on 94 times and also have had 72 appearances in high leverage situations.
The Colorado Rockies are sitting with 2,269 putouts this year, in addition to 733 assists and 38 errors. Their fielding percentage is currently at .988 which has them ranked 9th in professional baseball, and have a total of 71 double plays. The Tigers have turned 71.2% of baseballs in play into outs out of their 6,807 innings on the field, ranking them 6th in the majors.
Mize (17-21 career mark) has earned a FIP of 3.99 and he has faced 1,569 batters during his time in the majors. He has conceded 369 hits (9.0 hits per 9 innings) and has had 104 walks. His earned run average is 4.05 (166 ER's allowed) and his WHIP is 1.281. Mize has taken the mound for 369 frames and has accumulated 295 K's in his MLB career.
The Guardians have a team SLG% of .364 and they score 3.67 runs per outing (26th in the league). They have recorded 115 two-baggers, while taking a walk 259 times and putting up 305 runs. Cleveland has tallied 81 home runs over the course of the season as well as 290 runs batted in. They have been called out on strikes on 687 occasions (18th in the league) and have 608 base hits. The Cleveland Guardians have accounted for a team on-base percentage of .297 as well as a team batting average of .225 for the year.
The Guardians have a WHIP of 1.380 in addition to having a FIP of 4.10 as a squad this season. They have earned a K/BB ratio of 8.50 (691 strikeouts against 302 free passes). They rank 16th in the league as a staff in total hits surrendered with 707. They have surrendered 87 homers and they concede 4.37 runs per 9 innings (17th in MLB). The Cleveland pitching staff have allowed 355 runs on the year while holding a team ERA of 4.05 (329 earned runs surrendered).
Cleveland has called on relievers to enter the contest in 31 save opportunities and they have converted 23 saves. They sit at 3rd in baseball holding a save rate of 74.2%, and they have dispatched 277 relievers to the mound on the campaign. Their relief pitchers have taken the field 80 times in high leverage situations and also on 71 occasions with runners on. Cleveland relief pitchers hold an inherited score percentage of 39.2% out of 102 inherited base runners. Sitting with 91 save situations, the Guardians have compiled 59 holds in addition to 8 blown saves.
The Cleveland Guardians have turned 66 double plays and hold a fielding percentage of .978 (28th in MLB). The Guardians have 668 assists, 63 errors and have earned 2,194 putouts on the season. Out of their 6,582 innings on the diamond, the Guardians have a defensive efficiency of 67.7% (28th in pro baseball).
In his pro baseball career, Cecconi has given up 160 base hits while he has earned 126 strikeouts in 146 frames. He has given up 87 ER's while holding a WHIP of 1.336 and being the owner of a FIP of 5.3. His K/BB ratio is 3.60 and he has faced 628 opposing batters during his pro baseball career. Cecconi (5-11 mark in his career) holds a 5.36 earned run average while allowing 9.9 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Detroit (-150)
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Additional Resources:
Cleveland Guardians - Twitter
Detroit Tigers - Twitter