Detroit Tigers vs Pittsburgh Pirates Prediction, 7/21/2025 MLB Picks, Best Bets & Odds

Game: Detroit Tigers vs Pittsburgh Pirates

Date: Monday, July 21, 2025

Location: PNC Park in Pittsburgh, PA

TV: SportsNet Pittsburgh

Odds/Point Spread: Detroit (-145) Pittsburgh (+125)

The Pittsburgh Pirates (39-58) will try to defeat the Detroit Tigers (59-38) at PNC Park on Monday. The moneyline on this game has Detroit at -145 while Pittsburgh is priced at +125. The over/under is set at 8. The pitchers taking the mound will be Casey Mize and Mitch Keller.

The Tigers have tallied 153 two-baggers as a squad and have smacked 124 balls out of the park. Detroit is slugging .425 and have been called out on strikes 848 times, while taking a walk on 317 occasions. As a unit, the Detroit Tigers are earning 5.0 runs/g, which ranks them 6th in the league. They have 463 RBI's and 825 base knocks this season, while their team batting average comes in at .252. They are sitting with 482 runs scored while holding a team OBP of .324.

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The Tigers hold a team ERA of 3.69 on the year (9th in MLB), and the staff has struck out 820 batters. Tigers pitchers have relinquished 105 home runs and also 395 runs in total (14th in the league). Their pitching staff has walked 283 opposing hitters and their FIP is 3.88 as a squad on the season. Detroit has yielded 777 base knocks (8.1 per 9 innings) and 354 earned runs. They have earned a strikeout to walk ratio of 2.90 and their pitching staff holds a collective WHIP of 1.23.

Tigers bullpen pitchers have stepped onto the hill with opponents on base 110 times and also have had 83 appearances in high leverage situations. The relievers have a total of 50 holds so far this season (21st in MLB). The Tigers bullpen have a save rate of 67.5% and have come into the game in 93 save situations. They have 27 saves this season and have blown 13 out of their 40 chances to save the game. The relief pitchers have inherited 149 runners for the year with 26.8% of them earned a run for their team. The Tigers have sent 303 relievers to the mound this year.

The Colorado Rockies have amassed 2,590 putouts this season, as well as 834 assists and 46 errors. Their fielding percentage is holding at .987 which has them ranked 14th in pro baseball, and they have turned 80 double plays. The Tigers have converted 70.3% of balls hit into play into outs out of 7,770 innings on the field, ranking them 13th in the majors.

Mize (18-22 career record) is the owner of a FIP of 4.02 while he has gone up against 1,611 hitters in the major leagues. He has surrendered 379 base hits (9.0 hits per nine innings) and has 107 free passes. His earned run average is 4.08 (172 earned runs allowed) and his career WHIP is 1.282. Mize has taken the hill for 379 innings and has tallied 303 K's in his pro baseball career.

The Pirates hold a team slugging percentage of .339 and they have an average of 3.36 runs per outing (30th in the league). They have recorded 126 two-baggers, while getting a free base 303 times as well as earning 326 runs. Pittsburgh has hit 66 home runs for the year as well as 315 runs batted in. They have struck out on 845 occasions (6th in MLB) and have 736 base hits. The Pittsburgh Pirates have accumulated a team on-base percentage of .300 in addition to a batting average of .230 so far this season.

The Pirates have a WHIP of 1.203 with a FIP of 3.90 as a pitching staff for the year. Their strikeout to walk ratio sits at 7.60 (720 strikeouts against 278 bases on balls). They are currently ranked 7th in baseball as a staff in total hits surrendered with 748. They have yielded 92 homers and they allow 4.00 runs per 9 innings (8th in MLB). The Pittsburgh pitching staff have yielded 379 runs this year while having an ERA of 3.73 (354 earned runs relinquished).

With 79 save situations, the Pirates have amassed 43 holds in addition to 15 blown saves. Pittsburgh has called on relievers to step onto the hill in 34 save chances and they have walked away with 19 saves. Their relievers have come in 98 times in high leverage situations and on 89 occasions with runners on base. Pittsburgh relievers have an inherited score percentage of 32.9% of 140 inherited runners. They are ranked 26th in the league holding a save rate of 55.9%, and they have sent 296 bullpen pitchers onto the diamond this year.

In their 7,683 innings played, the Pirates are sitting with a defensive efficiency of 71.7% (2nd in pro baseball). The Pittsburgh Pirates have turned 77 double plays and own a fielding percentage of .987 (10th in MLB). The Pirates have recorded 832 assists, 44 errors and have accounted for 2,561 putouts this year.

In his pro baseball career, Keller has allowed 852 base hits while he has earned 779 punch outs in 820 frames. He has given up a total of 404 earned runs while holding a WHIP of 1.374 and being the owner of a FIP of 4.4. He has a K/BB ratio of 2.83 and he has faced 3,562 hitters during his MLB career. Keller (39-60 record in his career) holds a 4.43 earned run average and has given up 9.3 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Pittsburgh (+125)

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