Los Angeles Angels vs Colorado Rockies Prediction, 9/20/2025 MLB Picks, Best Bets & Odds
Game: Los Angeles Angels vs Colorado Rockies
Date: Saturday, September 20, 2025
Location: Coors Field in Denver, CO
TV: Rockies.TV
Odds/Point Spread: Los Angeles (-150) Colorado (+125)
Coors Field is where the Colorado Rockies (41-111) will take on the Los Angeles Angels (69-83) on Saturday. The odds on this game have the Angels at -150 and the Rockies are at +125. The total is 9. The expected starting pitchers are Kyle Hendricks and German Marquez.


Los Angeles has a slugging % of .398 and have struck out 1,524 times, while drawing a walk on 461 occasions. They have 621 RBI's and 1,144 hits for the year, and their batting average comes in at .226. The Angels have hit 202 doubles as a unit and have hit 211 baseballs out of the park. They have earned 643 runs scored while having a team OBP of .300. As a squad, the Los Angeles Angels are putting up 4.2 runs per game, which ranks them 24th in the league.
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The Angels have an ERA of 4.89 on the year (28th in baseball), and the staff has struck out 1,201 hitters. Angels pitchers have surrendered 211 home runs in addition to 788 runs in total (28th in the league). Their pitching staff has walked 590 opposing players and their FIP is 4.82 as a team for the season. Los Angeles has yielded 1,349 base hits (9.0 per 9 innings) and 730 earned runs. Their strikeout to walk ratio is 2.04 and the pitching staff has earned a collective WHIP of 1.44.
Angels bullpen pitchers have gone to the mound with runners on base 137 times and also have had 199 appearances in high leverage situations. The relievers have earned 78 holds this season (21st in baseball). The Angels relievers have accumulated a save percentage of 51.5% and have stepped onto the mound in 149 save situations. They have earned 35 saves this year and have blown 33 of their 68 save opportunities. The relievers have inherited 207 runners so far this season and 37.7% of those players crossed the plate. The Angels have dispatched 525 relievers to the mound for the season.
The Kansas City Royals have earned a total of 4,033 putouts this season, in addition to 1,321 assists and 91 errors. Their fielding percentage is holding at .983 which has them sitting 26th in professional baseball, and have a total of 152 double plays. The Angels have transformed 68.8% of balls hit into play into outs in their 12,099 innings, ranking them 25th in the majors.
Hendricks (104-91 career mark) is the owner of a FIP of 3.75 while going up against 7,167 batters during his time in the major leagues. He has conceded 1,660 hits (8.6 hits per 9 innings) and has 407 free passes. His ERA is 3.80 (732 earned runs allowed) and he has a WHIP of 1.193. Hendricks has taken the mound for 1,732 innings and has totaled 1,360 strikeouts during his pro baseball career.
The Colorado Rockies have an on-base percentage of .295 as well as a batting average of .239 on the campaign. They have been rung up on 1,430 occasions (2nd in the league) and have totaled 1,216 hits. Colorado has accumulated 150 home runs for the year as well as 552 runs batted in. The Rockies have a slugging percentage of .388 and they earn 3.73 runs per contest (29th in the league). They have 240 doubles, while walking 374 times and scoring 567 runs.
The Rockies hold a team WHIP of 1.599 in addition to having a FIP of 5.22 as a pitching staff on the season. They are currently ranked 30th in the league as a staff in total hits surrendered with 1,592. The Colorado pitching staff have allowed 969 runs for the season while having an ERA of 6.03 (886 earned runs conceded). Their K/BB ratio is 6.90 (1,010 strikeouts vs 524 bases on balls). They have allowed 231 homers and they give up 6.59 runs per 9 innings (30th in the league).
Colorado has called on relief pitchers to take the mound in 51 save chances and they have come away with 27 saves. They sit at 27th in the league holding a save percentage of 52.9%, and they have sent 501 relievers to the mound on the year. Their relief pitchers have stepped onto the mound 131 times in high leverage situations and on 156 occasions with runners on base. Colorado relievers hold an inherited score rate of 34.8% of 267 inherited runners. Sitting with 104 save situations, the Rockies have recorded 53 holds in addition to 24 blown saves.
The Colorado Rockies have turned 146 double plays and have accounted for a fielding rate of .981 (29th in the majors). The Rockies have racked up 1,391 assists, 106 errors and have a tally of 3,970 putouts so far this year. Out of their 11,910 innings played, the Rockies have earned a efficiency on defense of 65.8% (30th in baseball).
Marquez (68-70 career win-loss mark) has a 4.65 ERA while allowing 9.2 hits per nine innings. His strikeout to walk ratio is 3.04 and he has gone up against 4,859 batters in his career. He has allowed 586 earned runs while holding a WHIP of 1.335 and having a FIP of 4.6. During his MLB career, Marquez has allowed 1,165 hits and he has 1,063 K's in 1,135 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Los Angeles (-150)
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Additional Resources:
Colorado Rockies - Twitter
Los Angeles Angels - Twitter