Houston Astros vs Sacramento Athletics Prediction, 9/24/2025 MLB Picks, Best Bets & Odds
Game: Houston Astros vs Sacramento Athletics
Date: Wednesday, September 24, 2025
Location: Sutter Health Park in Sacramento, CA
TV: NBC Sports California
Odds/Point Spread: Houston (-122) Sacramento (+102)
The Sacramento Athletics (73-83) are welcoming the Houston Astros (84-72) at Sutter Health Park on Wednesday. The moneyline on this matchup has Houston at -122 and Sacramento is sitting at +102. The over/under is 8. The pitchers taking the mound will be Hunter Brown and J.T. Ginn.


The Astros have accounted for 237 two-baggers as a team and have hit 172 baseballs out of the stadium. Houston has a slugging rate of .398 and have struck out 1,248 times, while drawing a walk on 454 occasions. As a unit, the Houston Astros are scoring 4.2 runs per game, which ranks them 23rd in baseball. They have earned 629 runs batted in as well as 1,328 base knocks so far this year, while their team batting average comes in at .251. They have notched a total of 659 runs while holding a team on-base percentage of .316.
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They have accrued a K/BB ratio of 2.97 and their pitching staff has a collective WHIP of 1.22. Astros pitchers have yielded 192 long balls and also 642 runs (9th in MLB). Houston has conceded 1,211 hits (7.8 per 9 innings) as well as 598 earned runs. The Astros hold a team ERA of 3.87 over the course of the season (11th in baseball), and the staff has rung up 1,454 batters. Their pitching staff has walked 489 players from the other team and their FIP sits at 4.03 as a team on the year.
The Astros have sent 500 relievers to the hill on the season. The relievers have inherited 176 base runners this season and 22.7% of them earned a run for their team. They have earned 45 saves this year and have blown 16 of 61 chances to save the game. The Astros relievers have compiled a save rate of 73.8% and stepped onto the hill in 152 save situations. The relievers have notched 88 holds so far this year (15th in the league). Astros pitchers have entered the contest with runners on 126 times and also have had 166 appearances in high leverage situations.
The Astros have transformed 70.8% of baseballs in play into outs out of their 12,519 innings on the diamond, which has them sitting at 7th in the majors. The Detroit Tigers have earned 4,173 putouts this season, as well as 1,234 assists and 66 errors. Their fielding percentage is currently at .988 which has them sitting 7th in professional baseball, and have 102 double plays.
Brown (36-30 career record) sits with a FIP of 3.40 while he has faced 2,163 hitters in the major leagues. He has conceded 455 base knocks (7.8 hits per nine innings) and has 177 free passes. His earned run average is 3.46 (202 ER's allowed) and his WHIP is 1.201. Brown has taken the ball for 526 frames and has accumulated 580 strikeouts so far in his career.
Sacramento has accounted for 214 HRs this year to go along with 686 runs batted in. They have put up 281 doubles, while taking a walk 483 times and putting up 709 runs. The Sacramento Athletics have accumulated an OBP of .318 and a batting average of .253 this season. The Athletics hold a team SLG% of .432 and they tally 4.54 runs per outing (12th in MLB). They have been rung up on 1,350 instances (10th in MLB) and are sitting with 1,353 base hits.
The Athletics have a WHIP of 1.365 and are the owners of a FIP of 4.70 as a staff this season. They are sitting at 23rd in baseball as a pitching staff in total hits relinquished with 1,340. The Sacramento pitching staff have surrendered 789 runs on the season while having an ERA of 4.72 (725 earned runs surrendered). They currently have a K/BB ratio of 8.30 (1,276 strikeouts against 548 free passes). They have surrendered 217 long balls and they relinquish 5.13 runs per 9 innings (27th in the league).
Sacramento has had relievers enter the game in 55 save chances and they have earned 35 saves. They sit at 15th in MLB with a save percentage of 63.6%, and they have sent 491 relievers onto the field on the year. Their bullpen pitchers have stepped onto the hill 139 times in high leverage situations and on 155 occasions with runners on. Sacramento bullpen pitchers hold an inherited score rate of 27.3% of 227 inherited base runners. With 120 save situations, the Athletics have earned 65 holds and also 20 blown saves.
The Sacramento Athletics have turned 106 double plays and have notched a fielding percentage of .984 (21st in baseball). The Athletics have 1,168 assists, 84 errors and have earned 4,151 putouts for the year. In their 12,453 innings played, the Athletics have a defensive efficiency of 69.7% (18th in the majors).
Ginn (5-7 career win-loss record) has earned a 4.49 earned run average while giving up 9.1 hits per nine innings. He has a K/BB ratio of 3.35 and he has gone up against 513 hitters in his MLB career. He has given up a total of 60 ER's while earning a WHIP of 1.323 and being the owner of a FIP of 4.4. So far in his pro baseball career, Ginn has surrendered 122 base hits while he has earned 124 punch outs in 120 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Sacramento (+102)
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