Detroit Tigers vs Pittsburgh Pirates Prediction, 7/22/2025 MLB Picks, Best Bets & Odds

Game: Detroit Tigers vs Pittsburgh Pirates

Date: Tuesday, July 22, 2025

Location: PNC Park in Pittsburgh, PA

TV: SportsNet Pittsburgh

Odds/Point Spread: Detroit (-150) Pittsburgh (+125)

PNC Park is the location where the Pittsburgh Pirates (39-61) will go up against the Detroit Tigers (60-40) on Tuesday. The moneyline on this contest has Detroit at -150 while Pittsburgh is coming in at +125. The over/under is set at 9. The pitchers who are expected to start are Casey Mize and Mitch Keller.

Detroit is slugging .419 and have struck out 871 times, while being walked on 329 occasions. They have accounted for 466 RBI's in addition to 841 hits this year, while their team batting average sits at .250. The Tigers have recorded 154 two-baggers as a team and have smacked 125 balls out of the park. They are sitting with 485 runs and have an OBP of .322. As a unit, the Detroit Tigers are earning 4.9 runs per game, which has them sitting at 6th in the league.

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The Tigers hold a team ERA of 3.66 on the year (7th in baseball), and they have struck out 853 hitters. Tigers pitchers have conceded 106 long balls and also 402 runs in total (11th in the league). They have walked 289 opposing hitters and their FIP comes in at 3.83 as a team this year. Detroit has given up 789 hits (8.0 per 9 innings) as well as 361 earned runs. They have a K/BB ratio of 2.95 and the pitching staff has a team WHIP of 1.21.

The Tigers have sent 311 relief pitchers to the hill on the campaign. The bullpen pitchers have inherited 154 base runners this season with 26.6% of them ended up crossing the plate. They have accumulated 28 saves over the course of the season and have blown 14 of their 42 save chances. The Tigers bullpen have a save rate of 66.7% and have entered the game in 95 save situations. The bullpen have recorded 50 holds on the season (22nd in MLB). Tigers bullpen pitchers have entered the game with opponents on base 113 times as well as having 86 appearances in high leverage situations.

The Colorado Rockies have earned a total of 2,590 putouts this year, in addition to 834 assists and 46 errors. Their fielding rate sits at .987 which puts them in 14th in the majors, and they have turned 80 double plays. The Tigers have transformed 70.3% of balls hit into play into outs in their 7,770 innings, which has them sitting at 13th in baseball.

Mize has taken the ball for 379 innings and has 303 K's during his pro baseball career. Mize (18-22 career win-loss record) sits with a FIP of 4.02 while he has faced 1,611 opposing batters during his time in the major leagues. His ERA is 4.08 (172 ER's allowed) and his WHIP is 1.282. He has conceded 379 base hits (9.0 hits per nine innings) and has had 107 free passes.

Pittsburgh has hit 66 home runs for the year as well as 322 RBIs. They have tallied 133 doubles, while getting a free base 310 times as well as putting up 333 runs. The Pittsburgh Pirates hold an on-base percentage of .300 as well as a batting average of .229 this year. The Pirates hold a slugging percentage of .339 and they have an average of 3.33 runs per contest (30th in MLB). They have struck out on 869 occasions (6th in the league) and have recorded 758 hits.

The Pirates have a WHIP of 1.219 and are the owners of a FIP of 3.94 as a squad on the season. They come in at 8th in the league as a pitching staff in total hits given up with 782. The Pittsburgh pitching staff have surrendered 406 runs on the year and come in with a team ERA of 3.90 (381 earned runs conceded). They have earned a K/BB ratio of 7.60 (743 strikeouts vs 291 walks). They have yielded 96 homers and they relinquish 4.15 runs per 9 innings (12th in baseball).

Sitting with 80 save situations, the Pirates have recorded 43 holds in addition to 16 blown saves. Pittsburgh has had bullpen pitchers enter the contest in 35 save chances and they have earned 19 saves. Their relievers have stepped onto the mound 99 times in high leverage situations and also on 94 occasions with base runners. Pittsburgh bullpen pitchers hold an inherited score percentage of 34.0% out of 150 inherited base runners. They are currently ranked 26th in MLB with a save percentage of 54.3%, and they have dispatched 306 relievers to the hill over the course of the season.

In 7,683 innings played, the Pirates are sitting with a efficiency on defense of 71.7% (2nd in MLB). The Pittsburgh Pirates have gotten 77 double plays and hold a fielding percentage of .987 (10th in pro baseball). The Pirates have accrued 832 assists, 44 errors and have accumulated 2,561 putouts for the year.

In his career, Keller has conceded 852 base hits while accumulating 779 punch outs in 820 innings pitched. He has allowed a total of 404 earned runs while earning a WHIP of 1.374 and a FIP of 4.4. He has a K/BB ratio of 2.83 and he has gone up against 3,562 hitters so far in his MLB career. Keller (39-60 win-loss record in his career) has earned a 4.43 earned run average while surrendering 9.3 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Pittsburgh (+125)

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