Houston Astros vs Milwaukee Brewers Prediction, 5/6/2025 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Milwaukee Brewers

Date: Tuesday, May 6, 2025

Location: American Family Field in Milwaukee, WI

TV: FanDuel Sports Network Wisconsin

Odds/Point Spread: Houston (-128) Milwaukee (+106)

American Family Field is where the Milwaukee Brewers (17-18) will compete against the Houston Astros (17-16) on Tuesday. The line on this matchup has the Astros at -128 and the Brewers are opening at +106. The over/under is 8.5. The expected starting pitchers will be Hayden Wesneski and Chad Patrick.

As a squad, the Houston Astros are compiling 4.0 runs per outing, which puts them at 19th in the league. They have 132 runs scored and hold an OBP of .314. The Astros have compiled 43 two-baggers as a squad and have hit 29 baseballs out of the park. They have accumulated 125 runs batted in and 265 base knocks this season, and their team batting average comes in at .243. Houston has a slugging % of .370 and have been called out on strikes 263 times, while drawing a walk on 104 occasions.

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The Astros have a team ERA of 3.34 for the year (5th in MLB), and their staff has rung up 303 batters. Astros pitchers have surrendered 30 home runs in addition to 119 runs (4th in baseball). Their pitching staff has walked 97 players from the other team and their FIP sits at 3.43 as a squad on the season. Houston has conceded 230 base knocks (7.1 per 9 innings) and 108 earned runs. Their K/BB ratio is 3.12 and their pitching staff has earned a collective WHIP of 1.13.

The Astros relief pitchers have a save percentage of 69.2% and have come into the game in 36 save situations. The bullpen pitchers have inherited 37 base runners this year and 29.7% of them crossed the plate. Astros pitchers have entered the game with opponents on base 26 times in addition to having 28 appearances in high leverage situations. The Astros have dispatched 106 relievers to the hill on the year. The bullpen are sitting with 23 holds on the season (11th in the league). They have recorded 9 saves so far this year and have blown 4 of their 13 chances to get a save.

The Astros have converted 72.2% of balls hit into play into outs in their 2,616 innings, which has them ranked 6th in pro baseball. The Detroit Tigers have a total of 872 putouts at this point in the season, in addition to 251 assists and 14 errors. Their fielding rate is holding steady at .988 which puts them in 10th in pro baseball, and have 18 double plays.

Wesneski (10-15 career mark) has a FIP of 3.86 while facing 906 hitters during his time in the major leagues. He has allowed 186 base hits (7.7 hits per 9 innings) and has 64 free passes. His ERA is 3.92 (95 ER's allowed) and his career WHIP is 1.147. Wesneski has thrown 218 frames and has accounted for 209 punch outs during his MLB career.

The Milwaukee Brewers have an OBP of .316 as well as a team batting average of .238 for the season. They have been rung up on 276 instances (19th in baseball) and have tallied 277 hits. Milwaukee has 28 home runs for the season to go along with 146 RBIs. The Brewers hold a slugging percentage of .356 and they average 4.71 runs per contest (10th in baseball). They have recorded 45 two-baggers, while walking 121 times as well as scoring 165 runs.

The Milwaukee pitching staff have given up 159 runs on the year while having an ERA of 4.32 (147 earned runs yielded). They have yielded 43 home runs and they yield 4.68 runs per 9 innings (22nd in baseball). The Brewers are sitting with a team WHIP of 1.343 and are the owners of a FIP of 4.50 as a team this year. They currently have a K/BB ratio of 8.30 (281 strikeouts vs 135 free passes). They rank 16th in MLB as a staff in total hits surrendered with 276.

Milwaukee relievers have an inherited score rate of 47.9% of 48 inherited runners. Their relief pitchers have taken the field 30 times in high leverage situations and on 30 occasions with base runners. Sitting with 29 save situations, the Brewers have compiled 19 holds and 4 blown saves. They rank 23rd in baseball with a save rate of 55.6%, and they have dispatched 125 relief pitchers to the mound this year. Milwaukee has had bullpen pitchers enter the contest in 9 save chances and they have earned 5 saves.

In 2,754 innings on the field, the Brewers are sitting with a efficiency on defense of 70.7% (10th in professional baseball). The Milwaukee Brewers have turned 26 double plays and hold a fielding percentage of .982 (24th in professional baseball). The Brewers have accrued 259 assists, 22 errors and have a tally of 918 putouts this year.

So far in his pro baseball career, Patrick has given up 29 base knocks while accumulating 26 K's in 31 frames. He has conceded a total of 10 earned runs while earning a WHIP of 1.286 and a FIP of 2.9. His K/BB ratio is 2.36 and he has faced 128 hitters during his career. Patrick (1-3 record in his career) has a 2.89 ERA and has given up 8.4 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Milwaukee (+106) and under 8.5 runs

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