Houston Astros vs Chicago White Sox Prediction, 5/3/2025 MLB Picks, Best Bets & Odds
Game: Houston Astros vs Chicago White Sox
Date: Saturday, May 3, 2025
Location: Rate Field in Chicago, IL
TV: Chicago Sports Network
Odds/Point Spread: Houston (-132) Chicago (+110)
The Houston Astros (16-14) are hitting the road to Rate Field on Saturday where they will attempt to defeat the Chicago White Sox (7-23). The moneyline on this contest has Houston at -132 and Chicago is coming in at +110. The betting total comes in at 8. The expected starting pitchers are Hunter Brown and Davis Martin.


The Astros have accrued 38 doubles as a team and have knocked 25 baseballs out of the park. Houston is slugging .357 and have been called out on strikes 244 times, while drawing a walk on 98 occasions. As a squad, the Houston Astros are scoring 3.9 runs per outing, which puts them at 21st in the league. They have compiled 110 runs batted in and 233 base knocks so far this season, while their batting average is .236. They have 117 runs while holding a team OBP of .310.
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They have accumulated a K/BB ratio of 3.35 and the pitching staff has a team WHIP of 1.09. Astros pitchers have allowed 29 home runs in addition to 104 runs in total (3rd in MLB). Houston has surrendered 208 hits (7.0 per 9 innings) and 96 earned runs. The Astros have an earned run average of 3.23 on the campaign (5th in the league), and they have rung up 275 batters. They have walked 82 opposing batters and their FIP is 3.45 as a squad for the year.
Astros relief pitchers have stepped onto the hill with opponents on base 22 times as well as having 26 appearances in high leverage situations. The relief pitchers have recorded 22 holds over the course of the season (7th in the league). The Astros relievers have a save rate of 75.0% and stepped onto the hill in 34 save situations. They have recorded 9 saves this season and have blown 3 of 12 save opportunities. The relief pitchers have inherited 30 base runners this season and 30.0% of those runners crossed the plate. The Astros have sent 96 relief pitchers to the hill on the campaign.
The Astros have turned 73.0% of baseballs in play into outs out of their 2,409 innings on the diamond, which has them sitting at 3rd in professional baseball. The Detroit Tigers have 803 putouts on the campaign, as well as 230 assists and 12 errors. Their fielding rate is at .989 which has them sitting 6th in professional baseball, and have a total of 17 double plays.
Brown (28-23 career win-loss record) is the owner of a FIP of 3.73 while he has faced 1,591 opposing hitters in the major leagues. He has surrendered 352 hits (8.3 hits per 9 innings) and has 129 walks. His earned run average is 3.78 (161 ER's allowed) and his WHIP is 1.256. Brown has taken the mound for 383 innings and has 419 strikeouts in his career.
The Chicago White Sox have compiled an on-base percentage of .289 in addition to a batting average of .211 on the campaign. They have been rung up on 255 instances (13th in MLB) and have accounted for 206 base knocks. Chicago has knocked in 24 home runs so far this year as well as 98 runs batted in. The White Sox have a slugging percentage of .325 and they have an average of 3.37 runs per contest (27th in MLB). They have hit 37 two-baggers, while walking 102 times and racking up 101 runs.
The Chicago pitching staff have conceded 133 runs this year and come in with a team ERA of 4.19 (120 earned runs given up). They have surrendered 35 homers and they surrender 4.64 runs per 9 innings (21st in the league). The White Sox hold a team WHIP of 1.380 in addition to having a FIP of 4.76 as a team so far this season. They have earned a strikeout to walk ratio of 8.00 (229 strikeouts vs 123 bases on balls). They sit at 10th in MLB as a pitching staff in total hits allowed with 233.
Chicago has called on bullpen pitchers to enter the game in 4 save chances and they have converted 1 save. They are ranked 30th in baseball with a save percentage of 25.0%, and they have sent 100 relief pitchers onto the diamond on the campaign. Their bullpen pitchers have stepped onto the mound 25 times in high leverage situations and also on 28 occasions with runners on. Chicago relief pitchers have an inherited score rate of 35.0% out of their 40 inherited base runners. Sitting with 13 save situations, the White Sox have 9 holds in addition to 3 blown saves.
The Chicago White Sox have gotten 27 double plays and hold a fielding percentage of .978 (27th in pro baseball). The White Sox have recorded 247 assists, 23 errors and have accounted for 774 putouts over the course of the season. In their 2,322 innings on the field, the White Sox are sitting with a defensive efficiency of 70.4% (13th in baseball).
During his MLB career, Martin has allowed 146 base hits while accumulating 116 K's in 146 innings pitched. He has allowed 70 ER's while earning a WHIP of 1.361 and a FIP of 4.2. His K/BB ratio is 2.19 and he has faced 630 hitters during his pro baseball career. Martin (4-14 record in his career) has earned a 4.31 ERA while giving up 9.0 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Chicago (+110)
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Additional Resources:
Chicago White Sox - Twitter
Houston Astros - Twitter